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Volumn 90, Issue 3, 2005, Pages 1632-1638

Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in Asian and Caucasian men

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ESTRADIOL; GESTAGEN; LUTEINIZING HORMONE; TESTOSTERONE; ANTIFUNGAL AGENT; KETOCONAZOLE; SEX HORMONE BINDING GLOBULIN;

EID: 15944402122     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-1362     Document Type: Article
Times cited : (12)

References (74)
  • 1
    • 18244373474 scopus 로고    scopus 로고
    • Male fertility is compatible with an Arg(840)Cys substitution in the AR in a large Chinese family affected with divergent phenotypes of AR insensitivity syndrome
    • Chu J, Zhang R, Zhao Z, Zou W, Han Y, Qi Q, Zhang H, Wang JC, Tao S, Liu X, Luo Z 2002 Male fertility is compatible with an Arg(840)Cys substitution in the AR in a large Chinese family affected with divergent phenotypes of AR insensitivity syndrome. J Clin Endocrinol Metab 87:347-351
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 347-351
    • Chu, J.1    Zhang, R.2    Zhao, Z.3    Zou, W.4    Han, Y.5    Qi, Q.6    Zhang, H.7    Wang, J.C.8    Tao, S.9    Liu, X.10    Luo, Z.11
  • 2
    • 0032429676 scopus 로고    scopus 로고
    • Serum oestradiol and oestrogen-receptor gene polymorphism are associated with bone mineral density independently of serum testosterone in normal males
    • Oxf
    • Ongphiphadhanakul B, Rajatanavin R, Chanprasertyothin S, Piaseu N, Chailurkit L 1998 Serum oestradiol and oestrogen-receptor gene polymorphism are associated with bone mineral density independently of serum testosterone in normal males. Clin Endocrinol (Oxf) 49:803-809
    • (1998) Clin Endocrinol , vol.49 , pp. 803-809
    • Ongphiphadhanakul, B.1    Rajatanavin, R.2    Chanprasertyothin, S.3    Piaseu, N.4    Chailurkit, L.5
  • 3
    • 0036141602 scopus 로고    scopus 로고
    • Oestrogen receptors, receptor variants and oestrogen actions in the hypothalamic-pituitary axis
    • Shupnik MA 2002 Oestrogen receptors, receptor variants and oestrogen actions in the hypothalamic-pituitary axis. J Neuroendocrinol 14:85-94
    • (2002) J Neuroendocrinol , vol.14 , pp. 85-94
    • Shupnik, M.A.1
  • 6
    • 1842376911 scopus 로고    scopus 로고
    • Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility
    • Tapanainen JS, Aittomaki K, Min J, Vaskivuo T, Huhtaniemi IT 1997 Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nat Genet 15:205-206
    • (1997) Nat Genet , vol.15 , pp. 205-206
    • Tapanainen, J.S.1    Aittomaki, K.2    Min, J.3    Vaskivuo, T.4    Huhtaniemi, I.T.5
  • 7
    • 0023954666 scopus 로고
    • Contemporary aspects of discrete peak detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men
    • Urban RJ, Evans WS, Rogol AD, Kaiser DL, Johnson ML, Veldhuis JD 1988 Contemporary aspects of discrete peak detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men. Endocr Rev 9:3-37
    • (1988) Endocr Rev , vol.9 , pp. 3-37
    • Urban, R.J.1    Evans, W.S.2    Rogol, A.D.3    Kaiser, D.L.4    Johnson, M.L.5    Veldhuis, J.D.6
  • 8
    • 0002946128 scopus 로고    scopus 로고
    • Male hypothalamic-pituitary-gonadal axis
    • Yen SSC, Jaffe RB, Barbieri RL, eds. Philadelphia: WB Saunders
    • Veldhuis JD 1999 Male hypothalamic-pituitary-gonadal axis. In: Yen SSC, Jaffe RB, Barbieri RL, eds. Reproductive endocrinology. 4th ed. Philadelphia: WB Saunders; 622-631
    • (1999) Reproductive Endocrinology. 4th Ed. , pp. 622-631
    • Veldhuis, J.D.1
  • 9
    • 0029862979 scopus 로고    scopus 로고
    • Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. III. Higher 5 α-reductase activity in oligozoospermic men administered supraphysiological doses of testosterone
