Neospora caninum: Role for immune cytokines in host immunity

Experimental Parasitology

Volumn 85, Issue 1, 1997, Pages 24-34

  Khan, Imtiaz A ^a   Schwartzman, Joseph D ^a   Fonseka, Sujeewa ^a   Kasper, Lloyd H ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; NITRIC OXIDE;

ANIMAL EXPERIMENT; APICOMPLEXA; ARTICLE; CONTROLLED STUDY; FEMALE; HISTOLOGY; HOST PARASITE INTERACTION; IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NEOSPORA CANINUM; NONHUMAN; PRIORITY JOURNAL;

EID: 0031001103     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1996.4110     Document Type: Article

References (25)

1. Anderson M. L., Blanchard P. C., Barr B. C., Dubey J. P., Hoffman R. L., Conrad P. A. Neospora-like protozoan infection as a major cause of abortion in California dairy cattle. Journal of the American Veterinary Association. 198:1991;241-244.
2. Bjorkman C. A., Lunden J., Holmdahl J., Barber A. J., Trees E. Y., Uggla A. Neospora caninum. Parasite Immunology. 16:1994;643-648.
3. Brindley P. J., Gazzinelli R. T., Denkers S. W., Davis J. P., Dubey R., Belfort M. C. Jr., Martins C., Silveira L., Jamra A. P., Waters. Differentiation ofToxoplasma gondii. American Journal of Tropical Medicine and Hygiene. 48:1993;447-456.
4. Candolfi E., Hunter C. A., Remington J. S. Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis. Infection and Immunity. 63:1995;751-756.
5. Dubey J. P., Lindsay D. S., Anderson M. L., Davis S. W., Shen S. K. Induced transplacental transmission ofNeospora caninum. Journal of the American Veterinary Medical Association. 201:1992;709-713.
6. Dubey J. P., Lindsay D. S., Lipscomb T. P. Neosporosis in cats. Veterinary Pathology. 27:1990;335-339.
7. Gazzinelli R. T., Hayashi S., Wysocka M., Carrera L., Kuhn R., Muller W., Roberge F., Trinchieri G., Sher A. Role of IL-12 in the initiation of cell mediated immunity byToxoplasma gondii. Journal of Eukaryotic Microbiology. 41:1994a;9S-9S.
8. Gazzinelli R. T., Hieny S., Wynn T. A., Wolf S., Sher A. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proceedings of the National Academy of Science USA. 90:1993;6115-6119.
9. Gazzinelli R. T., Wysocka M., Hayashi S., Denkers E. Y., Hieny S., Caspar P., Trinchieri G., Sher A. Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection withToxoplasma gondii. Journal of Immunology. 153:1994b;2533-2543.
10. Gregory S. H., Wing E. J., Hoffman R. A., Sher R. L. Reactive nitrogen intermediates suppress the primary immunologic response to Listeria. Journal of Immunology. 150:1993;2901-2908.
11. Guo Z. G., Johnson A. M. Genetic comparison ofNeospora caninum. Parasitology Research. 81:1995;365-370.
12. Haque S., Haque A., Kasper L. H. AToxoplasma gondii. Infection and Immunity. 63:1995;3442-3447.
13. Haque S., Khan I. A., Haque A., Kasper L. H. Impairment of the cellular immune response in acute murine toxoplasmosis: Regulation of interleukin 2 production and macrophage-mediated inhibitory effects. Infection and Immunity. 62:1994;2908-2916.
14. Howe D. K., Sibley L. D. Toxoplasma gondii. Journal of Infectious Diseases. 172:1995;1561-1566.
15. Hunter C. A., Candolfi E., Subauste C., Van Cleave V., Remington J. S. Studies on the role of interleukin-12 in acute murine toxoplasmosis. Immunology. 84:1995;16-20.
16. 3. Journal of Comparative Pathology. 113:1995;95-100.
17. Kasper L. H., Matsuura T., Khan I. A. IL-7 stimulates protective immunity in mice against the intracellular pathogen,Toxoplasma gondii. Journal of Immunology. 155:1995;4798-4804.
18. Khan I. A., Matsuura T., Kasper L. H. Interleukin-12 enhances murine survival against acute toxoplasmosis. Infection and Immunity. 62:1994;1639-1642.
19. Khan I. A., Matsuura T., Kasper L. H. IL-10 mediates immunosuppression following primary infection withToxoplasma gondii. Parasite Immunology. 17:1995;185-195.
20. Lindsay D. S., Dubey J. P. Infections in mice with tachyzoites and bradyzoites of Neospora caninum (Protozoa: Apicomplexa). Journal of Parasitology. 76:1990;410-413.
21. Lindsay D. S., Lenz S. D., Cole R. A., Dubey J. P., Blagburn B. L. Mouse model for central nervous systemNeospora caninum. Journal of Parasitology. 81:1995;313-315.
22. Marsh A. E., Barr B. C., Sverlow K., Ho M., Dubey J. P., Conrad P. A. Sequence analysis and comparison of ribosomal DNA from bovine Neospora to similar coccidial parasites. Journal of Parasitology. 81:1995;530-535.
23. Munday B. L., Dubey J. P., Mason R. W. Neospora caninum. Austrian Veterinary Journal. 67:1990;76-77.
24. Rockett K. A., Auburn M. M., Rockett A. J., Cowden W. B., Clark I. A. Possible role of nitric oxide in malarial immunosuppression. Parasite Immunology. 16:1994;243-249.
25. Sternberg J., McGuigan F. Nitric oxide mediates suppression of T cell responses in murineTrypanasoma brucei. European Journal of Immunology. 22:1992;2741-2748.