-
2
-
-
17144436887
-
Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog
-
B. Adams, A. Chan, H. Callahan, C. Siwak, D. Tapp, C. Ikeda-Douglas, P. Atkinson, E. Head, C.W. Cotman, and N.W. Milgram Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog Behav. Brain Res. 108 2000 47 56
-
(2000)
Behav. Brain Res.
, vol.108
, pp. 47-56
-
-
Adams, B.1
Chan, A.2
Callahan, H.3
Siwak, C.4
Tapp, D.5
Ikeda-Douglas, C.6
Atkinson, P.7
Head, E.8
Cotman, C.W.9
Milgram, N.W.10
-
3
-
-
0031202243
-
Selegiline and vitamin e in Alzheimer's disease
-
A. Adelman Selegiline and vitamin E in Alzheimer's disease J. Fam. Pract. 45 1997 98 100
-
(1997)
J. Fam. Pract.
, vol.45
, pp. 98-100
-
-
Adelman, A.1
-
4
-
-
0034090510
-
Selegiline treatment and the extent of degenerative changes in brain tissue of patients with Alzheimer's disease
-
I. Alafuzoff, S. Helisalmi, E.H. Heinonen, K. Reinikainen, M. Hallikainen, H. Soininen, and K. Koivisto Selegiline treatment and the extent of degenerative changes in brain tissue of patients with Alzheimer's disease Eur. J. Clin. Pharmacol. 55 2000 815 819
-
(2000)
Eur. J. Clin. Pharmacol.
, vol.55
, pp. 815-819
-
-
Alafuzoff, I.1
Helisalmi, S.2
Heinonen, E.H.3
Reinikainen, K.4
Hallikainen, M.5
Soininen, H.6
Koivisto, K.7
-
5
-
-
4544305971
-
Dose-specific effects of scopolamine on canine cognition: Impairment of visuospatial memory, but not visuospatial discrimination
-
J.A. Araujo, A.D.F. Chan, L.L. Winka, P.A. Seymour, and N.W. Milgram Dose-specific effects of scopolamine on canine cognition: impairment of visuospatial memory, but not visuospatial discrimination Psychopharmacology 175 2004 92 98
-
(2004)
Psychopharmacology
, vol.175
, pp. 92-98
-
-
Araujo, J.A.1
Chan, A.D.F.2
Winka, L.L.3
Seymour, P.A.4
Milgram, N.W.5
-
6
-
-
0034102796
-
Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs
-
B.Y. Azizeh, E. Head, M.A. Ibrahim, R. Torp, A.J. Tenner, R.C. Kim, I.T. Lott, and C.W. Cotman Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs Exp. Neurol. 163 2000 111 122
-
(2000)
Exp. Neurol.
, vol.163
, pp. 111-122
-
-
Azizeh, B.Y.1
Head, E.2
Ibrahim, M.A.3
Torp, R.4
Tenner, A.J.5
Kim, R.C.6
Lott, I.T.7
Cotman, C.W.8
-
7
-
-
0027183289
-
Chronic effects of monoamine oxidase-B inhibitors on the behaviour of aged mice
-
A.J. Barber, P.H. Yu, and A.A. Boulton Chronic effects of monoamine oxidase-B inhibitors on the behaviour of aged mice Life Sci. 53 1993 739 747
-
(1993)
Life Sci.
, vol.53
, pp. 739-747
-
-
Barber, A.J.1
Yu, P.H.2
Boulton, A.A.3
-
8
-
-
0018690072
-
Physostigmine and recent memory: Effects in young and aged nonhuman primates
-
R.T. Bartus Physostigmine and recent memory: effects in young and aged nonhuman primates Science 206 4422 1979 1087 1089
-
(1979)
Science
, vol.206
, Issue.4422
, pp. 1087-1089
-
-
Bartus, R.T.1
-
9
-
-
0034125843
-
On neurodegenerative diseases, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis
-
R.T. Bartus On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis Exp. Neurol. 163 2000 495 529
-
(2000)
Exp. Neurol.