    • Anderson RA, Wallace AM, Wu FC 1996 Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. III. Higher 5 α-reductase activity in oligozoospermic men administered supraphysiological doses of testosterone. J Clin Endocrinol Metab 81:902-908
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 902-908
    • Anderson, R.A.1    Wallace, A.M.2    Wu, F.C.3
  • 10
    • 0029960780 scopus 로고    scopus 로고
    • Contraceptive efficacy of testosterone-induced azoospermia and oligozoospermia in normal men
    • World Health Organization 1996 Contraceptive efficacy of testosterone-induced azoospermia and oligozoospermia in normal men. Fertil Steril 65:821-829
    • (1996) Fertil Steril , vol.65 , pp. 821-829
  • 11
    • 0030917993 scopus 로고    scopus 로고
    • Progestin-androgen combination regimens for male contraception
    • Meriggiola MC, Bremner WJ 1997 Progestin-androgen combination regimens for male contraception. J Androl 18:240-244
    • (1997) J Androl , vol.18 , pp. 240-244
    • Meriggiola, M.C.1    Bremner, W.J.2
  • 12
    • 0028851197 scopus 로고
    • Factors in nonuniform induction of azoospermia by testosterone enanthate in normal men
    • World Health Organization Task Force on Methods for the Regulation of Male Fertility
    • Handelsman DJ, Farley TM, Peregoudov A, Waites GM 1995 Factors in nonuniform induction of azoospermia by testosterone enanthate in normal men. World Health Organization Task Force on Methods for the Regulation of Male Fertility. Fertil Steril 63:125-133
    • (1995) Fertil Steril , vol.63 , pp. 125-133
    • Handelsman, D.J.1    Farley, T.M.2    Peregoudov, A.3    Waites, G.M.4
  • 13
    • 0030778388 scopus 로고    scopus 로고
    • Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. V. Localization of higher 5 α-reductase activity to the reproductive tract in oligozoospermic men administered supraphysiological doses of testosterone
    • Anderson RA, Kelly RW, Wu FC 1997 Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. V. Localization of higher 5 α-reductase activity to the reproductive tract in oligozoospermic men administered supraphysiological doses of testosterone. J Androl 18:366-371
    • (1997) J Androl , vol.18 , pp. 366-371
    • Anderson, R.A.1    Kelly, R.W.2    Wu, F.C.3
  • 14
    • 0031764875 scopus 로고    scopus 로고
    • Stereological evaluation of human spermatogenesis after suppression by testosterone treatment: Heterogeneous pattern of spermatogenic impairment
    • Zhengwei Y, Wreford NG, Royce P, de Kretser DM, McLachlan RI 1998 Stereological evaluation of human spermatogenesis after suppression by testosterone treatment: heterogeneous pattern of spermatogenic impairment. J Clin Endocrinol Metab 83:1284-1291
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1284-1291
    • Zhengwei, Y.1    Wreford, N.G.2    Royce, P.3    De Kretser, D.M.4    McLachlan, R.I.5
  • 15
    • 0034748601 scopus 로고    scopus 로고
    • Daily testosterone and gonadotropin levels are similar in azoospermic and nonazoospermic normal men administered weekly testosterone: Implications for male contraceptive development
    • Amory JK, Anawalt BD, Bremner WJ, Matsumoto AM 2001 Daily testosterone and gonadotropin levels are similar in azoospermic and nonazoospermic normal men administered weekly testosterone: implications for male contraceptive development. J Androl 22:1053-1060
    • (2001) J Androl , vol.22 , pp. 1053-1060
    • Amory, J.K.1    Anawalt, B.D.2    Bremner, W.J.3    Matsumoto, A.M.4
  • 17
    • 0031791243 scopus 로고    scopus 로고
    • Graded testosterone infusions distinguish gonadotropin negative-feedback responsiveness in Asians and white men - A clinical research center study
    • Wang C, Berman N, Veldhuis JD, Der T, McDonald V, Steiner B, Swerdloff RS 1998 Graded testosterone infusions distinguish gonadotropin negative-feedback responsiveness in Asians and white men - a clinical research center study. J Clin Endocrinol Metab 83:870-876
