메뉴 건너뛰기




Volumn 18, Issue 2, 2004, Pages 107-110

Chemoprotective Effect of Plant Phenolics against Anthracycline-induced Toxicity on Rat Cardiomyocytes. Part I. Silymarin and its Flavonolignans

Author keywords

ATP; Chemoprotective activity; Doxorubicin; Flavonolignans; Rat cardiomyocyte; Silymarin

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANTHRACYCLINE ANTIBIOTIC AGENT; DEHYDROSILIBININ; DOXORUBICIN; FLAVONOLIGNAN; IRON; LACTATE DEHYDROGENASE; PHENOL DERIVATIVE; PLANT EXTRACT; PROTECTIVE AGENT; RAZOXANE; SILIBININ; SILIDIANIN; SILYLCHRISTIN; SILYMARIN; UNCLASSIFIED DRUG;

EID: 1642279578     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1415     Document Type: Article
Times cited : (88)

References (20)
  • 1
    • 0034964186 scopus 로고    scopus 로고
    • Silybin, a new iron-chelating agent
    • Borsari M, Gabbi C, Ghelfi F, et al. 2001. Silybin, a new iron-chelating agent. J Inorg Biochem 85: 123-129.
    • (2001) J Inorg Biochem , vol.85 , pp. 123-129
    • Borsari, M.1    Gabbi, C.2    Ghelfi, F.3
  • 2
    • 0035747280 scopus 로고    scopus 로고
    • Neonatal rat cardiomyocytes - A model for the study of morphological, biochemical and electrophysiological characteristics of the heart
    • Chlopčíková S, Psotová J, Miketová P. 2001. Neonatal rat cardiomyocytes - a model for the study of morphological, biochemical and electrophysiological characteristics of the heart. Biomed Papers 145: 49-55.
    • (2001) Biomed Papers , vol.145 , pp. 49-55
    • Chlopčíková, S.1    Psotová, J.2    Miketová, P.3
  • 3
    • 24544462794 scopus 로고    scopus 로고
    • Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Phenolic acids
    • in press
    • Chlopčíková Š, Psotová J, Miketová P, Šimanek V. 2003. Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Phenolic acids. Phytother Res, in press.
    • (2003) Phytother Res
    • Chlopčíková, Š.1    Psotová, J.2    Miketová, P.3    Šimanek, V.4
  • 4
    • 0029784750 scopus 로고    scopus 로고
    • Cytoprotective agents for anthracyclines
    • Dorr RT. 1996. Cytoprotective agents for anthracyclines. Semin Oncol 23 (Suppl. 8): 23-34.
    • (1996) Semin Oncol , vol.23 , Issue.SUPPL. 8 , pp. 23-34
    • Dorr, R.T.1
  • 5
    • 0037415383 scopus 로고    scopus 로고
    • Primary cultures of human hepatocytes as a tool in cytotoxicity studies: Cell protection against model toxins by flavonolignans obtained from Silybum marianum
    • Dvořák Z, Kosina P, Walterová D, Šimánek V, Bachleda P, Ulrichová J. 2003. Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum. Toxicol Lett 137: 201-212.
    • (2003) Toxicol Lett , vol.137 , pp. 201-212
    • Dvořák, Z.1    Kosina, P.2    Walterová, D.3    Šimánek, V.4    Bachleda, P.5    Ulrichová, J.6
  • 6
    • 0032008339 scopus 로고    scopus 로고
    • Milk thistle (Silybum marianum) for the therapy of liver disease
    • Flora K, Hahn M, Rosen H, Benner K. 1998. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol 93: 139-143.
    • (1998) Am J Gastroenterol , vol.93 , pp. 139-143
    • Flora, K.1    Hahn, M.2    Rosen, H.3    Benner, K.4
  • 8
    • 0025283897 scopus 로고
    • Doxorubicin (adriamycin): A critical review of free radical-dependent mechanisms of cytotoxicity
    • Keizer HG, Pinedo HM, Schuurhuis GJ, Joenje H. 1990. Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity. Pharmac Ther 47: 219-231.
    • (1990) Pharmac Ther , vol.47 , pp. 219-231
    • Keizer, H.G.1    Pinedo, H.M.2    Schuurhuis, G.J.3    Joenje, H.4
  • 10
    • 1642309758 scopus 로고    scopus 로고
    • Patent Number: 5,714, 473. Use of Flavolignans as Adjuvants in Tumour Therapy. February 3, 1998
    • Lentzen H, Mengs U, Odenthal K-P. Patent Number: 5,714, 473. Use of Flavolignans as Adjuvants in Tumour Therapy. February 3, 1998.
    • Lentzen, H.1    Mengs, U.2    Odenthal, K.-P.3
  • 11
    • 0032965572 scopus 로고    scopus 로고
    • Role of iron in anthracycline cardiotoxicity: New tunes for an old song?