, vol.163
, pp. 495-529
-
-
Bartus, R.T.1
-
10
-
-
0024157910
-
Tetrahydroaminoacridine, 3,4 diaminopyridine and physostigmine: Direct comparison of effects on memory in aged primates
-
R.T. Bartus, and R.L. Dean Tetrahydroaminoacridine, 3,4 diaminopyridine and physostigmine: direct comparison of effects on memory in aged primates Neurobiol. Aging 9 4 1988 351 356
-
(1988)
Neurobiol. Aging
, vol.9
, Issue.4
, pp. 351-356
-
-
Bartus, R.T.1
Dean, R.L.2
-
11
-
-
0019972810
-
The cholinergic hypothesis of geriatric memory dysfunction
-
R.T. Bartus, R.L.I. Dean, B. Beer, and A.S. Lippa The cholinergic hypothesis of geriatric memory dysfunction Science 217 1982 408 414
-
(1982)
Science
, vol.217
, pp. 408-414
-
-
Bartus, R.T.1
Dean, R.L.I.2
Beer, B.3
Lippa, A.S.4
-
12
-
-
0036342754
-
Improvement of learning processes following chronic systemic administration of modafinil in mice
-
D. Beracochea, A. Celerier, N. Borde, M. Valleau, M. Peres, and C. Pierard Improvement of learning processes following chronic systemic administration of modafinil in mice Pharmacol. Biochem. Behav. 73 3 2002 723 728
-
(2002)
Pharmacol. Biochem. Behav.
, vol.73
, Issue.3
, pp. 723-728
-
-
Beracochea, D.1
Celerier, A.2
Borde, N.3
Valleau, M.4
Peres, M.5
Pierard, C.6
-
13
-
-
18344399075
-
Selegiline for Alzheimer's disease
-
[update of Cochrane Database Syst Rev. 2000; (2): CD000442; PMID: 10796544]. [Review] [59refs]
-
Birks, J., Flicker L., 2003. Selegiline for Alzheimer's disease. [update of Cochrane Database Syst Rev. 2000; (2): CD000442; PMID: 10796544]. [Review] [59refs] Cochrane Database of Systematic Reviews. (1): CD000442.
-
(2003)
Cochrane Database of Systematic Reviews
, Issue.1
-
-
Birks, J.1
Flicker, L.2
-
14
-
-
0025873274
-
Improvement of cognitive function by MAO-B inhibitor l-deprenyl in aged rats
-
R. Brandeis, M. Sapir, Y. Kapon, G. Borelli, S. Cadel, and B. Valsecchi Improvement of cognitive function by MAO-B inhibitor l-deprenyl in aged rats Pharmacol. Biochem. Behav. 39 1991 297 304
-
(1991)
Pharmacol. Biochem. Behav.
, vol.39
, pp. 297-304
-
-
Brandeis, R.1
Sapir, M.2
Kapon, Y.3
Borelli, G.4
Cadel, S.5
Valsecchi, B.6
-
15
-
-
0033903430
-
Development of a protocol for studying object recognition memory in the dog
-
H. Callahan, C. Ikeda-Douglas, E. Head, C.W. Cotman, and N.W. Milgram Development of a protocol for studying object recognition memory in the dog Prog. Neuro-Psychopharmacol. Biol. Psychiatry 24 2000 693 707
-
(2000)
Prog. Neuro-Psychopharmacol. Biol. Psychiatry
, vol.24
, pp. 693-707
-
-
Callahan, H.1
Ikeda-Douglas, C.2
Head, E.3
Cotman, C.W.4
Milgram, N.W.5
-
16
-
-
0002601508
-
A noncomparative open-label study evaluating the effect of selegiline hydrochloride in a clinical setting
-
S. Campbell, A. Trettien, and B. Kozan A noncomparative open-label study evaluating the effect of selegiline hydrochloride in a clinical setting Vet. Ther. 2 1 2001 24 39
-
(2001)
Vet. Ther.
, vol.2
, Issue.1
, pp. 24-39
-
-
Campbell, S.1
Trettien, A.2
Kozan, B.3
-
17
-
-
0035999629
-
Visuospatial impairments in aged canines (Canis familiaris): The role of cognitive-behavioral flexibility
-
A.D. Chan, P.M. Nippak, H. Murphey, C.J. Ikeda-Douglas, B. Muggenburg, E. Head, C.W. Cotman, and N.W. Milgram Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility Behav. Neurosci. 116 3 2002 443 454
-
(2002)
Behav. Neurosci.