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 870-876
    • Wang, C.1    Berman, N.2    Veldhuis, J.D.3    Der, T.4    McDonald, V.5    Steiner, B.6    Swerdloff, R.S.7
  • 18
    • 0006865192 scopus 로고    scopus 로고
    • Role of endogenous aromatase in testosterone's short-term feedback regulation of 24-hour LH, FSH, and GH release in young men
    • Atlanta, GA, Abstract 112
    • Schnorr J, Santen RJ, Veldhuis JD, Role of endogenous aromatase in testosterone's short-term feedback regulation of 24-hour LH, FSH, and GH release in young men. Proc Annual Meeting of the Society for Gynecologic Investigation, Atlanta, GA, 1999 (Abstract 112)
    • (1999) Proc Annual Meeting of the Society for Gynecologic Investigation
    • Schnorr, J.1    Santen, R.J.2    Veldhuis, J.D.3
  • 19
    • 2942640232 scopus 로고    scopus 로고
    • Testosterone metabolic clearance and production rates determined by stable isotope dilution/tandem mass spectrometry in normal men: Influence of ethnicity and age
    • Wang C, Catlin DH, Starcevic B, Leung A, DiStefano E, Lucas G, Hull L, Swerdloff RS 2004 Testosterone metabolic clearance and production rates determined by stable isotope dilution/tandem mass spectrometry in normal men: influence of ethnicity and age. J Clin Endocrinol Metab 89:2936-2941
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2936-2941
    • Wang, C.1    Catlin, D.H.2    Starcevic, B.3    Leung, A.4    DiStefano, E.5    Lucas, G.6    Hull, L.7    Swerdloff, R.S.8
  • 20
    • 0030945174 scopus 로고    scopus 로고
    • Neuroendocrine mechanisms by which selective Leydig-cell castration unleashes increased pulsatile LH release in the human: An experimental paradigm of short-term ketoconazole-induced hypoandrogenemia and deconvolution-estimated LH secretory enhancement
    • Veldhuis JD, Zwart AD, Iranmanesh A 1997 Neuroendocrine mechanisms by which selective Leydig-cell castration unleashes increased pulsatile LH release in the human: an experimental paradigm of short-term ketoconazole-induced hypoandrogenemia and deconvolution-estimated LH secretory enhancement. Am J Physiol 272:R464-R474
    • (1997) Am J Physiol , vol.272
    • Veldhuis, J.D.1    Zwart, A.D.2    Iranmanesh, A.3
  • 21
    • 0030872438 scopus 로고    scopus 로고
    • Disparate serum free testosterone concentrations and degrees of hypothalamo-pituitary-LH suppression are achieved by continuous versus pulsatile intravenous androgen replacement in men: A clinical experimental model of ketoconazole-induced reversible hypoandrogenemia with controlled testosterone add-back
    • Zwart A, Iranmanesh A, Veldhuis JD 1997 Disparate serum free testosterone concentrations and degrees of hypothalamo-pituitary-LH suppression are achieved by continuous versus pulsatile intravenous androgen replacement in men: a clinical experimental model of ketoconazole-induced reversible hypoandrogenemia with controlled testosterone add-back. J Clin Endocrinol Metab 82:2062-2069
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2062-2069
    • Zwart, A.1    Iranmanesh, A.2    Veldhuis, J.D.3
  • 22
    • 0034976485 scopus 로고    scopus 로고
    • Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous GnRH-stimulated LH and FSH secretion in young men
    • Schnorr JA, Bray MJ, Veldhuis JD 2001 Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous GnRH-stimulated LH and FSH secretion in young men. J Clin Endocrinol Metab 86:2600-2606
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2600-2606
    • Schnorr, J.A.1    Bray, M.J.2    Veldhuis, J.D.3
  • 23
    • 0026762786 scopus 로고
