Application of iscom antigen preparations in ELISAs for diagnosis of Neospora and Toxoplasma infections

International Journal for Parasitology

Volumn 28, Issue 1, 1998, Pages 187-193

  Björkman, Camilla ^a   Lundén, Anna ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Antigen; ELISA; Iscom; Neospora caninum; Review; Serology; Toxoplasma gondii

Indexed keywords

PARASITE ANTIGEN;

ANTIGEN DETECTION; ANTIGEN SPECIFICITY; CONFERENCE PAPER; DIAGNOSTIC ACCURACY; ENZYME LINKED IMMUNOSORBENT ASSAY; NEOSPORA CANINUM; NONHUMAN; PARASITE IDENTIFICATION; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; ANTIGENS, PROTOZOAN; COCCIDIOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; ISCOMS; NEOSPORA; PROTOZOAN VACCINES; SEROLOGIC TESTS; TOXOPLASMA; TOXOPLASMOSIS;

EID: 0031893999     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(97)00174-4     Document Type: Conference Paper

References (36)

1. [1] Morein B, Sundquist B, Höglund S, Dalsgaard K, Osterhaus A. Iscom, a novel structure for antigenic presentation of membrane proteins from enveloped viruses. Nature 1984; 308: 457-460.
2. [2] Morein B, Lövgren K, Höglund S, Sundquist B. The ISCOM: an immunostimulating complex. Immunol Today 1987; 8: 333-338.
3. [3] Lövgren-Bengtsson K. Preparation and use of adjuvants. In: Kaufmann HE, editor. Immunological methods, methods in Microbiology. London: Academic Press, in press.
4. [4] Claassen I, Osterhaus A. The iscom structure as an immune-enhancing moiety: experience with viral systems. Res Immunol 1992; 143: 531-541.
5. [5] Morein B, Lövgren K, Rönnberg B, Sjölander A, Villacré-Eriksson M. Immunostimulating complexes, clinical potential in vaccine development. Clin Immunotherapeut 1995; 3: 461-475.
6. [6] Barr IG, Mitchell GF. ISCOMs (immunostimulating complexes): the first decade. Immunol Cell Biol 1996; 74: 8-25.
7. [7] Lundén A, Lövgren-Bengtsson K, Sjölander A, Uggla A. Iscoms in parasitological research. Parasitol Today 1996; 12: 320-323.
8. [8] Dubey JP, Beattie CP. Toxoplasmosis of animals and man. Boca Raton, FL: CRC Press, 1988.
9. [9] Bjerkås I, Mohn SF, Presthus J. Unidentified cyst-forming Sporozoon causing encephalomyelitis and myositis in dogs. Zeitschrift für Parasitenkunde 1984; 70: 271-274.
10. [10] Dubey JP, Carpenter JL, Speer CA, Topper MJ, Uggla A. Newly recognized fatal protozoan disease of dogs. J Am Vet Med Assoc 1988; 192: 1269-1285.
11. [11] Dubey JP, Lindsay DS. A review of Neospora caninum and neosporosis. Vet Parasitol 1996; 67: 1-59.
12. [12] Björkman C, Lundén A, Holmdahl J, Barber J, Trees AJ, Uggla A. Neospora caninum in dogs: detection of antibodies by ELISA using an iscom antigen. Parasite Immunol 1994; 16: 643-648.
13. [13] Dubey JP, Lindsay DS, Neosporosis. Parasitol Today 1993; 9: 452-458.
14. [14] Lövgren K, Uggla A, Morein B. A new approach to the preparation of a Toxoplasma gondii membrane antigen for use in ELISA. J Vet Med B 1987; 34: 274-282.
15. [15] Uggla A, Buxton D. Immune responses against Toxoplasma and Sarcocystis infections in ruminants: diagnosis and prospects for vaccination. Revue Scientifique et Technique de l'Office International des Epizooties 1990; 9: 441-462.
16. [16] Uggla A, Hilali M, Lövgren K. Serological responses in Sarcocystis cruzi infected calves challenged with Toxoplasma gondii. Res Vet Sci 1987; 43: 127-129.