, vol.116
, Issue.3
, pp. 443-454
-
-
Chan, A.D.1
Nippak, P.M.2
Murphey, H.3
Ikeda-Douglas, C.J.4
Muggenburg, B.5
Head, E.6
Cotman, C.W.7
Milgram, N.W.8
-
18
-
-
3042567016
-
Long term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): Randomised double-blind trial
-
C. Courtney, D. Farrell, R. Gray, R. Hills, L. Lynch, E. Sellwood, S. Edwards, W. Hardyman, J. Raftery, P. Crome, C. Lendon, H. Shaw, and P. Bentham Long term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial Lancet 363 2004 2105 2115
-
(2004)
Lancet
, vol.363
, pp. 2105-2115
-
-
Courtney, C.1
Farrell, D.2
Gray, R.3
Hills, R.4
Lynch, L.5
Sellwood, E.6
Edwards, S.7
Hardyman, W.8
Raftery, J.9
Crome, P.10
Lendon, C.11
Shaw, H.12
Bentham, P.13
-
19
-
-
0030013083
-
Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine
-
B.J. Cummings, E. Head, A.J. Afagh, N.W. Milgram, and C.W. Cotman Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine Neurobiol. Learn. Mem. 66 1996 11 23
-
(1996)
Neurobiol. Learn. Mem.
, vol.66
, pp. 11-23
-
-
Cummings, B.J.1
Head, E.2
Afagh, A.J.3
Milgram, N.W.4
Cotman, C.W.5
-
20
-
-
0029937437
-
The canine as an animal model of human aging and dementia
-
B.J. Cummings, E. Head, W. Ruehl, N.W. Milgram, and C.W. Cotman The canine as an animal model of human aging and dementia Neurobiol. Aging 17 1996 259 268
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 259-268
-
-
Cummings, B.J.1
Head, E.2
Ruehl, W.3
Milgram, N.W.4
Cotman, C.W.5
-
21
-
-
0029835167
-
Diffuse plaques contain C-terminal a beta 42 and not a beta 40: Evidence from cats and dogs
-
B.J. Cummings, T. Satou, E. Head, N.W. Milgram, G.M. Cole, M.J. Savage, M.B. Podlisny, D.J. Selkoe, R. Siman, B.D. Greenberg, and C.W. Cotman Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs Neurobiol. Aging 17 1996 653 659
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 653-659
-
-
Cummings, B.J.1
Satou, T.2
Head, E.3
Milgram, N.W.4
Cole, G.M.5
Savage, M.J.6
Podlisny, M.B.7
Selkoe, D.J.8
Siman, R.9
Greenberg, B.D.10
Cotman, C.W.11
-
22
-
-
0015965912
-
Human memory and the cholinergic system. A relationship to aging?
-
D.A. Drachman, and J. Leavitt Human memory and the cholinergic system. A relationship to aging? Arch. Neurol. 30 1974 113 121
-
(1974)
Arch. Neurol.
, vol.30
, pp. 113-121
-
-
Drachman, D.A.1
Leavitt, J.2
-
23
-
-
0022965809
-
Behavioral effects of deprenyl in aged rats
-
F. Drago, G. Continella, F. Spadaro, S. Cavaliere, and U. Scapagnini Behavioral effects of deprenyl in aged rats Funct. Neurology 2 1986 165 174
-
(1986)
Funct. Neurology
, vol.2
, pp. 165-174
-
-
Drago, F.1
Continella, G.2
Spadaro, F.3
Cavaliere, S.4
Scapagnini, U.5
-
25
-
-
0025949464
-
Mild cognitive impairment in the elderly: Predictors of dementia
-
C. Flicker, S.H. Ferris, and B. Reisberg Mild cognitive impairment in the elderly: predictors of dementia Neurology 41 1991 1006 1009
-
(1991)
Neurology
, vol.41
, pp. 1006-1009
-
-
Flicker, C.1
Ferris, S.H.2
Reisberg, B.3
-
26
-
-
0033014981
-
The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age
-
M.I. Fonseca, E. Head, P. Velazquez, C.W. Cotman, and A.J. Tenner The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age Exp. Neurol. 157 1999 277 288
-
(1999)
Exp. Neurol.
, vol.157
, pp. 277-288
-
-
Fonseca, M.I.1
Head, E.2
Velazquez, P.3
Cotman, C.W.4
Tenner, A.J.5
-
27
-
-
0024730156
-
Spatial and visual learning deficits in Alzheimer's and Parkinson's disease
-
M. Freedman, and M. Oscar-Berman Spatial and visual learning deficits in Alzheimer's and Parkinson's disease Brain Cogn. 11 1989 114 126
-
(1989)
Brain Cogn.
