Secretion and absorption by colonic crypts

Annual Review of Physiology

Volumn 67, Issue , 2005, Pages 471-490

  Geibel, John P ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chloride; Colon; Electrolyte transport; Fluid; Sodium

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL TOXIN; BICARBONATE; CALCIUM ION; CALCIUM SENSING RECEPTOR; CHLORIDE; CHLORIDE CHANNEL; CHOLERA TOXIN; CYCLIC AMP; CYCLIC GMP; GADOLINIUM; NEOMYCIN; POTASSIUM CHANNEL; SODIUM; SODIUM CHLORIDE;

ANIMAL CELL; BASOLATERAL MEMBRANE; CELL TYPE; COLON MUCOSA; CROHN DISEASE; DIARRHEA; ELECTROLYTE TRANSPORT; FLUID TRANSPORT; INTESTINE CRYPT; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; COLON; HUMANS; INTESTINAL ABSORPTION; MICROVILLI;

EID: 15544382862     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.67.031103.153530     Document Type: Review

References (103)

1. Bakre MM, Ghanekar Y, Visweswariah SS. 2000. Homologous desensitization of the human guanylate cyclase C receptor. Cell-specific regulation of catalytic activity. Eur. J. Biochem. 267:179-87
2. Bakre MM, Sopory S, Visweswariah SS. 2000. Expression and regulation of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) in human colonic epithelial cells: role in the induction of cellular refractoriness to the heat-stable enterotoxin peptide. J. Cell Biochem. 77:159-67
3. Deleted in proof
4. Bakre MM, Visweswariah SS. 1997. Dual regulation of heat-stable enterotoxin-mediated cGMP accumulation in T84 cells by receptor desensitization and increased phosphodiesterase activity. FEBS Lett. 408:345-49
5. Barrett KE, Keely SJ. 2000. Chloride secretion by the intestinal epithelium: molecular basis and regulatory aspects. Annu. Rev. Physiol. 62:535-72
6. Benos DJ, Cunningham S, Baker RR, Beason KB, Oh Y, Smith PR. 1992. Molecular characteristics of amiloride-sensitive sodium channels. Rev. Physiol. Biochem. Pharmacol. 120:31-113
7. Binder HJ, Foster ES, Budinger ME, Hayslett JP. 1987. Mechanism of electroneutral sodium chloride absorption in distal colon of the rat. Gastroenterology 93:449-55
8. + transport. J. Physiol. 410:425-41
9. Binder HJ, Rajendran VM, Geibel JP. 2000. Cl-dependent Na-H exchange. A novel colonic crypt transport mechanism. Ann. NY Acad. Sci. 915:43-53
10. Binder HJ, Singh SK, Geibel JP, Rajendran VM. 1997. Novel transport properties of colonic crypt cells: fluid absorption and Cl-dependent Na-H exchange. Comp. Biochem. Physiol. A 118:265-69
11. Bleich M, Ecke D, Schwartz B, Fraser G, Greger R. 1997. Effects of the carcinogen dimethylhydrazine (DMH) on the function of rat colonic crypts. Pflügers Arch. 433:254-59
12. + channels (ENaCs) in Xenopus oocytes co-expressing CFTR and ENaC. J. Physiol. 508:825-36
13. Budinger ME, Foster ES, Hayslett JP, Binder HJ. 1986. Sodium and chloride transport in the large intestine of potassium-loaded rats. Am. J. Physiol. Gastrointest. Liver Physiol. 251:G249-52
14. Butterfield I, Warhurst G, Jones MN, Sandie GI. 1997. Characterization of apical potassium channels induced in rat distal colon during potassium adaptation. J. Physiol. 501:537-47
15. Cartwright CA, Mamajiwalla S, Skolnick SA, Eckhart W, Burgess DR. 1993. Intestinal crypt cells contain higher levels of cytoskeletal-associated pp60c-src protein tyrosine kinase activity than do differentiated enterocytes. Oncogene 8:1033-39
16. Chang EB, Bergenstal RM, Field M. 1985. Diarrhea in streptozocin-treated rats. Loss of adrenergic regulation of intestinal fluid and electrolyte transport. J. Clin. Invest. 75:1666-70
17. Chang EB, Brown DR, Field M, Miller RJ. 1984. An antiabsorptive basis for precipitated withdrawal diarrhea in morphine-dependent rats. J. Pharmacol. Exp. Ther. 228:364-69
