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Volumn 447, Issue 6, 2004, Pages 867-874

Dichloroacetate does not speed phase-II pulmonary V̇O2 kinetics following the onset of heavy intensity cycle exercise

Author keywords

Gas exchange; Oxygen uptake; Respiration

Indexed keywords

ADENOSINE TRIPHOSPHATE; DICHLOROACETIC ACID; LACTIC ACID; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 1642276362     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-003-1209-6     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 0032547309 scopus 로고    scopus 로고
    • Inactivation of aconitase and oxoglutarate dehydrogenase in skeletal muscle in vitro by superoxide anions and/or nitric oxide
    • Andersson U, Leighton B, Young ME, Blomstrand E, Newsholme EA (1998) Inactivation of aconitase and oxoglutarate dehydrogenase in skeletal muscle in vitro by superoxide anions and/or nitric oxide. Biochem Biophys Res Commun 249:512-516
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 512-516
    • Andersson, U.1    Leighton, B.2    Young, M.E.3    Blomstrand, E.4    Newsholme, E.A.5
  • 4
    • 0029800383 scopus 로고    scopus 로고
    • Influence of muscle fiber type and pedal frequency on oxygen uptake kinetics of heavy exercise
    • Barstow TJ, Jones AM, Nguyen PH, Casaburi R (1996) Influence of muscle fiber type and pedal frequency on oxygen uptake kinetics of heavy exercise. J Appl Physiol 81:1642-1650
    • (1996) J Appl Physiol , vol.81 , pp. 1642-1650
    • Barstow, T.J.1    Jones, A.M.2    Nguyen, P.H.3    Casaburi, R.4
  • 5
    • 0037088859 scopus 로고    scopus 로고
    • Effects of prior contractions on muscle microvascular oxygen pressure at onset of subsequent contractions
    • Lond
    • Behnke BJ, Kindig CA, Musch TI, Sexton WL, Poole DC (2002) Effects of prior contractions on muscle microvascular oxygen pressure at onset of subsequent contractions. J Physiol (Lond) 539:927-934
    • (2002) J Physiol , vol.539 , pp. 927-934
    • Behnke, B.J.1    Kindig, C.A.2    Musch, T.I.3    Sexton, W.L.4    Poole, D.C.5
  • 6
    • 1842296939 scopus 로고    scopus 로고
    • Maximum rate of oxygen uptake by human skeletal muscle in relation to maximal activities of enzymes in the Krebs cycle
    • Lond
    • Blomstrand E, Radegran G, Saltin B (1997) Maximum rate of oxygen uptake by human skeletal muscle in relation to maximal activities of enzymes in the Krebs cycle. J Physiol (Lond) 501:455-460
    • (1997) J Physiol , vol.501 , pp. 455-460
    • Blomstrand, E.1    Radegran, G.2    Saltin, B.3
  • 7
    • 0032947296 scopus 로고    scopus 로고
    • Nitric oxide and mitochondrial respiration
    • Brown GC (1999) Nitric oxide and mitochondrial respiration. Biochim Biophys Acta 1411:351-369
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 351-369
    • Brown, G.C.1
  • 8
    • 0034981132 scopus 로고    scopus 로고
    • Effect of prior exercise and recovery duration on oxygen uptake kinetics during heavy exercise in humans
    • Burnley M, Doust JH, Carter H, Jones AM (2001) Effect of prior exercise and recovery duration on oxygen uptake kinetics during heavy exercise in humans. Exp Physiol 86:417-425
    • (2001) Exp Physiol , vol.86 , pp. 417-425
    • Burnley, M.1    Doust, J.H.2    Carter, H.3    Jones, A.M.4
  • 9
    • 0029998238 scopus 로고    scopus 로고
    • Different inhibitory actions of NO and peroxynitrite on mitochondrial electron transport
    • Cassina A, Radi R (1996) Different inhibitory actions of NO and peroxynitrite on mitochondrial electron transport. Arch Biophys Biochem 328:309-316
    • (1996) Arch Biophys Biochem , vol.328 , pp. 309-316
    • Cassina, A.1    Radi, R.2
  • 10
    • 0035665489 scopus 로고    scopus 로고
    • Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise
    • Evans MK, Savasi I, Heigenhauser GJF, Spriet LL (2001) Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. Am J Physiol 281:E1144-E1150
    • (2001) Am J Physiol , vol.281
    • Evans, M.K.1    Savasi, I.2    Heigenhauser, G.J.F.3    Spriet, L.L.4
  • 11
    • 0029688119 scopus 로고    scopus 로고
