N-linked glycosylation of platelet P2Y12 ADP receptor is essential for signal transduction but not for ligand binding or cell surface expression

FEBS Letters

Volumn 562, Issue 1-3, 2004, Pages 111-117

  Zhong, Xiaotian ^a   Kriz, Ron ^a   Seehra, Jasbir ^a   Kumar, Ravindra ^a  

^a PFIZER INC   (United States)

Author keywords

2MeSADP, 2 methyl thiol adenosine diphosphate; 2MeSAMP, 2 methyl thiol adenosine monophosphate; Adenosine diphosphate receptor; Adenylyl cyclase; G protein coupled receptor; N linked glycosylation; Signal transduction; Surface expression

Indexed keywords

ADENOSINE DIPHOSPHATE; GLYCAN DERIVATIVE; PURINE P2Y12 RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SURFACE; CERCOPITHECIDAE; GLYCOSYLATION; LIGAND BINDING; N LINKED GLYCOSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENOSINE DIPHOSPHATE; ADENYLATE CYCLASE; ANIMALS; BLOOD PLATELETS; CELL LINE; CELL MEMBRANE; GLYCOSYLATION; LIGANDS; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; POLYSACCHARIDES; PROTEIN BINDING; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION;

EID: 1642320995     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(04)00191-7     Document Type: Article

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