17. [17] Hughes HPA. The antigenic structure of Toxoplasma gondii. Lyon Méd 1982; 248: 135-139.
18. [18] Huldt G. Workshop No 3. Serodiagnosis of parasitic infections. Parasitology 1981; 82: 49-55.
19. [19] Santoro F, Afchain D, Pierce R, Cesbron JY, Ovlaque G, Capron A. Serodiagnosis of toxoplasma infection using a purified parasite protein (P30). Clin Exp Immunol 1985; 62: 262-269.
20. [20] Dubey JP, Jenkins MC, Adams DS et al. Antibody responses of cows during an outbreak of neosporis evaluated by indirect fluorescent antibody test and different enzyme linked immunosorbent assays. J Parasitol 1997; 83: 1063-1069.
21. [21] Tenter AM, Vietmeyer C, Johnson AM, Janitschke K, Rommel M, Lehmacher W. ELISAs based on recombinant antigens for sero-epidemiological studies on Toxoplasma gondii infections in cats. Parasitology 1994; 109: 29-36.
22. [22] Jenkins MC, Wouda W, Dubey JP. Serological response over time to recombinant Neospora caninum antigens in cattle after a neosporosis-induced abortion. Clin Diagn Lab Immunol 1997; 4: 270-274.
23. [23] Williams DJL, McGarry J, Guy F, Barber J, Trees AJ. Novel ELISA for detection of Neospora-specific antibodies in cattle. Vet Rec 1997; 140: 328-331.
24. [24] Özel M, Höglund S, Gelderblom HR, Morein B. Quaternary structure of the immunostimulating complex (iscom). J Ultrastruct Mol Struct Res 1989; 102: 240-248.
25. [25] Höglund S, Dalsgaard K, Lövgren K, Sundquist B, Osterhaus A, Morein B. ISCOMs and immunostimulation with viral antigens. In: Harris JR, editor. Subcellular biochemistry, vol. 15. New York: Plenum Publishing, 1989;39-68.
26. [26] Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt Biochem 1976; 72: 248-254.
27. [27] Lundén A, Lövgren K, Uggla A, Araujo FG. Immune responses and resistance to Toxoplasma gondii in mice immunized with antigens of the parasite incorporated into immunostimulating complexes. Infect Immun 1993; 61: 2639-2643.
28. [28] Björkman C, Holmdahl OJM, Uggla A. An indirect enzyme-linked immunoassay (ELISA) for demonstration of antibodies to Neospora caninum in serum and milk of cattle. Vet Parasitol 1997; 68: 251-260.
29. [29] Hemphill A. Subcellular localization and functional characterization of Nc-p43, a major Neospora caninum tachyzoite surface protein. Infect Immun 1996; 64: 4279-4287.
30. [30] Lundén A. Immune responses in sheep after immunization with Toxoplasma gondii antigens incorporated into iscoms. Vet Parasitol 1995; 56: 23-35.
31. [31] Björkman C, Lundén A, Uggla A. Prevalence of antibodies to Neospora caninum and Toxoplasma gondii in Swedish dogs. Acta Vet Scand 1994; 35: 445-447.
32. [32] Koudela B, Svoboda M, Björkman C, Uggla A. Neosporosis in dogs - the first case report in the Czech republic. Vet Med-Czech 1998; 43: 33-36.
33. [33] Conrad PA, Sverlow K, Anderson M, et al. Detection of serum antibody responses in cattle with natural or experimental Neospora infections. J Vet Diagn Invest 1993; 5: 572-578.
34. [34] Holmdahl OJM, Björkman C, Uggta A. A case of Neospora associated bovine abortion in Sweden. Acta Vet Scand 1995; 36: 279-281.
35. [35] Björkman C, Johansson O, Stenlund S, Holmdahl J, Uggla A. Neospora species infection in a herd of dairy cattle. J Am Vet Med Assoc 1996; 208: 1441-1444.
36. [36] Stenlund S, Björkman C, Holmdahl OJM, Kindahl H. Uggla A. Characterisation of a Swedish bovine isolate of Neospora caninum. Parasitol Research 1997; 83: 214-219.