18. Chang EB, Fedorak RN, Field M. 1986. Experimental diabetic diarrhea in rats. Intestinal mucosal denervation hypersensitivity and treatment with clonidine. Gastroenterology 91:564-69
19. Cheng SX, Geibel JP, Hebert SC. 2004. Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptor. Gastroenterology 126:148-58
20. Cheng SX, Okuda M, Hall AE, Geibel JP, Hebert SC. 2002. Expression of calcium-sensing receptor in rat colonic epithelium: evidence for modulation of fluid secretion. Am. J. Physiol. Gastrointest. Liver Physiol. 283:G240-50
21. Clauss W, Schafer H, Horch I, Hornicke H. 1985. Segmental differences in electrical properties and Na-transport of rabbit caecum, proximal and distal colon in vitro. Pflügers Arch. 403:278-82
22. --secreting epithelial cells. Proc. Natl. Acad. Sci. USA 87:4956-60
23. Cuthbert AW, Hickman ME, MacVinish LJ, Evans MJ, Colledge WH, et al. 1994. Chloride secretion in response to guanylin in colonic epithelial from normal and transgenic cystic fibrosis mice. Br. J. Pharmacol. 112:31-36
24. Dawson DC. 1991. Ion channels and colonic salt transport? Annu. Rev. Physiol. 53:321-39
25. - cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells. J. Biol. Chem. 269:25677-83
26. Diener M, Rummel W, Mestres P, Lindemann B. 1989. Single chloride channels in colon mucosa and isolated colonic enterocytes of the rat. J. Membr. Biol. 108:21-30
27. - secretion but no cation inward conductance. Pflügers Arch. 431:427-34
28. Fargeas MJ, Theodorou V, More J, Wal JM, Fioramonti J, Bueno L. 1995. Boosted systemic immune and local responsiveness after intestinal inflammation in orally sensitized guinea pigs. Gastroenterology 109:53-62
29. Field M, Rao MC, Chang EB. 1989. Intestinal electrolyte transport and diarrheal disease (2) N. Engl. J. Med. 321:879-83
30. Field M, Rao MC, Chang EB. 1989. Intestinal electrolyte transport and diarrheal disease (1) N. Engl. J. Med. 321:800-6
31. Field M, Semrad CE. 1993. Toxigenic diarrheas, congenital diarrheas, and cystic fibrosis: disorders of intestinal ion transport. Annu. Rev. Physiol. 55:631-55
32. Fiocchi C. 1997. Intestinal inflammation: a complex interplay of immune and non-immune cell interactions. Am. J. Physiol. Gastrointest. Liver Physiol. 273:G769-75
33. Fiocchi C. 1998. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 115:182-205
34. Fiocchi C. 1999. From immune activation to gut tissue injury: the pieces of the puzzle are coming together. Gastroenterology 117:1238-41
35. Foster ES, Budinger ME, Hayslett JP, Binder HJ. 1986. Ion transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption. J. Clin. Invest. 77:228-35
36. Foster ES, Jones WJ, Hayslett JP, Binder HJ. 1985. Role of aldosterone and dietary potassium in potassium adaptation in the distal colon of the rat. Gastroenterology 88:41-46
37. Gabriel SE, Brigman KN, Koller BH, Boucher RC, Stutts MJ. 1994. Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model. Science 266:107-9
38. +-dependent fluid absorption in intact perfused rat colonic crypts. Gastroenterology 120:144-50
39. - secretion. Gastroenterology 118:101-7
40. Greger R. 2000. Role of CFTR in the colon. Annu. Rev. Physiol. 62:467-91
41. Greger R, Mall M, Bleich M, Ecke D, Warth R, et al. 1996. Regulation of epithelial ion channels by the cystic fibrosis transmembrane conductance regulator. J. Mol. Med. 74:527-34
42. Greger R, Schreiber R, Mall M, Wissner A, Hopf A, et al. 2001. Cystic fibrosis and CFTR. Pflügers Arch. 443(Suppl. 1):S3-S7
43. Haas M, Forbush B III. 1998. The Na-K-Cl cotransporters. J. Bioenerg. Biomembr. 30:161-72
44. Haas M, Forbush B III. 2000. The Na-K-Cl cotransporter of secretory epithelia. Annu. Rev. Physiol. 62:515-34
45. Halm DR, Halm ST. 2000. