Microvascular effects of oral interleukin-6 on ischemia/reperfusion in the murine small intestine

American Journal of Pathology

Volumn 156, Issue 4, 2000, Pages 1177-1182

  Rollwagen, Florence M ^a   Li, Ying Yue ^a   Pacheco, Nancy D ^b   Dick, Edward J ^c   Kang, Yuan Hsu ^b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^c AIR FORCE RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HORSERADISH PEROXIDASE; INTERLEUKIN 6;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; GASTROINTESTINAL HEMORRHAGE; INTESTINE EPITHELIUM; INTESTINE ISCHEMIA; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPSIS; SMALL INTESTINE;

EID: 0033842898     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64987-5     Document Type: Article

References (33)

1. Bacterial translocation of the gut flora
2. Regional flow during experimental hemorrhage and crystalloid resuscitation: Persistence of low flow to the splanchnic organs
3. Mechanisms of endotoxin-induced intestinal injury in an hyperdynamic model of sepsis
4. Multiple organ failure
5. IL-6 rescues enterocytes from hemorrhage induced apoptosis in vivo and in vitro by a bcl-2 mediated mechanism
6. Cytokine induced intestinal epithelial hyperpermeability: Role of nitric oxide
7. Modulation of mucosal immunity against Campylobacter jejuni by orally administered cytokines
8. Systemic bacteraemia following haemorrhagic shock in mice: Alleviation with oral interleukin-6
9. Systemic sepsis following hemorrhagic shock: Alleviation with oral interleukin-6
10. Inhibitory effect of interleukin-6 on vascular smooth muscle contraction
11. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney, ultrastructural cytochemistry by a new technique
12. Increased permeability of cerebral vessels to horseradish peroxidase induced by ischemia in Mongolian gerbils
13. Endotoxin-induced endothelial injury and subendothelial accumulation of fibronectin in rat aorta
14. Mucosal permeability after subclinical intestinal ischemia-reperfusion injury: An exploration of possible mechanisms
15. Acid-induced molten globule state of a fully active mutant of human interleukin-6
16. Granulocyte-colony stimulating factor maintains a thermally stable, compact, partially folded structure at pH 2
17. Evidence for an acute phase response in human intestinal epithelial cells
18. On the transfer of serum proteins to the rat intestinal juice
19. Loss of macromolecular barrier function associated with surgical trauma to the intestine
20. Increased gut permeability after hemorrhage is associated with upregulation of local and systemic IL-6
21. Autocrine regulation of epithelial permeability by hypoxia: Role for polarized release of tumor necrosis factor alpha
22. Polarized secretion of IL-6 by IEC-6 intestinal epithelial cells: Differential effects of IL-1 beta and TNF-alpha
23. Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin
24. Synergistic effects of interferon gamma and tumor necrosis factor alpha on T84 cell function
25. Distinct classes of chaperoned IL-6 in human blood: Differential immunological and biological availability
26. High levels of 'complexed' interleukin-6 in human blood
27. Stimulation of the B9 hybridoma cell line by soluble interleukin-6 receptors
28. Epitope peptides from interleukin-6 eceptor which inhibit the growth of human myeloma cells
29. Outcome after hemorrhagic shock in trauma patients
30. Induction mechanism of small intestinal lesions caused by intravenous injection of endotoxin in rats
31. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
32. The endothelin receptor antagonist bosentan restores gut oxygen delivery and reverses intestinal mucosal acidosis in porcine endotoxin shock
33. Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium