TGF-β1 regulation in hepatocyte-NIH3T3 co-culture is important for the enhanced hepatocyte function in 3D microenvironment

Biotechnology and Bioengineering

Volumn 89, Issue 5, 2005, Pages 565-573

  Chia, Ser Mien ^a   Lin, Pao Chun ^a   Yu, Hanry ^a,b  

^a Clinical Research Centre   (Singapore)

^b INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

Cell cell interactions; Co culture; Hepatocytes; Posttranscriptional regulation; Transforming growth factor 1 activation

Indexed keywords

BIOASSAY; BIOLOGICAL MEMBRANES; DATA ACQUISITION; DRUG THERAPY; SYNTHESIS (CHEMICAL); TISSUE;

ANTIBODY; CELL-CELL INTERACTIONS; FUNCTIONAL ENHANCEMENTS; HEPATOCYTE FUNCTIONS;

CELL CULTURE;

CYTOCHROME P450 REDUCTASE; TRANSFORMING GROWTH FACTOR BETA1; CYTOCHROME P450 1A1; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL INTERACTION; CELL STRAIN 3T3; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG METABOLISM; EMBRYO; ENZYME ACTIVITY; ENZYME ASSAY; EXTRACELLULAR SPACE; GENE ACTIVATION; GENE CONTROL; GENETIC TRANSCRIPTION; IN VITRO STUDY; LIVER; LIVER CELL; MICROENCAPSULATION; MICROENVIRONMENT; MOUSE; NONHUMAN; RNA TRANSLATION; SEPARATION TECHNIQUE; SPHEROID CELL; TISSUE ENGINEERING; UPREGULATION; ANIMAL; BIOTECHNOLOGY; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FIBROBLAST; METABOLISM; METHODOLOGY; MULTICELLULAR SPHEROID; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME;

ANIMALS; BIOTECHNOLOGY; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CYTOCHROME P-450 CYP1A1; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FIBROBLASTS; HEPATOCYTES; MICE; NIH 3T3 CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPHEROIDS, CELLULAR; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 15944404223     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20372     Document Type: Article

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