Nucleic acid drugs: A novel approach

African Journal of Biotechnology

Volumn 3, Issue 12, 2004, Pages 662-666

  Jarald, Edwin ^a   Edwin, Sheeja ^a   Dubey, Pawan ^a   Ajay Tiwari, A ^a   Thakre, Vinod ^b  

^a B R NAHATA COLLEGE OF PHARMACY   (India)

^b Smriti College of Pharmaceutical Education   (India)

Author keywords

Antisense oligonucleotides; Aptamers; Ribozymes

Indexed keywords

MESSENGER RNA; NUCLEOTIDE DERIVATIVE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; RIBOZYME;

AMINO ACID SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; GENE EXPRESSION; MEDICAL RESEARCH; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; REVIEW; RNA INTERFERENCE;

EID: 15744401460     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (29)

1. Amarzguioui M, Holen T, Babaie E, Prydz H (2003). Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res. 31: 589-595.
2. Bennett CF, Cowsert LM (1999). Antisense oligonucleotides as a tool for gene functionalization and target validation. Biochem. Biophys. Acta. 1489: 19-30.
3. Beigelman L, McSwiggen JA, Draper KG, Gonzalez C, Jensen K, Karpeisky AM, Modak AS, Matulic AJ, Direnzo AB, Haeberli P, Sweedler D, Tracz D, Grimm S, Wincott FE, Thackaray VG, Usman N (1995). Chemical modification of hammer head ribozymes. J. Biol. Chem. 270: 25702-25708.
4. Brown DA, Kang SH, Gryaznov SM, DeDionisio L, Heidenreich O, Sullivan S, Xu X, Neerenberg MI (1994). Effects of phosphorothioate modification of oligodeoxynucleotides on specific protein binding. J. Biol. Chem. 43: 26801-26805.
5. Cech TR, Zaug AJ, Grabowski PJ (1981). In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell 27: 487-296.
6. Crooke ST, Lemonidis KM, Neilson L, Griffey R, Lesnik EA, Monia BP (1995). Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes. Biochem. J. 312: 599-608.
7. Damha MJ, Wilds CJ, Noronha A, Bruckner I, Borkow G, Arion D, Parniak MA (1998). Hybrids of RNA and arabinonucleic acids (ANA and FANA) are substrates of ribonuclease HJ Am. Chem. Soc. 120: 12976-12977.
8. Daryl KG (1993). Nucleic Acid structure and function, In Harpers Biochemistry, 23rd edition, Appleton and lange publication, Connecticut, pp. 378.
9. Eckstein F (2000). Phosphorothioate oligonucleotides: What is their origin and what is unique about them? Antisense Nucleic Acids Drug Dev. 10: 117-121.
10. Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T (2001). Duplexes of 21-nucleotide RNAs mediate RNA iterference in cultured mammalian cells. Nature 411: 494-498.
11. Ellington AD, Szostak JW (1990). In vitro selection of RNA molecules that bind specific ligands. Nature 346: 818-822.
12. Ess KC, Hutton JJ, Aronow BJ (1994). Double-strande phosphorothioate oilgonucleotide modultion of gene expression, Ann. New York Acad. Sci. 716: 321-332.
13. Fire A, Xu SQ, Montgomery MK, Kostas SA, Driver SE, Mello CC (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
14. Guerrier TC, Gardiner K, Marsh T, Pace N, Altman S (1983). The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 35: 849-857.
15. Gryaznov S, Chen JK (1994). Oligodeoxyribonucleotide N3' P5' phosphoroamidates (NPs): synthesis and hybridization properties. J. Am. Chem. Soc. 116: 3143-3144.
16. Hanvey CJ, Peter JN, Babiss EL (1992). Antisense and antigene properties of peptide nucleic acids. Science 258: 1481-1485.
17. Haseloff J, Gerlach WL (1988). Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature 334: 585-591.
18. Koshkin AA, Rajwanshi VK, Wengel J (1998). Novel convenient synthesis of LNA [2.2.1] bicyclo nucleosides. Tetrahedron Lett. 39: 4381-4384.
19. Levin AA (1999). A review of issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochem. Biophys. Acta. 1489: 69-84.
20. Matsukura M, Shinozuka K, Zon G, Mitsuya H, Reitz M, Cohen JS, Broder S (1987). Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus. Proc. Natl. Acad. Sci. 84: 7706-7719.
21. Nielsen PE (1999). Antisense properties of peptide nucleic acid. Methods Enzymol. 313: 156-164.
22. Phillips MI and Zhang YC (2000). Basic principles of using antisense oligonucleotides in vivo. Methods Enzymol. 313: 46-56.
23. Riordan, Michel L, John C (1991). Oligonucleotide based Therapeutics. Nature 350: 442-443.
24. Roy C (1993). Inhibition of gene transcription by purine rich triplex forming oligodeoxy ribonucleotides. Nucleic Acids Res. 21: 2845-2852.
25. Stein CA (2001). The experimental use of antisense oligonucleotide: a guide for the perplexed. J. Clin. Invest. 108: 641-644.
26. Uhlenbeck OC (1987). A small catalytic oligoribonucleotide. Nature 328: 596-600.
27. Vyas SP, Dixit VK (1998). In Pharmaceutical Biotecnology, 1st edition, CBS publishers and distributers, New Delhi, pp. 311.
28. Yu JY, DeRuiter SL, Turner DL (2002) RNA interference by expression of short interferencing and hair pin RNAs in mammalian cells. Proc. Natl. Acad. Sci. 99: 6047-6052.
29. Zamecnik PC, Stephenson ML (1978) Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. 75: 280-284.