    • Minotti G, Cairo G, Monti E. 1999. Role of iron in anthracycline cardiotoxicity: new tunes for an old song? FASEB J 13: 199-212.
    • (1999) FASEB J , vol.13 , pp. 199-212
    • Minotti, G.1    Cairo, G.2    Monti, E.3
  • 12
    • 0035041124 scopus 로고    scopus 로고
    • Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines
    • Perego P, Corna E, De Cesare M, et al. 2001. Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines. Curr Med Chem 8: 31-37.
    • (2001) Curr Med Chem , vol.8 , pp. 31-37
    • Perego, P.1    Corna, E.2    De Cesare, M.3
  • 13
    • 0036219122 scopus 로고    scopus 로고
    • Influence of silymarin and its flavonolignans on doxorubicin-iron induced lipid peroxidation in rat heart microsomes and mitochondria in comparison with quercetin
    • Psotová J, Chlopčíková Š, Grambal F, Šimánek V, Ulrichová J. 2002a. Influence of silymarin and its flavonolignans on doxorubicin-iron induced lipid peroxidation in rat heart microsomes and mitochondria in comparison with quercetin. Phytother Res 16: S 63-67.
    • (2002) Phytother Res , vol.16
    • Psotová, J.1    Chlopčíková, Š.2    Grambal, F.3    Šimánek, V.4    Ulrichová, J.5
  • 14
    • 1642371603 scopus 로고    scopus 로고
    • Can dexrazoxane be replayed by silibinin in the anthracycline antibiotics therapy? Comparative study in rat cardiomyoyctes
    • Pasquier C (ed.). Monduzzi Editore S.p.A. Medimond Inc: Bologna
    • Psotová J, Chlopčíková Š, Miketová P. 2002b. Can dexrazoxane be replayed by silibinin in the anthracycline antibiotics therapy? Comparative study in rat cardiomyoyctes. In XI. Biennial Meeting of the Society for Free Radical Research International Pasquier C (ed.). Monduzzi Editore S.p.A. Medimond Inc: Bologna; 711-715.
    • (2002) XI. Biennial Meeting of the Society for Free Radical Research International , pp. 711-715
    • Psotová, J.1    Chlopčíková, Š.2    Miketová, P.3
  • 15
    • 0035211762 scopus 로고    scopus 로고
    • The use of silymarin in the treatment of liver diseases
    • Saller R, Meier R, Brignoli R. 2001. The use of silymarin in the treatment of liver diseases. Drugs 61: 2035-2063.
    • (2001) Drugs , vol.61 , pp. 2035-2063
    • Saller, R.1    Meier, R.2    Brignoli, R.3
  • 16
    • 0013413959 scopus 로고    scopus 로고
    • Extract from Silybum marianum as a nutraceutical: A double-blind placebo-controlled study in healthy young men
    • Šimánek V, Škottová N, Bartek J, et al. 2001. Extract from Silybum marianum as a nutraceutical: a double-blind placebo-controlled study in healthy young men. Czech J Food Sci 19: 106-110.
    • (2001) Czech J Food Sci , vol.19 , pp. 106-110
    • Šimánek, V.1    Škottová, N.2    Bartek, J.3
  • 17
    • 0035093439 scopus 로고    scopus 로고
    • Silymarin - An extract from the milk thistle (Silybum marianum) - Is it a drug or nutritional supplement?
    • Šimánek V, Walterová D, Vičar J, et al. 2001. Silymarin - an extract from the milk thistle (Silybum marianum) - is it a drug or nutritional supplement? Česká Slov Farm 50: 66-69.
    • (2001) Česká Slov Farm , vol.50 , pp. 66-69
    • Šimánek, V.1    Walterová, D.2    Vičar, J.3
  • 18
    • 0344994584 scopus 로고    scopus 로고
    • Activities of silymarin and its flavonolignans upon low density lipoprotein oxidizability in vitro
    • Škottová N, Krečman V, Šimánek V. 1999. Activities of silymarin and its flavonolignans upon low density lipoprotein oxidizability in vitro. Phytother Res 13: 535-557.
    • (1999) Phytother Res , vol.13 , pp. 535-557
    • Škottová, N.1    Krečman, V.2    Šimánek, V.3
  • 20
    • 0034859659 scopus 로고    scopus 로고
    • Silymarin: A review of its clinical properties in the management of hepatic disorders
    • Wellington K, Jarvis B. 2001. Silymarin: A review of its clinical properties in the management of hepatic disorders. BioDrugs 15: 465-489.
    • (2001) BioDrugs , vol.15 , pp. 465-489
    • Wellington, K.1    Jarvis, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.