    • Attenuation of luteinizing hormone secretory burst amplitude is a proximate basis for the hypoandrogenism of healthy aging in men
    • Veldhuis JD, Urban RJ, Lizarralde G, Johnson ML, Iranmanesh A 1992 Attenuation of luteinizing hormone secretory burst amplitude is a proximate basis for the hypoandrogenism of healthy aging in men. J Clin Endocrinol Metab 75:52-58
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 52-58
    • Veldhuis, J.D.1    Urban, R.J.2    Lizarralde, G.3    Johnson, M.L.4    Iranmanesh, A.5
  • 24
    • 0028557257 scopus 로고
    • Differential responses of biologically active LH secretion in older versus young men to interruption of androgen negative feedback
    • Veldhuis JD, Urban RJ, Dufau ML 1994 Differential responses of biologically active LH secretion in older versus young men to interruption of androgen negative feedback. J Clin Endocrinol Metab 79:1763-1770
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1763-1770
    • Veldhuis, J.D.1    Urban, R.J.2    Dufau, M.L.3
  • 25
    • 0027450582 scopus 로고
    • Evidence for attenuation of hypothalamic GnRH impulse strength with preservation of gonadotropin-releasing hormone (GnRH) pulse frequency in men with chronic renal failure
    • Veldhuis JD, Wilkowski MJ, Urban RJ, Lizarralde G, Iranmanesh A, Bolton WK 1993 Evidence for attenuation of hypothalamic GnRH impulse strength with preservation of gonadotropin-releasing hormone (GnRH) pulse frequency in men with chronic renal failure. J Clin Endocrinol Metab 76:648-654
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 648-654
    • Veldhuis, J.D.1    Wilkowski, M.J.2    Urban, R.J.3    Lizarralde, G.4    Iranmanesh, A.5    Bolton, W.K.6
  • 26
    • 0032879225 scopus 로고    scopus 로고
    • Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig-cell) defects in the healthy aging male gonadotropic axis
    • Mulligan T, Iranmanesh A, Kerzner R, Demers LW, Veldhuis JD 1999 Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig-cell) defects in the healthy aging male gonadotropic axis. Eur J Endocrinol 141:257-266
    • (1999) Eur J Endocrinol , vol.141 , pp. 257-266
    • Mulligan, T.1    Iranmanesh, A.2    Kerzner, R.3    Demers, L.W.4    Veldhuis, J.D.5
  • 27
    • 0022447036 scopus 로고
    • Cluster analysis: A simple, versatile and robust algorithm for endocrine pulse detection
    • Veldhuis JD, Johnson ML 1986 Cluster analysis: a simple, versatile and robust algorithm for endocrine pulse detection. Am J Physiol 250:E486-E493
    • (1986) Am J Physiol , vol.250
    • Veldhuis, J.D.1    Johnson, M.L.2
  • 28
    • 0035187808 scopus 로고    scopus 로고
    • Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male
    • Mulligan T, Iranmanesh A, Veldhuis JD 2001 Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male. J Clin Endocrinol Metab 86:5547-5553
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5547-5553
    • Mulligan, T.1    Iranmanesh, A.2    Veldhuis, J.D.3
  • 29
    • 0024391664 scopus 로고
    • Biophysical modeling of the sensitivity and positive accuracy of detecting episodic endocrine signals
    • Urban RJ, Johnson ML, Veldhuis JD 1989 Biophysical modeling of the sensitivity and positive accuracy of detecting episodic endocrine signals. Am J Physiol 257:E88-E94
    • (1989) Am J Physiol , vol.257
    • Urban, R.J.1    Johnson, M.L.2    Veldhuis, J.D.3
  • 30
    • 0024516147 scopus 로고
    • In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection: I. The LH pulse signal
    • Urban RJ, Johnson ML, Veldhuis JD 1989 In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection: I. The LH pulse signal. Endocrinology 124:2541-2547
    • (1989) Endocrinology , vol.124 , pp. 2541-2547
    • Urban, R.J.1    Johnson, M.L.2    Veldhuis, J.D.3
  • 31
    • 0026015905 scopus 로고
    • Approximate entropy as a measure of system complexity
