Theoretical and experimental study on theophylline release from stearic acid cylindrical delivery systems

Journal of Controlled Release

Volumn 92, Issue 3, 2003, Pages 275-289

  Grassi, Mario ^a   Voinovich, Dario ^a   Franceschinis, Erica ^a   Perissutti, Beatrice ^a   Filipovic Grcic, Jelena ^b  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Mathematical modelling; Melt extrusion; Ram extruder; Sustained release; Theophylline

Indexed keywords

DIFFUSION; DISSOLUTION; EXTRUSION; HYDROPHILICITY; MATHEMATICAL MODELS; POLYETHYLENE GLYCOLS;

DRUG DIFFUSION;

CONTROLLED DRUG DELIVERY;

LACTOSE; MACROGOL 6000; PHARMATOSE 200; STEARIC ACID; THEOPHYLLINE;

ARTICLE; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; HYDROPHILICITY; KINETICS; MATHEMATICAL MODEL; PRIORITY JOURNAL; THEORETICAL STUDY;

ALGORITHMS; COMPUTER SIMULATION; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG DELIVERY SYSTEMS; ELECTRON PROBE MICROANALYSIS; KINETICS; LACTOSE; MODELS, THEORETICAL; POLYETHYLENE GLYCOLS; PRESSURE; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; STEARIC ACIDS; THEOPHYLLINE;

EID: 1642344771     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00330-4     Document Type: Article

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