Synthesis and antibacterial activity of C2-fluoro, C6-carbamate ketolides, and their C9-oximes

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 4, 2005, Pages 883-887

  Xu, Xiaodong ^a   Henninger, Todd ^a   Abbanat, Darren ^a   Bush, Karen ^a   Foleno, Barbara ^a   Hilliard, Jamese ^a   Macielag, Mark ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Carbamate; Fluoro ketolide; Ketolide; Oxime; Resistant bacteria

Indexed keywords

CARBAMIC ACID DERIVATIVE; KETOLIDE; OXIME DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; FLUORINATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

HAEMOPHILUS INFLUENZAE;

EID: 16244406229     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.067     Document Type: Article

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28. 50) was calculated using the Logistic routine of the SAS suite of programs