Aerobic Exercise Attenuates Airway Inflammatory Responses in a Mouse Model of Atopic Asthma

Journal of Immunology

Volumn 172, Issue 7, 2004, Pages 4520-4526

  Pastva, Amy ^a   Estell, Kim ^a   Schoeb, Trenton R ^b   Atkinson, T Prescott ^c   Schwiebert, Lisa M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; CELL ADHESION MOLECULE; CYTOKINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXERCISE; EXPERIMENTAL MODEL; FEMALE; FITNESS; GENE EXPRESSION REGULATION; HEALTH STATUS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR TRANSPORT; LEUKOCYTE; LUNG STRUCTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REGULATORY MECHANISM; RESPIRATORY TRACT INFLAMMATION; TISSUE REPAIR; TRAINING;

EID: 1642347219     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.7.4520     Document Type: Article

References (46)

1. O'Byrne, P. M. 1996. Airway inflammation and asthma. Aliment. Pharmacol. Ther. 10:18.
2. Christman, J. W., R. T. Sadikot, and T. R. Blackwell. 2000. The role of nuclear factor-κB in pulmonary diseases. Chest 117:1482.
3. Mannino, D. M., D. M. Homa, C. A. Pertowski, A. Ashizawa, L. L. Nixon, C. A. Johnson, L. B. Ball, E. Jack, and D. S. Kang. 1998. Surveillance for asthma-United States, 1960-1995. MMWR 47:1.
4. Pedersen, B. K., and L. Hoffman-Goetz. 2000. Exercise and the immune system: regulation, integration, and adaptation. Physiol. Rev. 80:1055.
5. Woods, J. A., Q. Lu, M. A. Ceddia, and T. Lowder. 2000. Exercise-induced modulation of macrophage function. Immunol. Cell Biol. 78:545.
6. Ceddia, M. A., E. W. Voss, and J. A. Woods. 2000. Intracellular mechanisms are responsible for the exhaustive exercise-induced suppression of macrophage antigen presentation. J. Appl. Physiol. 88:804.
7. Emtner, M., M. Herala, and G. Stalenheim. 1996. High-intensity physical training in adults with asthma: a 10-week rehabilitation program. Chest 109:323.
8. Emmer, M., M. Finne, and G. Stalenheim. 1998. A three year follow-up of asthmatic patients participating in a ten week rehabilitation program with emphasis on physical training. Arch. Phys. Med. Rehabil. 79:539.
9. Matsumoto, I., H. Araki, K. Tsuda, H. Odajima, S. Nishima, Y. Higaki, H. Tanaka, M. Tanaka, and M. Shindo. 1999. Effects of swimming training on aerobic capacity and exercise induced bronchoconstriction in children with bronchial asthma. Thorax 54:196.
10. Henriksen, J. M., and T. T. Nielsen. 1983. Effect of physical training on exercise-induced bronchoconstriction. Acta Paediatr. Scand. 72:31.
11. Hallstrand, T. S., P. W. Bates, and R. B. Schoene. 2000. Aerobic conditioning in mild asthma decreases the hyperpnea of exercise and improves exercise and ventilatory capacity. Chest 118:1460.
12. American Thoracic Society. 1999. Pulmonary rehabilitation-1999. Am. J. Respir. Crit. Care Med. 159:1666.
13. Satta, A. 2000. Exercise training in asthma. J. Sports Med. Phys. Fitness 40:277.
14. Cooper, C. B. 2001. Exercise in chronic pulmonary disease: limitations and rehabilitation. Med. Sci. Sports Exer. 33:S643.
15. Duguet, A., K. Biyah, E. Minshall, R. Gomes, C. Wang, M. Taoudi-benchekroun, J. H. T. Bates, and D. H. Eidelman. 2000. Bronchial responsiveness among inbred mouse strains. Am. J. Respir. Crit. Care Med. 161:839.
16. Herz, U., U. Lumpp, A. Daser, E. W. Gelfand, and H. Renz. 1996. Murine animal models to study the central role of T cells in immediate-type hypersensitivity responses. Adv. Exp. Med. Biol. 409:25.
17. Fernando, P., A. Bonen, and L. Hoffman-Goetz. 1993. Predicting submaximal oxygen consumption during treadmill running in mice. Can. J. Physiol. Pharmacol. 71:854.
18. Woods, J. A., J. M. Davis, E. P. Mayer, A. Ghaffar, and R. R. Pate. 1993. Exercise increases inflammatory macrophage antitumor cytotoxicity. J. Appl. Physiol. 75: 879.
19. Woods, J. A., J. M. Davis, E. P. Mayer, A. Ghaffar, and R. R. Pate. 1994. Effects of exercise on macrophage activation for antitumor cytotoxicity. J. Appl. Physiol. 76:2177.
20. Schefer, V., and M. I. Talan. 1996. Oxygen consumption in adult and aged C57BL/6J mice during acute treadmill exercise of different intensity. Exp. Gerontol. 31:387.
21. MacNeil, B., and L. Hoffman-Goetz. 1993. Effect of exercise on natural cytotoxicity and pulmonary tumor metastases in mice. Med. Sci. Sports Exer. 25:922.