    • Pincus SM 1991 Approximate entropy as a measure of system complexity. Proc Natl Acad Sci USA 88:2297-2301
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2297-2301
    • Pincus, S.M.1
  • 33
    • 0000488177 scopus 로고
    • Quantifying complexity and regularity of neurobiological systems
    • Pincus SM 1995 Quantifying complexity and regularity of neurobiological systems. Methods Neurosci 28:336-363
    • (1995) Methods Neurosci , vol.28 , pp. 336-363
    • Pincus, S.M.1
  • 34
    • 0030450771 scopus 로고    scopus 로고
    • Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males
    • Pincus SM, Mulligan T, Iranmanesh A, Gheorghiu S, Godschalk M, Veldhuis JD 1996 Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males. Proc Natl Acad Sci USA 93:14100-14105
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14100-14105
    • Pincus, S.M.1    Mulligan, T.2    Iranmanesh, A.3    Gheorghiu, S.4    Godschalk, M.5    Veldhuis, J.D.6
  • 36
    • 0035665001 scopus 로고    scopus 로고
    • Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion
    • Veldhuis JD, Johnson ML, Veldhuis OL, Straume M, Pincus S 2001 Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion. Am J Physiol 281:R1975-R1985
    • (2001) Am J Physiol , vol.281
    • Veldhuis, J.D.1    Johnson, M.L.2    Veldhuis, O.L.3    Straume, M.4    Pincus, S.5
  • 38
    • 0032041942 scopus 로고    scopus 로고
    • Orderliness of hormone release patterns: A complementary measure to conventional pulsatile and circadian analyses
    • Veldhuis JD, Pincus SM 1998 Orderliness of hormone release patterns: a complementary measure to conventional pulsatile and circadian analyses. Eur J Endocrinol 138:358-362
    • (1998) Eur J Endocrinol , vol.138 , pp. 358-362
    • Veldhuis, J.D.1    Pincus, S.M.2
  • 39
    • 0024405530 scopus 로고
    • Amplitude modulation of a burst-like mode of cortisol secretion subserves the circadian glucocorticoid rhythm in man
    • Veldhuis JD, Iranmanesh A, Lizarralde G, Johnson ML 1989 Amplitude modulation of a burst-like mode of cortisol secretion subserves the circadian glucocorticoid rhythm in man. Am J Physiol 257:E6-E14
    • (1989) Am J Physiol , vol.257
    • Veldhuis, J.D.1    Iranmanesh, A.2    Lizarralde, G.3    Johnson, M.L.4
  • 40
    • 0025696237 scopus 로고
    • Twenty-four hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts
    • Veldhuis JD, Iranmanesh A, Johnson ML, Lizarralde G 1990 Twenty-four hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts. J Clin Endocrinol Metab 71:1616-1623
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 1616-1623
    • Veldhuis, J.D.1    Iranmanesh, A.2    Johnson, M.L.3    Lizarralde, G.4
  • 42
    • 0023188313 scopus 로고
    • Sustained inhibitory actions of a potent antagonist of gonadotropin-releasing hormone in postmenopausal women
    • Davis MR, Veldhuis JD, Rogol AD, Dufau ML, Catt KJ 1987 Sustained inhibitory actions of a potent antagonist of gonadotropin-releasing hormone in postmenopausal women. J Clin Endocrinol Metab 64:1268-1274
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 1268-1274
    • Davis, M.R.1    Veldhuis, J.D.2    Rogol, A.D.3    Dufau, M.L.4    Catt, K.J.5
  • 44
    • 0024523047 scopus 로고
    • The nature of the gonadotropin-releasing hormone stimulus-luteinizing hormone secretory response of human gonadotrophs in vivo
    • Veldhuis JD, O'Dea LS, Johnson ML 1989 The nature of the gonadotropin-releasing hormone stimulus-luteinizing hormone secretory response of human gonadotrophs in vivo. J Clin Endocrinol Metab 68:661-670
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 661-670
    • Veldhuis, J.D.1    O'Dea, L.S.2    Johnson, M.L.3
  • 45
    • 0025047184 scopus 로고
    • Operating behavior of dual or multiple endocrine pulse generators