, vol.11
, pp. 114-126
-
-
Freedman, M.1
Oscar-Berman, M.2
-
28
-
-
0027977702
-
Chronic l-deprenyl or l-amphetamine: Equal cognitive enhancement, unequal MAO inhibition
-
D.L. Gelowitz, J.S. Richardson, T.B. Wishart, P.H. Yu, and C. Lai Chronic l-deprenyl or l-amphetamine: equal cognitive enhancement, unequal MAO inhibition Pharmacol. Biochem. Behav. 47 1994 41 45
-
(1994)
Pharmacol. Biochem. Behav.
, vol.47
, pp. 41-45
-
-
Gelowitz, D.L.1
Richardson, J.S.2
Wishart, T.B.3
Yu, P.H.4
Lai, C.5
-
29
-
-
0032053403
-
Facilitative effects of the ampakine CX-516 on short-term memory in rats: Enhancement of delayed-nonmatch-to-sample performance
-
R.E. Hampson, G. Rogers, G. Lynch, and S.A. Deadwyler Facilitative effects of the ampakine CX-516 on short-term memory in rats: enhancement of delayed-nonmatch-to-sample performance J. Neurosci. 18 7 1998 2740 2747
-
(1998)
J. Neurosci.
, vol.18
, Issue.7
, pp. 2740-2747
-
-
Hampson, R.E.1
Rogers, G.2
Lynch, G.3
Deadwyler, S.A.4
-
30
-
-
0032053963
-
Facilitative effects of the ampakine CX-516 on short-term memory in rats: Correlations with hippocampal neuronal activity
-
R.E. Hampson, G. Rogers, G. Lynch, and S.A. Deadwyler Facilitative effects of the ampakine CX-516 on short-term memory in rats: correlations with hippocampal neuronal activity J. Neurosci. 18 7 1998 2748 2763
-
(1998)
J. Neurosci.
, vol.18
, Issue.7
, pp. 2748-2763
-
-
Hampson, R.E.1
Rogers, G.2
Lynch, G.3
Deadwyler, S.A.4
-
31
-
-
15744375527
-
Brain aging in the dog: Parallels with human brain aging and Alzheimer's disease
-
E. Head Brain aging in the dog: parallels with human brain aging and Alzheimer's disease Vet. Ther. 2 2001 247 260
-
(2001)
Vet. Ther.
, vol.2
, pp. 247-260
-
-
Head, E.1
-
32
-
-
0026480922
-
Changes in spontaneous behavior in the dog following oral administration of l-deprenyl
-
E. Head, and N.W. Milgram Changes in spontaneous behavior in the dog following oral administration of l-deprenyl Pharmacol. Biochem. Behav. 43 1992 749 757
-
(1992)
Pharmacol. Biochem. Behav.
, vol.43
, pp. 749-757
-
-
Head, E.1
Milgram, N.W.2
-
33
-
-
0036008556
-
Insights into Abeta and presenilin from a canine model of human brain aging
-
E. Head, and R. Torp Insights into Abeta and presenilin from a canine model of human brain aging Neurobiol. Dis. 9 2002 1 10
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 1-10
-
-
Head, E.1
Torp, R.2
-
34
-
-
0028784660
-
Spatial learning and memory as a function of age in the dog
-
E. Head, R. Mehta, J. Hartley, M. Kameka, B.J. Cummings, C.W. Cotman, W.W. Ruehl, and N.W. Milgram Spatial learning and memory as a function of age in the dog Behav. Neurosci. 109 1995 851 858
-
(1995)
Behav. Neurosci.
, vol.109
, pp. 851-858
-
-
Head, E.1
Mehta, R.2
Hartley, J.3
Kameka, M.4
Cummings, B.J.5
Cotman, C.W.6
Ruehl, W.W.7
Milgram, N.W.8
-
35
-
-
0029665079
-
The effects of l-deprenyl on spatial short-term memory in young and aged dogs
-
E. Head, J. Hartley, A.M. Kameka, R. Mehta, G.O. Ivy, W.W. Ruehl, and N.W. Milgram The effects of l-deprenyl on spatial short-term memory in young and aged dogs Prog. Neuro-Psychopharmacol. Biol. Psychiatry 20 3 1996 515 530
-
(1996)
Prog. Neuro-Psychopharmacol. Biol. Psychiatry
, vol.20
, Issue.3
, pp. 515-530
-
-
Head, E.1
Hartley, J.2
Kameka, A.M.3
Mehta, R.4
Ivy, G.O.5
Ruehl, W.W.6
Milgram, N.W.7
-
36
-
-
0032410562
-
Visual-discrimination learning ability and beta-amyloid accumulation in the dog
-
E. Head, H. Callahan, B.A. Muggenburg, C.W. Cotman, and N.W. Milgram Visual-discrimination learning ability and beta-amyloid accumulation in the dog Neurobiol. Aging 19 1998 415 425
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 415-425
-
-
Head, E.1
Callahan, H.2
Muggenburg, B.A.3
Cotman, C.W.4
Milgram, N.W.5
-
37
-
-
0034594462
-
Region-specific age at onset of beta-amyloid in dogs
-
E. Head, R. McCleary, F.F. Hahn, N.W. Milgram, and C.W. Cotman Region-specific age at onset of beta-amyloid in dogs Neurobiol. Aging 21 2000 89 96
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 89-96
-
-
Head, E.1
McCleary, R.2
Hahn, F.F.3
Milgram, N.W.4
Cotman, C.W.5
-
38
-
-
0036069450
-
Oxidative damage increases with age in a canine model of human brain aging
-
E. Head, J. Liu, T.M. Hagen, B.A. Muggenburg, N.W. Milgram, B.N. Ames, and C.W. Cotman Oxidative damage increases with age in a canine model of human brain aging J. Neurochem. 82 2002 375 381
-
(2002)
