Ultrastructural analyses of β-amyloid in the aged dog brain: Neuronal β-amyloid is localized to the plasma membrane

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 24, Issue 5, 2000, Pages 801-810

  Torp, Reidun ^a   Head, Elizabeth ^b   Cotman, Carl W ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Electron microscopy; Immunocytochemistry; Neuropathology; Amyloid

Indexed keywords

AMYLOID BETA PROTEIN;

AGING; ANIMAL TISSUE; BRAIN; CORRELATION FUNCTION; DOG; ELECTRON MICROSCOPY; IMMUNOCYTOCHEMISTRY; NEUROPATHOLOGY; NONHUMAN; PROTEIN LOCALIZATION; REVIEW; TISSUE DISTRIBUTION; ULTRASTRUCTURE;

EID: 0033888962     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(00)00107-X     Document Type: Article

References (16)

1. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine
2. Beta-amyloid accumulation in aged canine brain: A model of plaque formation in Alzheimer's disease
3. Distinct sites of intracellular production for Alzheimer's disease. Abeta 40/42 amyloid peptides
4. Discrimination learning ability and beta amyloid accumulation in the dog
5. Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay
6. Organization of AMPA receptor subunits at a glutamate synapse: A quantitative immunogold analysis of hair cell synapses in the rat organ of Corti
7. Amyloid deposits and loss of neurones in the claustrum of the aged dog
8. Metabolic compartmentalization of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
9. Age-specific onset of beta-amyloid in beagle brains
10. Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components
11. MR Imaging of anatomic and vascular characteristics in a canine model of human aging
12. Different modes of expression of AMPA and NMDA receptors in hippocampal synapses
13. Freeze-substitution and Lowicryl HM20 embedding of fixed rat brain: Suitability for immunogold ultrastructural localization of neuronal antigens
14. Simultaneous demonstration of multiple antigens by indirect immunofluorescence or immunogold staining
15. The origin of amyloid in cerebral vessels of aged dogs