    • Veldhuis JD, Lassiter AB, Johnson ML 1990 Operating behavior of dual or multiple endocrine pulse generators. Am J Physiol 259:E351-E361
    • (1990) Am J Physiol , vol.259
    • Veldhuis, J.D.1    Lassiter, A.B.2    Johnson, M.L.3
  • 46
    • 0023277114 scopus 로고
    • The significance of small pulses of gonadotropin-releasing hormone
    • Clarke IJ, Cummins JT 1987 The significance of small pulses of gonadotropin-releasing hormone. J Endocrinol 113:413-418
    • (1987) J Endocrinol , vol.113 , pp. 413-418
    • Clarke, I.J.1    Cummins, J.T.2
  • 47
    • 0035665125 scopus 로고    scopus 로고
    • Disruption of the hypothalamic luteinizing-hormone pulsing mechanism in aging men
    • Keenan DM, Veldhuis JD 2001 Disruption of the hypothalamic luteinizing-hormone pulsing mechanism in aging men. Am J Physiol 281:R1917-R1924
    • (2001) Am J Physiol , vol.281
    • Keenan, D.M.1    Veldhuis, J.D.2
  • 48
    • 0022669377 scopus 로고
    • Hypogonadotropic disorders in men and women: Diagnosis and therapy with pulsatile gonadotropin-releasing hormone
    • Santoro N, Filicori M, Crowley Jr WF 1986 Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone. Endocr Rev 7:11-23
    • (1986) Endocr Rev , vol.7 , pp. 11-23
    • Santoro, N.1    Filicori, M.2    Crowley Jr., W.F.3
  • 49
    • 0034968016 scopus 로고    scopus 로고
    • Hypothesis testing of the aging male gonadal axis via a biomathematical construct
    • Keenan DM, Veldhuis JD 2001 Hypothesis testing of the aging male gonadal axis via a biomathematical construct. Am J Physiol 280:R1755-R1771
    • (2001) Am J Physiol , vol.280
    • Keenan, D.M.1    Veldhuis, J.D.2
  • 50
    • 0035095288 scopus 로고    scopus 로고
    • Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men
    • Veldhuis JD, Zwart A, Mulligan T, Iranmanesh A 2001 Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men. J Clin Endocrinol Metab 86:529-535
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 529-535
    • Veldhuis, J.D.1    Zwart, A.2    Mulligan, T.3    Iranmanesh, A.4
  • 51
    • 0034749483 scopus 로고    scopus 로고
    • Androgen suppression of GnRH-stimulated rat LH β gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region
    • Curtin D, Jenkins S, Farmer N, Anderson AC, Haisenleder DJ, Rissman E, Wilson EM, Shupnik MA 2001 Androgen suppression of GnRH-stimulated rat LH β gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region. Mol Endocrinol 15:1906-1917
    • (2001) Mol Endocrinol , vol.15 , pp. 1906-1917
    • Curtin, D.1    Jenkins, S.2    Farmer, N.3    Anderson, A.C.4    Haisenleder, D.J.5    Rissman, E.6    Wilson, E.M.7    Shupnik, M.A.8
  • 52
    • 0034824440 scopus 로고    scopus 로고
    • AR suppresses transcription of the LH β subunit by interacting with steroidogenic factor-1
    • Jorgensen JS, Nilson JH 2001 AR suppresses transcription of the LH β subunit by interacting with steroidogenic factor-1. Mol Endocrinol 15:1505-1516
    • (2001) Mol Endocrinol , vol.15 , pp. 1505-1516
    • Jorgensen, J.S.1    Nilson, J.H.2
  • 53
    • 0024594063 scopus 로고
    • Divergent effects of estradiol on gonadotropin gene transcription in pituitary fragments
    • Shupnik MA, Gharib SD, Chin WW 1989 Divergent effects of estradiol on gonadotropin gene transcription in pituitary fragments. Mol Endocrinol 3:474-480
    • (1989) Mol Endocrinol , vol.3 , pp. 474-480
    • Shupnik, M.A.1    Gharib, S.D.2    Chin, W.W.3
  • 54
    • 0023949309 scopus 로고
    • Estrogen suppresses rat gonadotropin gene transcription in vivo
    • Shupnik MA, Gharib SD, Chin WW 1988 Estrogen suppresses rat gonadotropin gene transcription in vivo. Endocrinology 122:1842-1846
    • (1988) Endocrinology , vol.122 , pp. 1842-1846
    • Shupnik, M.A.1    Gharib, S.D.2    Chin, W.W.3