J. Neurochem.
, vol.82
, pp. 375-381
-
-
Head, E.1
Liu, J.2
Hagen, T.M.3
Muggenburg, B.A.4
Milgram, N.W.5
Ames, B.N.6
Cotman, C.W.7
-
39
-
-
0028894038
-
Maze learning in aged rats is enhanced by phenserine, a novel anticholinesterase
-
H. Ikari, E.L. Spangler, N.H. Greig, X.F. Pei, A. Brossi, D. Speer, N. Patel, and D.K. Ingram Maze learning in aged rats is enhanced by phenserine, a novel anticholinesterase NeuroReport 6 1995 481 484
-
(1995)
NeuroReport
, vol.6
, pp. 481-484
-
-
Ikari, H.1
Spangler, E.L.2
Greig, N.H.3
Pei, X.F.4
Brossi, A.5
Speer, D.6
Patel, N.7
Ingram, D.K.8
-
40
-
-
0036672725
-
Randomized, double-blind, placebo-controlled international clinical trial of the Ampakine CX516 in elderly participants with mild cognitive impairment: A progress report
-
S.A. Johnson, and V.F. Simmon Randomized, double-blind, placebo-controlled international clinical trial of the Ampakine CX516 in elderly participants with mild cognitive impairment: a progress report J. Mol. Neurosci. 1999 197 200
-
(1999)
J. Mol. Neurosci.
, pp. 197-200
-
-
Johnson, S.A.1
Simmon, V.F.2
-
41
-
-
0025853543
-
Conservation of the sequence of Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis
-
E.M. Johnstone, M.O. Chaney, F.H. Norris, R. Pascual, and S.P. Little Conservation of the sequence of Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis Mol. Brain Res. 10 1991 299 305
-
(1991)
Mol. Brain Res.
, vol.10
, pp. 299-305
-
-
Johnstone, E.M.1
Chaney, M.O.2
Norris, F.H.3
Pascual, R.4
Little, S.P.5
-
42
-
-
84996074735
-
The pharmacology of selegiline ((-)deprenyl). New aspects
-
J. Knoll The pharmacology of selegiline ((-)deprenyl). New aspects Acta Neurol. Scand. 126 1989 83 91
-
(1989)
Acta Neurol. Scand.
, vol.126
, pp. 83-91
-
-
Knoll, J.1
-
43
-
-
85030808472
-
-
Lundbeck Institute, 2003. Icopezil maleate. http://www.psychotropics.dk/ usr_view_molecule.asp?ID=2265&backurl= Codeindex%2Fview%5FCodes%2Easp%3FStartchar%3DC&backurlname= Code+numbers&historyline=&Catalogtype=A.
-
(2003)
Icopezil Maleate
-
-
-
44
-
-
0142021005
-
Cognitive experience and its effect on age-dependent cognitive decline in beagle dogs
-
N.W. Milgram Cognitive experience and its effect on age-dependent cognitive decline in beagle dogs Neurochem. Res. 28 2003 1677 1682
-
(2003)
Neurochem. Res.
, vol.28
, pp. 1677-1682
-
-
Milgram, N.W.1
-
45
-
-
0028331373
-
Cognitive functions and aging in the dog: Acquisition of nonspatial visual tasks
-
N.W. Milgram, E. Head, E. Weiner, and E. Thomas Cognitive functions and aging in the dog: acquisition of nonspatial visual tasks Behav. Neurosci. 108 1994 57 68
-
(1994)
Behav. Neurosci.
