KC 12291: An Atypical Sodium Channel Blocker with Myocardial Antiischemic Properties

Cardiovascular Drug Reviews

Volumn 22, Issue 1, 2004, Pages 17-26

  John, Gareth W ^a   Létienne, Robert ^a   Le Grand, Bruno ^a   Pignier, Christophe ^a   Vacher, Bernard ^a   Patoiseau, Jean Francois ^a   Colpaert, Francis C ^a   Coulombe, Alain ^b  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^b CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

Author keywords

Calcium overload; Cardioprotection; KC 12291; Myocardial ischemia; Sodium channels; Sodium loading; Sustained Na+ current

Indexed keywords

1 (5 PHENYL 1,2,4 THIADIAZOL 3 YLOXYPROPYL) 3 [N METHYL N [2 (3,4 DIMETHOXYPHENYL)ETHYL]AMINO]PROPANE; KC 12291; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

DRUG ACTIVITY; DRUG DESIGN; DRUG MECHANISM; DRUG METABOLISM; DRUG STRUCTURE; ENERGY; HEART ATRIUM; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SODIUM CURRENT; SODIUM LOAD;

EID: 1642352810     PISSN: 08975957     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3466.2004.tb00129.x     Document Type: Review

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