Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity

Nature Genetics

Volumn 33, Issue 4, 2003, Pages 477-485

  Winrow, Christopher J ^a,c   Hemming, Matthew L ^a   Allen, Duane M ^a   Quistad, Gary B ^b   Casida, John E ^b   Barlow, Carrolee ^a,c  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYL OCTYLPHOSPHONOFLUORIDATE; NEUROTOXIC ESTERASE; ORGANOPHOSPHATE; ORGANOPHOSPHATE INSECTICIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EXPOSURE; GENE EXPRESSION; GENE MAPPING; HYPERACTIVITY; MORTALITY; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL;

ACETYLCHOLINESTERASE; ALLELES; AMINO ACID SEQUENCE; ANIMALS; BETA-GALACTOSIDASE; BLOTTING, NORTHERN; BRAIN; CARBOXYLIC ESTER HYDROLASES; DATABASES; EXPRESSED SEQUENCE TAGS; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; HYPERKINESIS; IN SITU HYBRIDIZATION, FLUORESCENCE; INSECTICIDES; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NEURONS; ORGANOPHOSPHORUS COMPOUNDS; PHENOTYPE; PRECIPITIN TESTS; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; TISSUE DISTRIBUTION;

ANIMALIA; MAMMALIA;

EID: 0037380036     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1131     Document Type: Article

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