, vol.108
, pp. 57-68
-
-
Milgram, N.W.1
Head, E.2
Weiner, E.3
Thomas, E.4
-
46
-
-
0029037575
-
Effects of chronic oral administration of l-deprenyl in the dog
-
N.W. Milgram, G.O. Ivy, E. Head, M.P. Murphy, P.H. Wu, W.W. Ruehl, P.H. Yu, D.A. Durden, B.A. Davis, and A.A. Boulton Effects of chronic oral administration of l-deprenyl in the dog Pharmacol. Biochem. Behav. 51 1995 421 428
-
(1995)
Pharmacol. Biochem. Behav.
, vol.51
, pp. 421-428
-
-
Milgram, N.W.1
Ivy, G.O.2
Head, E.3
Murphy, M.P.4
Wu, P.H.5
Ruehl, W.W.6
Yu, P.H.7
Durden, D.A.8
Davis, B.A.9
Boulton, A.A.10
-
47
-
-
0032955087
-
Landmark discrimination learning in the dog
-
N.W. Milgram, B. Adams, H. Callahan, E. Head, B. Mackay, C. Thirlwell, and C.W. Cotman Landmark discrimination learning in the dog Learn. Memory 6 1999 54 61
-
(1999)
Learn. Memory
, vol.6
, pp. 54-61
-
-
Milgram, N.W.1
Adams, B.2
Callahan, H.3
Head, E.4
MacKay, B.5
Thirlwell, C.6
Cotman, C.W.7
-
48
-
-
0034092374
-
Oral administration of adrafinil improves discrimination learning in aged beagle dogs
-
N.W. Milgram, C.T. Siwak, P. Gruet, P. Atkinson, F. Woehrle, and H. Callahan Oral administration of adrafinil improves discrimination learning in aged beagle dogs Pharmacol. Biochem. Behav. 66 2 2000 301 305
-
(2000)
Pharmacol. Biochem. Behav.
, vol.66
, Issue.2
, pp. 301-305
-
-
Milgram, N.W.1
Siwak, C.T.2
Gruet, P.3
Atkinson, P.4
Woehrle, F.5
Callahan, H.6
-
49
-
-
0036819096
-
Landmark discrimination learning in the dog: Effects of age, an antioxidant fortified food, and cognitive strategy
-
N.W. Milgram, E. Head, B. Muggenburg, D. Holowachuk, H. Murphey, J. Estrada, C.J. Ikeda-Douglas, S.C. Zicker, and C.W. Cotman Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy Neurosci. Biobehav. Rev. 26 2002 679 695
-
(2002)
Neurosci. Biobehav. Rev.
, vol.26
, pp. 679-695
-
-
Milgram, N.W.1
Head, E.2
Muggenburg, B.3
Holowachuk, D.4
Murphey, H.5
Estrada, J.6
Ikeda-Douglas, C.J.7
Zicker, S.C.8
Cotman, C.W.9
-
50
-
-
0036752043
-
Dietary enrichment counteracts age-associated cognitive dysfunction in canines
-
N.W. Milgram, S.C. Zicker, E. Head, B.A. Muggenburg, H. Murphey, C.J. Ikeda-Douglas, and C.W. Cotman Dietary enrichment counteracts age-associated cognitive dysfunction in canines Neurobiol. Aging 23 5 2002 737 745
-
(2002)
Neurobiol. Aging
, vol.23
, Issue.5
, pp. 737-745
-
-
Milgram, N.W.1
Zicker, S.C.2
Head, E.3
Muggenburg, B.A.4
Murphey, H.5
Ikeda-Douglas, C.J.6
Cotman, C.W.7
-
51
-
-
0023973421
-
Primary and working memory functioning in Alzheimer-type dementia
-
R.G. Morris, and A.D. Baddeley Primary and working memory functioning in Alzheimer-type dementia J. Clin. Exp. Neuropsychol. 10 1988 279 296
-
(1988)
J. Clin. Exp. Neuropsychol.
, vol.10
, pp. 279-296
-
-
Morris, R.G.1
Baddeley, A.D.2
-
52
-
-
0035675776
-
Investigating potential anxiolytic, antidepressant and memory enhancing activity of deprenyl
-
E. Nowakowska, K. Kus, A. Chodera, and J. Rybakowski Investigating potential anxiolytic, antidepressant and memory enhancing activity of deprenyl J. Physiol. Pharmacol. 52 2001 t-73
-
(2001)
J. Physiol. Pharmacol.
, vol.52
, pp. 73
-
-
Nowakowska, E.1
Kus, K.2
Chodera, A.3
Rybakowski, J.4
-
53
-
-
85030814485
-
Cortex's ampakine CX516 fizzles, but more potent ones in pipeline
-
Osborne, R., 2004. Cortex's ampakine CX516 fizzles, but more potent ones in pipeline. Bioworld Online. http://www.bioworld.com/servlet/com.accumedia.web. Dispatcher?next=bioWorldHeadlines_article&forceid=32153.
-
(2004)
Bioworld Online
-
-
Osborne, R.1
-
54
-
-
0032484682
-
Phenserine, a novel acetylcholinesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockade of the N-methyl-d-aspartate receptor
-
N. Patel, E.L. Spangler, N.H. Greig, Q.S. Yu, D.K. Ingram, and R.C. Meyer Phenserine, a novel acetylcholinesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockade of the N-methyl-d-aspartate receptor NeuroReport 9 1998 171 176
-
(1998)
NeuroReport
, vol.9
, pp. 171-176
-
-
Patel, N.1
Spangler, E.L.2
Greig, N.H.3
Yu, Q.S.4
Ingram, D.K.5
Meyer, R.C.6
-
55
-
-
0037452854
-
Glutamate receptor function in learning and memory
-
G. Riedel, B. Platt, and J. Micheau Glutamate receptor function in learning and memory Behav. Brain Res. 140 2003 1 47
-
(2003)
Behav. Brain Res.
, vol.140
, pp. 1-47
-
-
Riedel, G.1
Platt, B.2
Micheau, J.3
-
58
-
-
0029564645
-
Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: Clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy
-
W.W. Ruehl, D.S. Bruyette, A. DePaoli, C.W. Cotman, E. Head, N.W. Milgram, and B.J. Cummings Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy Prog. Brain Res. 106 1995 217 225
-
(1995)
Prog. Brain Res.
, vol.106
, pp. 217-225
-
-
Ruehl, W.W.1
Bruyette, D.S.2
Depaoli, A.3
Cotman, C.W.4
Head, E.5
Milgram, N.W.6
Cummings, B.J.7
-
59
-
-
0031558637
-
The progression of beta-amyloid deposition in the frontal cortex of the aged canine
-
T. Satou, B.J. Cummings, E. Head, K.A. Nielson, F.F. Hahn, N.W. Milgram, P. Velazquez, D.H. Cribbs, A.J. Tenner, and C.W. Cotman The progression of beta-amyloid deposition in the frontal cortex of the aged canine Brain Res. 774 1997 35 43
-
(1997)
Brain Res.
, vol.774
, pp. 35-43
-
-
Satou, T.1
Cummings, B.J.2
Head, E.3
Nielson, K.A.4
Hahn, F.F.5
Milgram, N.W.6
Velazquez, P.7
Cribbs, D.H.8
Tenner, A.J.9
Cotman, C.W.10
-
60
-
-
0023118252
-
Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease
-
D.J. Selkoe, D.S. Bell, M.B. Podlisny, D.L. Price, and L.C. Cork Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease Science 235 1987 873 877
-
(1987)
Science
, vol.235
, pp. 873-877
-
-
Selkoe, D.J.1
Bell, D.S.2
Podlisny, M.B.3
Price, D.L.4
Cork, L.C.5
-
62
-
-
0034098359
-
Behavioral activating effects of adrafinil in aged canines
-
C.T. Siwak, P. Gruet, F. Woehrle, M. Schneider, B.A. Muggenberg, H.L. Murphey, H. Callahan, and N.W. Milgram Behavioral activating effects of adrafinil in aged canines Pharmacol. Biochem. Behav. 66 2000 293 300
-
(2000)
Pharmacol. Biochem. Behav.
, vol.66
, pp. 293-300
-
-
Siwak, C.T.1
Gruet, P.2
Woehrle, F.3
Schneider, M.4
Muggenberg, B.A.5
Murphey, H.L.6
Callahan, H.7
Milgram, N.W.8
-
63
-
-
1642352859
-
Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogs
-
C.T. Siwak, P.D. Tapp, and N.W. Milgram Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogs Pharmacol. Biochem. Behav. 76 1 2003 161 168
-
(2003)
Pharmacol. Biochem. Behav.