  • 55
    • 0035955883 scopus 로고    scopus 로고
    • Identification of negative and positive estrogen response elements in human GnRH upstream promoter in the placental JEG-3 cells
    • Chen Z, Zheng H, Dong KW 2001 Identification of negative and positive estrogen response elements in human GnRH upstream promoter in the placental JEG-3 cells. Mol Cell Endocrinol 184:125-134
    • (2001) Mol Cell Endocrinol , vol.184 , pp. 125-134
    • Chen, Z.1    Zheng, H.2    Dong, K.W.3
  • 56
    • 0033237619 scopus 로고    scopus 로고
    • Estrogen directly represses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-α (ERα)- And ERβ-expressing GT1-7 GnRH neurons
    • Roy D, Angelini NL, Belsham DD 1999 Estrogen directly represses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-α (ERα)- and ERβ-expressing GT1-7 GnRH neurons. Endocrinology 140:5045-5053
    • (1999) Endocrinology , vol.140 , pp. 5045-5053
    • Roy, D.1    Angelini, N.L.2    Belsham, D.D.3
  • 57
    • 0034827697 scopus 로고    scopus 로고
    • Oestrogen receptor β-immunoreactivity in gonadotropin releasing hormone-expressing neurones: Regulation by oestrogen
    • Kallo I, Butler JA, Barkovics-Kallo M, Goubillon ML, Coen CW 2001 Oestrogen receptor β-immunoreactivity in gonadotropin releasing hormone-expressing neurones: regulation by oestrogen. J Neuroendocrinol 13:741-748
    • (2001) J Neuroendocrinol , vol.13 , pp. 741-748
    • Kallo, I.1    Butler, J.A.2    Barkovics-Kallo, M.3    Goubillon, M.L.4    Coen, C.W.5
  • 58
    • 0034841584 scopus 로고    scopus 로고
    • Significant population variation in adult male height associated with the Y chromosome and the aromatase gene
    • Ellis JA, Stebbing M, Harrap SB 2001 Significant population variation in adult male height associated with the Y chromosome and the aromatase gene. J Clin Endocrinol Metab 86:4147-4150
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4147-4150
    • Ellis, J.A.1    Stebbing, M.2    Harrap, S.B.3
  • 61
    • 0344867024 scopus 로고    scopus 로고
    • Evidence for oestrogen receptor α-immunoreactivity in gonadotrophin-releasing hormone-expressing neurones
    • Butler JA, Sjoberg M, Coen CW 1999 Evidence for oestrogen receptor α-immunoreactivity in gonadotrophin-releasing hormone-expressing neurones. J Neuroendocrinol 11:331-335
    • (1999) J Neuroendocrinol , vol.11 , pp. 331-335
    • Butler, J.A.1    Sjoberg, M.2    Coen, C.W.3
  • 62
    • 0033303528 scopus 로고    scopus 로고
    • Detection of estrogen receptor α and β messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons
    • Skynner MJ, Sim JA, Herbison AE 1999 Detection of estrogen receptor α and β messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons. Endocrinology 140:5195-5201
    • (1999) Endocrinology , vol.140 , pp. 5195-5201
    • Skynner, M.J.1    Sim, J.A.2    Herbison, A.E.3
  • 64
    • 0031788043 scopus 로고    scopus 로고
    • Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-α knockout mice
    • Lindzey J, Wetsel WC, Couse JF, Stoker T, Cooper R, Korach KS 1998 Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-α knockout mice. Endocrinology 139:4092-4101
    • (1998) Endocrinology , vol.139 , pp. 4092-4101
    • Lindzey, J.1    Wetsel, W.C.2    Couse, J.F.3    Stoker, T.4    Cooper, R.5    Korach, K.S.6
  • 65
    • 0034456509 scopus 로고    scopus 로고
    • Detection of estrogen receptor-β messenger ribonucleic acid and 125I-estrogen binding sites in luteinizing hormone-releasing hormone neurons of the rat brain
    • Hrabovszky E, Shughrue PJ, Merchenthaler I, Hajszan T, Carpenter CD, Liposits Z, Petersen SL 2000 Detection of estrogen receptor-β messenger ribonucleic acid and 125I-estrogen binding sites in luteinizing hormone-releasing hormone neurons of the rat brain. Endocrinology 141:3506-3509
