Insulin determines leptin responses during a glucose challenge in fed and fasted rats

International Journal of Obesity

Volumn 29, Issue 4, 2005, Pages 398-405

  Walker, C G ^a   Bryson, J M ^a   Bell Anderson, K S ^a   Hancock, D P ^a   Denyer, G S ^a   Caterson, I D ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Adipocyte; Glucose challenge; Insulin; Intracellular leptin; Ob expression

Indexed keywords

FATTY ACID; INSULIN; LEPTIN; MESSENGER RNA;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DIET RESTRICTION; EPIDIDYMIS FAT; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HORMONE RELEASE; HORMONE RESPONSE; INSULIN BLOOD LEVEL; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; NONHUMAN; NUTRITIONAL STATUS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DEPRESSION, CHEMICAL; EPIDIDYMIS; FASTING; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION; GLUCOSE; INJECTIONS, INTRAVENOUS; INSULIN; LEPTIN; MALE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIFIC PATHOGEN-FREE ORGANISMS;

ANIMALIA;

EID: 16244362368     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0802884     Document Type: Article

References (39)

1. Levy JR, Lesko J, Krieg Jr RJ, Adler RA, Stevens W. Leptin responses to glucose infusions in obesity-prone rats. Am J Physiol Endocrinol Metab 2000; 279: E1088-E1096.
2. Ahren B, Mansson S, Gingerich RL, Havel PJ. Regulation of plasma leptin in mice: influence of age, high-fat diet, and fasting. Am J Physiol Regul Integr Comp Physiol 1997; 273: R113-R120.
3. Bryson JM, Phuyal JL, Proctor DR, Blair SC, Caterson ID, Cooney GJ. Plasma insulin rise precedes elevation of ob mRNA expression and plasma leptin in gold thioglucose-obese mice. Am J Physiol Endocrinol Metab 1998; 276: E358-E364.
4. Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV. Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity. Proc Natl Acad Sci USA 1996; 93: 3434-3438.
5. Saladin R, De Vos P, Guerre-Millo M, Leturque A, Girard J, Staels B, Auwerx J. Transient increase in obese gene expression after food intake or insulin administration. Nature 1995; 377: 527-529.
6. Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B. The ob gene and insulin. A relationship leading to clues to the understanding of obesity. Diabetes 1995; 44: 1467-1470.
7. Patel BK, Koenig JI, Kaplan LM, Hooi SC. Increase in plasma leptin and Lep mRNA concentrations by food intake is dependent on insulin. Metabolism 1998; 47: 603-607.
8. Li H, Matheny M, Tumer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression. Am J Physiol Endocrinol Metab 1998; 275: E405-E411.
9. MacDougald OA, Hwang CS, Fan H, Lane MD. Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci USA 1995; 92: 9034-9037.
10. Levy JR, Gyarmati J, Lesko JM, Adler RA, Stevens W. Dual regulation of leptin secretion: intracellular energy and calcium dependence of regulated pathway. Am J Physiol Endocrinol Metab 2000; 278: E892-E901.
11. Mueller WM, Gregoire FM, Stanhope KL, Mobbs CV, Mizuno TM, Warden CH, Stern JS, Havel PJ. Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology 1998; 139: 551-558.
12. Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 1998; 393: 684-688.
13. Fain JN, Bahouth SW. Stimulation of leptin release by actinomycin D in rat adipocytes. Biochem Pharmacol 1998; 55: 1309-1314.
14. Russell CD, Petersen RN, Rao SP, Ricci MR, Prasad A, Zhang Y, Brolin RE, Fried SK. Leptin expression in adipose tissue from obese humans: depot-specific regulation by insulin and dexamethasone. Am J Physiol Endocrinol Metab 1998; 275: E507-E515.
15. Casabiell X, Pineiro V, De la Cruz LF, Gualillo O, Folgar L, Dieguez C, Casanueva FF. Dual effect of insulin on in vitro leptin secretion by adipose tissue. Biochem Biophys Res Commun 2000; 276: 477-482.
16. Bradley RL, Cheatham B. Regulation of ob gene expression and leptin secretion by insulin and dexamethasone in rat adipocytes. Diabetes 1999; 48: 272-278.
17. Rentsch J, Chiesi M. Regulation of ob gene mRNA levels in cultured adipocytes. FEBS lett 1996; 379: 55-59.
18. Shintani M, Nishimura H, Yonemitsu S, Masuzaki H, Ogawa Y, Hosoda K, Inoue G, Yoshimasa Y, Nakao K. Downregulation of leptin by free fatty acids in rat adipocytes: effects of triacsin C, palmitate, and 2-bromopalmitate. Metabolism 2000; 49: 326-330.
19. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS. Role of leptin in the neuroendocrine response to fasting. Nature 1996; 382: 250-252.
20. Flier JS, Maratos-Flier E. Obesity and the hypothalamus: novel peptides for new pathways. Cell 1998; 92: 437-440.
21. Russell CD, Ricci MR, Brolin RE, Magill E, Fried SK. Regulation of the leptin content of obese human adipose tissue. Am J Physiol Endocrinol Metab 2001; 280: E399-E404.
22. Pagano C, Englaro P, Granzotto M, Blum WF, Sagrillo E, Ferretti E, Federspil G, Vettor R. Insulin induces rapid changes of plasma leptin in lean but not in genetically obese (fa/fa) rats. Int J Obes Relat Metab Disord 1997; 21: 614-618.
23. Saad MF, Khan A, Sharma A, Michael R, Riad-Gabriel MG, Boyadjian R, Jinagouda SD, Steil GM, Kamdar V. Physiological insulinemia acutely modulates plasma leptin. Diabetes 1998; 47: 544-549.
24. Sivitz WI, Walsh S, Morgan D, Donohoue P, Haynes W, Leibel RL. Plasma leptin in diabetic and insulin-treated diabetic and normal rats. Metabolism 1998; 47: 584-591.
25. Fruehwald-Schultes B, Oltmanns KM, Kern W, Born J, Fehm HL, Peters A. The effect of experimentally induced insulin resistance on the leptin response to hyperinsulinaemia. Int J Obes Relat Metab Disord 2002; 26: 510-516.
26. Bryson JM, Cooney GJ, Wensley VR, Phuyal JL, Hew M, Denyer GS, Caterson ID. High-fat feeding alters the response of rat PDH complex to acute changes in glucose and insulin. Am J Physiol Endocrinol Metab 1995; 268: E752-E757.
27. Saggerson ED, Greenbaum AL. The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Biochem J 1970; 119: 221-242.
28. Kasuga M, Akanuma Y, Iwamoto Y, Kosaka K. Effects of fasting and refeeding of insulin receptors and glucose metabolism in rat adipocytes. Endocrinology 1977; 100: 1384-1390.
29. Sonnenberg GE, Krakower GR, Hoffmann RG, Maas DL, Hennes MM, Kissebah AH. Plasma leptin concentrations during extended fasting and graded glucose infusions: relationships with changes in glucose, insulin, and FFA. J Clin Endocrinol Metab 2001; 86: 4895-4900.
30. Trayhurn P, Thomas ME, Duncan JS, Rayner DV. Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice. FEBS Lett 1995; 368: 488-490.
31. Walker CG, Bryson JM, Phuyal JL, Caterson ID. Dietary modulation of circulating leptin levels: site-specific changes in fat deposition and ob mRNA expression. Horm Metab Res 2002; 34: 176-181.
32. Becker DJ, Ongemba LN, Brichard V, Henquin JC, Brichard SM. Diet- and diabetes-induced changes of ob gene expression in rat adipose tissue. FEBS Lett 1995; 371: 324-328.
33. Fain JN, Bahouth SW. Hormonal regulation of 18S RNA, leptin mRNA, and leptin release in adipocytes from hypothyroid rats. Metabolism 1998; 47: 1455-1461.
34. Barr VA, Malide D, Zarnowski MJ, Taylor SI, Cushman SW. Insulin stimulates both leptin secretion and production by rat white adipose tissue. Endocrinology 1997; 138: 4463-4472.
35. Turban S, Hainault I, Andre J, Ferre P, Quignard-Boulange A, Guerre-Millo M. Molecular and cellular mechanisms of adipose secretion: comparison of leptin and angiotensinogen. J Cell Biochem 2001; 82: 666-673.
36. Kirchgessner TG, Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Tumor necrosis factor-α contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J Clin Invest 1997; 100: 2777-2782.
37. Makimura H, Mizuno TM, Isoda F, Beasley J, Silverstein JH, Mobbs CV. Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression. BMC Physiol 2003; 3: 5.
38. Rayner DV, Trayhurn P. Regulation of leptin production: sympathetic nervous system interactions. J Mol Med 2001; 79: 8-20.
39. Ahren B. Diurnal variation in circulating leptin is dependent on gender, food intake and circulating insulin in mice. Acta Physiol Scand 2000; 169: 325-331.