, vol.76
, Issue.1
, pp. 161-168
-
-
Siwak, C.T.1
Tapp, P.D.2
Milgram, N.W.3
-
64
-
-
0032440880
-
Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging
-
M.Y. Su, E. Head, W.M. Brooks, Z. Wang, B.A. Muggenburg, G.E. Adam, R. Sutherland, C.W. Cotman, and O. Nalcioglu Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging Neurobiol. Aging 19 1998 479 485
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 479-485
-
-
Su, M.Y.1
Head, E.2
Brooks, W.M.3
Wang, Z.4
Muggenburg, B.A.5
Adam, G.E.6
Sutherland, R.7
Cotman, C.W.8
Nalcioglu, O.9
-
65
-
-
0013015637
-
Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging
-
P.D. Tapp, C.T. Siwak, J. Estrada, E. Head, B.A. Muggenburg, C.W. Cotman, and N.W. Milgram Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging Learn. Memory 10 2003 64 73
-
(2003)
Learn. Memory
, vol.10
, pp. 64-73
-
-
Tapp, P.D.1
Siwak, C.T.2
Estrada, J.3
Head, E.4
Muggenburg, B.A.5
Cotman, C.W.6
Milgram, N.W.7
-
66
-
-
12444298979
-
Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigm
-
P.D. Tapp, C.T. Siwak, J. Estrada, D. Holowachuk, and N.W. Milgram Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigm Learn. Memory 10 2003 148 160
-
(2003)
Learn. Memory
, vol.10
, pp. 148-160
-
-
Tapp, P.D.1
Siwak, C.T.2
Estrada, J.3
Holowachuk, D.4
Milgram, N.W.5
-
67
-
-
0033888962
-
Ultrastructural analyses of beta-amyloid in the aged dog brain: Neuronal beta-amyloid is localized to the plasma membrane
-
R. Torp, E. Head, and C.W. Cotman Ultrastructural analyses of beta-amyloid in the aged dog brain: neuronal beta-amyloid is localized to the plasma membrane Prog. Neuro-Psychopharmacol. Biol. Psychiatry 24 2000 801 810
-
(2000)
Prog. Neuro-Psychopharmacol. Biol. Psychiatry
, vol.24
, pp. 801-810
-
-
Torp, R.1
Head, E.2
Cotman, C.W.3
-
68
-
-
0034008482
-
Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains
-
R. Torp, E. Head, N.W. Milgram, F. Hahn, O.P. Ottersen, and C.W. Cotman Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains Neuroscience 96 2000 495 506
-
(2000)
Neuroscience
, vol.96
, pp. 495-506
-
-
Torp, R.1
Head, E.2
Milgram, N.W.3
Hahn, F.4
Ottersen, O.P.5
Cotman, C.W.6
-
69
-
-
20444434415
-
-
Tufts Center for the Study of Drug Development, 2004. Outlook 2004. http://csdd.tufts.edu/InfoServices/OutlookPDFs/Outlook2004.pdf.
-
(2004)
Outlook 2004
-
-
-
70
-
-
0036163534
-
The effect of selegiline in the treatment of people with Alzheimer's disease: A meta-analysis of published trials
-
G.K. Wilcock, J. Birks, A. Whitehead, and S.J. Evans The effect of selegiline in the treatment of people with Alzheimer's disease: a meta-analysis of published trials Int. J. Geriatr. Psychiatry 17 2002 175 183
-
(2002)
Int. J. Geriatr. Psychiatry
, vol.17
, pp. 175-183
-
-
Wilcock, G.K.1
Birks, J.2
Whitehead, A.3
Evans, S.J.4
-
71
-
-
0032191831
-
Changes in NMDA receptor/nitric oxide signaling pathway in the brain with aging
-
K. Yamada, and T. Nabeshima Changes in NMDA receptor/nitric oxide signaling pathway in the brain with aging Microsc. Res. Tech. 43 1998 68 74
-
(1998)
Microsc. Res. Tech.
, vol.43
, pp. 68-74
-
-
Yamada, K.1
Nabeshima, T.2
-
72
-
-
34347168142
-
The interaction of l-deprenyl and scopolamine on spatial learning/memory in rats
-
L. Yavich, J. Sirvio, E. Heinonen, and S.P. Riekkinen The interaction of l-deprenyl and scopolamine on spatial learning/memory in rats J. Neural Transm. 6 1993 189 197
-
(1993)
J. Neural Transm.
, vol.6
, pp. 189-197
-
-
Yavich, L.1
Sirvio, J.2
Heinonen, E.3
Riekkinen, S.P.4
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