22. ACCP/AACVPR Pulmonary Guidelines Panel. 1997. Pulmonary rehabilitation: joint ACCP/AACVPR evidence-based guidelines. Chest 112:1363.
23. British Thoracic Society Standards of Care Subcommittee. 2001. Pulmonary rehabilitation: British Thoracic Society Standards of Care Subcommittee on pulmonary rehabilitation. Thorax 59:827.
24. Hickman-Davis, J. M., J. R. Lindsey, S. Zhu, and S. Matalon. 1998. Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages. Am. J. Physiol. 274:L270.
25. Trifilieff, A., A. El-Hashim, and C. Bertrand. 2000. Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment. Am J. Physiol. 279:L1120.
26. Tousson, A., B. A. Van Tine, A. P. Naren, G. M. Shaw, and L. M. Schwiebert. 1998. Characterization of CFTR expression and chloride channel activity in human endothelia. Am. J. Physiol. 275:C1555.
27. Nemzek, J. A., G. L. Bolgos, B. A. Williams, and D. G. Remick. 2001. Difference in normal values for murine white blood cell counts and other hematological parameters based on sampling site. Inflamm. Res. 50:523.
28. Laitinen, L. A., and A. Laitinen. 1996. Remodeling of the asthmatic airways by glucocorticosteroids: J. Allergy Clin. Immunol. 97:153.
29. Lee, N. A., E. W. Gelfand, and J. J. Lee. 2001. Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology? J. Allergy Clin. Immunol. 107:945.
30. Tomkinson, A., G. Cieslewicz, C. Duez, K. Larson, J. J. Lee, and E. W. Gelfand. 2001. Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice. Am J. Respir. Crit. Care Med. 163:721.
31. Wells, T. N. C., and A. E. I. Proudfoot. 1999. Chemokine receptors and their antagonists in allergic disease. Inflamm. Res. 48:353.
32. Wills-Karp, M. 1999. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 17:255.
33. Baldwin, A. S., Jr. 1996. The NFκB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649.
34. Wenzel, S. E., L. B. Schwarz, E. L. Langmack, J. L. Halliday, J. B. Trudeau, R. L. Gibbs, and H. W. Chu. 1999. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am. J. Respir. Crit. Care Med. 160:1001.
35. Ordonez, C. L., T. E. Shaughnessy, M. A. Matthay, and J. V. Fahy. 2000. Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: clinical and biologic significance. Am. J. Respir. Crit. Care Med. 161: 1185.
36. Poynter, M. E., C. G. Irvin, and Y. M. Janssen-Heininger. 2002. Rapid activation of nuclear factor-κB in airway epithelium in a murine model of allergic airway inflammation. Am. J. Pathol. 160:1325.
37. Taube, C., A. Dakhama, Y. Rha, K. Takeda, A. Joetham, J. Park, A. Balhom, T. Takai, K. R. Poch, J. A. Nick, and E. W. Gelfand. 2003. Transient neutrophil infiltration after allergen challenge is dependent on specific antibodies and FcγIII receptors. J. Immunol. 170:4301.
38. Wolyniec, W. W. 1998. Reduction of antigen-induced airway hyperreactivity and eosinophilia in ICAM-1-deficient mice. Am. J. Respir. Crit. Care Med. 18:777.
39. Uyama, O. D. 1995. Role of eosinophils and cell adhesion molecules in the allergen-induced asthmatic response of rats. Res. Commun. Mol. Pathol. Pharmacol. 90:3.
40. Schwiebert, L. M., C. Stellato, and R. P. Schleimer. 1996. The epithelium as a target of glucocorticoid action in the treatment of asthma. Am. J. Respir. Crit. Care Med. 154:S16.
41. Yang, L., L. Cohn, d. Zhang, R. Homer, A. Ray, and R. Prabir. 1998. Essential role of nuclear factor κB in the induction of eosinophilia in allergic airway inflammation. J. Exp. Med. 188:1739.
42. Nagatomi, R., T. Kaifu, M. Okutsu, X. Zhang, O. Kanemi, and H. Ohmori. 2000. Modulation of the immune system by the autonomic nervous system and its implication in immunological changes after training. Exerc. Immunol. Rev. 6:54.
43. Adcock, I. M., and G. Caramor. 2001. Cross-talk between pro-inflammatory transcription factors and glucocorticoids. Immunol. Cell Biol. 79:376.
44. Auphan, N., J. A. DiDonato, C. Rosette, A. Helmberg, and M. Karin. 1995. Immumosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270:286.
45. Tschumperlin, D. J., J. D. Shively, M. A. Swartz, E. S. Silverman, K. J. Haley, G. Raab, and J. M. Drazen. 2002. Mechanotransduction in the lung: bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression. Am. J. Physiol. 282:L904.
46. Kumar, A., S. Lnu, R. Malya, D. Barron, J. Moore, D. B. Corry, and A. M. Boriek. 2003. Mechanical stretch activates nuclear factor-κB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma. FASEB J. 17:1800.