A new hypothesis for microvascular inflammation in shock and multiorgan failure: Self-digestion by pancreatic enzymes

Microcirculation

Volumn 12, Issue 1, 2005, Pages 71-82

  Schmid Schönbein, Geert W ^a   Hugli, Tony E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

Apoptosis; Chymotrypsin; Enteral enzyme blockade; Enzyme blockade; Inflammatory mediators; Intestine; Intestine lavage; Ischemia; Lipase; Pancreas; Trigger mechanisms; Trypsin

Indexed keywords

AMYLASE; ARACHIDONIC ACID; CYTOKINE; ENDOTOXIN; ENZYME PRECURSOR; INTERLEUKIN 6; LEUKOTRIENE; LIPID; MATRIX PROTEIN; NAFAMSTAT MESILATE; NITRIC OXIDE; NUCLEASE; OXYGEN; OXYGEN RADICAL; PANCREAS ENZYME; PHOSPHOLIPID; PROSTAGLANDIN; PROTEINASE; SERINE PROTEINASE INHIBITOR; THROMBOCYTE ACTIVATING FACTOR; TRIACYLGLYCEROL LIPASE;

ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HEMORRHAGIC SHOCK; IN VITRO STUDY; INFLAMMATION; INTESTINE; ISCHEMIA; LEYDIG CELL; MICROCIRCULATION; MICROVASCULATURE; MULTIPLE ORGAN FAILURE; NONHUMAN; OXYGEN TISSUE LEVEL; PERMEABILITY BARRIER; PRIORITY JOURNAL; REVIEW; SEPTIC SHOCK;

ANIMALS; HUMANS; INFLAMMATION; MICROCIRCULATION; MULTIPLE ORGAN FAILURE; PANCREAS; PEPTIDE HYDROLASES; SHOCK;

EID: 16244423025     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1080/10739680590896009     Document Type: Review

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