Cardioprotective actions of KC 12291: I. Inhibition of voltage-gated Na+ channels in ischemia delays myocardial Na+ overload

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 358, Issue 5, 1998, Pages 547-553

  Decking, Ulrich K M ^a   Hartmann, Matthias ^a   Rose, Horst ^b   Brückner, Reinhard ^b   Meil, Jörg ^b   Schrader, Jürgen ^c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Solvay Pharmaceuticals GmbH   (Germany)

^c NONE

Author keywords

23Na NMR spectroscopy; Heart; Inhibition; Ischemia; Na+ channels; Na+ overload

Indexed keywords

1 (5 PHENYL 1,2,4 THIADIAZOL 3 YLOXYPROPYL) 3 [N METHYL N [2 (3,4 DIMETHOXYPHENYL)ETHYL]AMINO]PROPANE HYDROCHLORIDE; POTASSIUM ION; SODIUM CHANNEL; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; FEMALE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATCH CLAMP; RAT; SODIUM CURRENT; VOLTAGE CLAMP;

EID: 0031774211     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005291     Document Type: Article

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