    • (2000) Endocrinology , vol.141 , pp. 3506-3509
    • Hrabovszky, E.1    Shughrue, P.J.2    Merchenthaler, I.3    Hajszan, T.4    Carpenter, C.D.5    Liposits, Z.6    Petersen, S.L.7
  • 66
    • 0032746919 scopus 로고    scopus 로고
    • Estrogen receptor-mediated repression of gonadotropin-releasing hormone (gnRH) promoter activity in transfected CHO-K1 cells
    • Chen ZG, Yu KL, Zheng HM, Dong KW 1999 Estrogen receptor-mediated repression of gonadotropin-releasing hormone (gnRH) promoter activity in transfected CHO-K1 cells. Mol Cell Endocrinol 158:131-142
    • (1999) Mol Cell Endocrinol , vol.158 , pp. 131-142
    • Chen, Z.G.1    Yu, K.L.2    Zheng, H.M.3    Dong, K.W.4
  • 67
    • 0029874527 scopus 로고    scopus 로고
    • Evidence for estrogen receptor-mediated regulation of human gonadotropin-releasing hormone promoter activity in human placental cells
    • Dong KW, Chen ZG, Cheng KW, Yu KL 1996 Evidence for estrogen receptor-mediated regulation of human gonadotropin-releasing hormone promoter activity in human placental cells. Mol Cell Endocrinol 117:241-246
    • (1996) Mol Cell Endocrinol , vol.117 , pp. 241-246
    • Dong, K.W.1    Chen, Z.G.2    Cheng, K.W.3    Yu, K.L.4
  • 68
    • 0026766885 scopus 로고
    • Estrogen negatively regulates rat gonadotropin releasing hormone (rGnRH) promoter activity in transfected placental cells
    • Wierman ME, Kepa JK, Sun W, Gordon DF, Wood WM 1992 Estrogen negatively regulates rat gonadotropin releasing hormone (rGnRH) promoter activity in transfected placental cells. Mol Cell Endocrinol 86:1-10
    • (1992) Mol Cell Endocrinol , vol.86 , pp. 1-10
    • Wierman, M.E.1    Kepa, J.K.2    Sun, W.3    Gordon, D.F.4    Wood, W.M.5
  • 71
    • 0032572929 scopus 로고    scopus 로고
    • Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency
    • Bilezikian JP, Morishima A, Bell J, Grumbach MM 1998 Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N Engl J Med 339:599-603
    • (1998) N Engl J Med , vol.339 , pp. 599-603
    • Bilezikian, J.P.1    Morishima, A.2    Bell, J.3    Grumbach, M.M.4
  • 72
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female sibling caused by a novel mutation and the physiological role of estrogen
    • Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K 1995 Aromatase deficiency in male and female sibling caused by a novel mutation and the physiological role of estrogen. J Clin Endocrinol Metab 80:3689-3698
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3    Fisher, C.4    Qin, K.5
  • 73
    • 0021689590 scopus 로고
    • Inhibition of aromatization stimulates luteinizing hormone and testosterone secretion in adult male rhesus monkeys
    • Ellinwood WE, Hess DL, Roselli CE, Spies HG, Resko JA 1984 Inhibition of aromatization stimulates luteinizing hormone and testosterone secretion in adult male rhesus monkeys. J Clin Endocrinol Metab 59:1088-1096
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 1088-1096
    • Ellinwood, W.E.1    Hess, D.L.2    Roselli, C.E.3    Spies, H.G.4    Resko, J.A.5
  • 74
    • 0036078456 scopus 로고    scopus 로고
    • Pituitary function in a man with congenital aromatase deficiency: Effect of different doses of transdermal E2 on basal and stimulated pituitary hormones
    • Rochira V, Balestrieri A, Faustini-Fustini M, Borgato S, Beck-Peccoz P, Carani C 2002 Pituitary function in a man with congenital aromatase deficiency: effect of different doses of transdermal E2 on basal and stimulated pituitary hormones. J Clin Endocrinol Metab 87:2857-2862
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2857-2862
    • Rochira, V.1    Balestrieri, A.2    Faustini-Fustini, M.3    Borgato, S.4    Beck-Peccoz, P.5    Carani, C.6


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