    • The slow component of oxygen uptake kinetics in humans
    • Gaesser GA, Poole DC (1996) The slow component of oxygen uptake kinetics in humans. Exerc Sport Sci Rev 24:35-70
    • (1996) Exerc Sport Sci Rev , vol.24 , pp. 35-70
    • Gaesser, G.A.1    Poole, D.C.2
  • 12
    • 0032806174 scopus 로고    scopus 로고
    • PDC activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humans
    • Gibala MJ, Saltin B (1999) PDC activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humans. Am J Physiol 277:E33-E38
    • (1999) Am J Physiol , vol.277
    • Gibala, M.J.1    Saltin, B.2
  • 17
    • 0002491051 scopus 로고
    • Muscular exercise, lactic acid and the supply and utilisation of oxygen
    • Hill AV, Long CNH, Lupton H (1924) Muscular exercise, lactic acid and the supply and utilisation of oxygen. Proc R Soc Lond B Biol Sci 96:438-475
    • (1924) Proc R Soc Lond B Biol Sci , vol.96 , pp. 438-475
    • Hill, A.V.1    Long, C.N.H.2    Lupton, H.3
  • 18
    • 0035061797 scopus 로고    scopus 로고
    • 2 at the onset of contractions in Xenopus single skeletal muscle fibers
    • 2 at the onset of contractions in Xenopus single skeletal muscle fibers. J Appl Physiol 90:1871-1876
    • (2001) J Appl Physiol , vol.90 , pp. 1871-1876
    • Hogan, M.C.1
  • 19
    • 0037305489 scopus 로고    scopus 로고
    • 2 at onset of contractions in Xenopus single muscle fibers
    • 2 at onset of contractions in Xenopus single muscle fibers. Am J Physiol 284:R481-R485
    • (2003) Am J Physiol , vol.284
    • Howlett, R.A.1    Hogan, M.C.2
  • 22
    • 0032706542 scopus 로고    scopus 로고
    • Skeletal muscle metabolism during high-intensity sprint exercise is unaffected by dichloroacetate or acetate infusion
    • Howlett RA, Heigenhauser GJF, Spriet LL (1999) Skeletal muscle metabolism during high-intensity sprint exercise is unaffected by dichloroacetate or acetate infusion. J Appl Physiol 87:1747-1751
    • (1999) J Appl Physiol , vol.87 , pp. 1747-1751
    • Howlett, R.A.1    Heigenhauser, G.J.F.2    Spriet, L.L.3
  • 24
    • 0032966627 scopus 로고    scopus 로고
    • Nitric oxide inhibits cardiac energy production via inhibition of mitochondrial creatine kinase
    • Kaasik A, Minajeva A, DeSousa E, Ventura-Clapier R, Veksler V (1999) Nitric oxide inhibits cardiac energy production via inhibition of mitochondrial creatine kinase. FEBS Lett 444:75-77
    • (1999) FEBS Lett , vol.444 , pp. 75-77
    • Kaasik, A.1    Minajeva, A.2    DeSousa, E.3    Ventura-Clapier, R.4    Veksler, V.5
  • 25
    • 0034919250 scopus 로고    scopus 로고
    • Effect of L-NAME on oxygen uptake kinetics during heavy-intensity exercise in the horse
    • Kindig CA, McDonough P, Erickson HH, Poole DC (2001) Effect of L-NAME on oxygen uptake kinetics during heavy-intensity exercise in the horse. J Appl Physiol 91:891-896
    • (2001) J Appl Physiol , vol.91 , pp. 891-896
    • Kindig, C.A.1    McDonough, P.2    Erickson, H.H.3    Poole, D.C.4
  • 26
    • 0036024153 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition speeds oxygen uptake kinetics in horses during moderate domain running
    • Kindig CA, McDonough P, Erickson HH, Poole DC (2002) Nitric oxide synthase inhibition speeds oxygen uptake kinetics in horses during moderate domain running. Respir Physiol Neurobiol 132:169-178
    • (2002) Respir Physiol Neurobiol , vol.132 , pp. 169-178
    • Kindig, C.A.1    McDonough, P.2    Erickson, H.H.3    Poole, D.C.4
  • 28
    • 0023260998 scopus 로고
    • Effect of interbreath fluctuations on characterising exercise gas exchange kinetics
    • Lamarra N, Whipp BJ, Ward SA, Wasserman K (1987) Effect of interbreath fluctuations on characterising exercise gas exchange kinetics. J Appl Physiol 62:2003-2012
    • (1987) J Appl Physiol , vol.62 , pp. 2003-2012
    • Lamarra, N.1    Whipp, B.J.2    Ward, S.A.3    Wasserman, K.4
  • 29
    • 0030612170 scopus 로고    scopus 로고
    • 2 kinetics in heavy submaximal exercise by hyperoxia and prior high-intensity exercise
    • 2 kinetics in heavy submaximal exercise by hyperoxia and prior high-intensity exercise. J Appl Physiol 83:1318-1325
    • (1997) J Appl Physiol , vol.83 , pp. 1318-1325
    • MacDonald, M.J.1    Pedersen, P.K.2    Hughson, R.L.3
  • 30
    • 0021814235 scopus 로고
    • 2 and phosphorylcreatine level. Implications for the control of respiration
    • 2 and phosphorylcreatine level. Implications for the control of respiration. J Gen Physiol 86:135-165
    • (1985) J Gen Physiol , vol.86 , pp. 135-165
    • Mahler, M.1
  • 32
    • 0025952096 scopus 로고
    • Asymmetries of oxygen uptake transients at the on- and offset of heavy exercise in humans
    • Lond
    • Paterson DH, Whipp BJ (1991) Asymmetries of oxygen uptake transients at the on- and offset of heavy exercise in humans. J Physiol (Lond) 443:575-586
    • (1991) J Physiol , vol.443 , pp. 575-586
    • Paterson, D.H.1    Whipp, B.J.2
  • 34
    • 0037379327 scopus 로고    scopus 로고
    • Effect of pedal rate on primary and slow component oxygen uptake kinetics during heavy exercise
    • Pringle JSM, Doust JH, Carter H, Tolfrey K, Jones AM (2003) Effect of pedal rate on primary and slow component oxygen uptake kinetics during heavy exercise. J Appl Physiol 94:1501-1507
    • (2003) J Appl Physiol , vol.94 , pp. 1501-1507
    • Pringle, J.S.M.1    Doust, J.H.2    Carter, H.3    Tolfrey, K.4    Jones, A.M.5
  • 35
    • 0034806619 scopus 로고    scopus 로고
    • Local perfusion and metabolic demand during exercise: A noninvasive MRI method of assessment
    • Richardson RS, Haseler LJ, Nygren AT, Bluml S, Frank LR (2001) Local perfusion and metabolic demand during exercise: a noninvasive MRI method of assessment. J Appl Physiol 91:1845-53
    • (2001) J Appl Physiol , vol.91 , pp. 1845-1853
    • Richardson, R.S.1    Haseler, L.J.2    Nygren, A.T.3    Bluml, S.4    Frank, L.R.5
  • 36
    • 0037107411 scopus 로고    scopus 로고
    • The acetyl group deficit at the onset of contraction in ischaemic canine skeletal muscle
    • Lond
    • Roberts PA, Loxham SJG, Poucher SM, Constantin-Teodosiu, Greenhaff PL (2002) The acetyl group deficit at the onset of contraction in ischaemic canine skeletal muscle. J Physiol (Lond) 544:591-602
    • (2002) J Physiol , vol.544 , pp. 591-602
    • Roberts, P.A.1    Loxham, S.J.G.2    Poucher, S.M.3    Constantin-Teodosiu4    Greenhaff, P.L.5
  • 37
    • 0033179550 scopus 로고    scopus 로고
    • Inferences from pulmonary O2 uptake with respect to intramuscular [phosphocreatine] kinetics during moderate exercise in humans
    • Lond
    • Rossiter HB, Ward SA, Doyle VL, Howe FA, Griffiths JR, Whipp BJ (1999) Inferences from pulmonary O2 uptake with respect to intramuscular [phosphocreatine] kinetics during moderate exercise in humans. J Physiol (Lond) 518:921-932
    • (1999) J Physiol , vol.518 , pp. 921-932
    • Rossiter, H.B.1    Ward, S.A.2    Doyle, V.L.3    Howe, F.A.4    Griffiths, J.R.5    Whipp, B.J.6
  • 40
    • 0036288084 scopus 로고    scopus 로고
    • Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise
    • Savasi I, Evans MK, Heigenhauser GJF, Spriet LL (2002) Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise. Am J Physiol 283:E108-E115
    • (2002) Am J Physiol , vol.283
    • Savasi, I.1    Evans, M.K.2    Heigenhauser, G.J.F.3    Spriet, L.L.4
  • 43
    • 0031951706 scopus 로고    scopus 로고
    • Muscle acetyl group availability is a major determinant of oxygen deficit in humans during submaximal exercise
    • Timmons JA, Gustafsson T, Sundberg CJ, Jansson E, Greenhaff PL (1998) Muscle acetyl group availability is a major determinant of oxygen deficit in humans during submaximal exercise. Am J Physiol 274:E377-E380
    • (1998) Am J Physiol , vol.274
    • Timmons, J.A.1    Gustafsson, T.2    Sundberg, C.J.3    Jansson, E.4    Greenhaff, P.L.5
  • 45
    • 0028172863 scopus 로고
    • 2 uptake kinetics during heavy exercise
    • 2 uptake kinetics during heavy exercise. Med Sci Sports Exerc 26:1319-1326
    • (1994) Med Sci Sports Exerc , vol.26 , pp. 1319-1326
    • Whipp, B.J.1


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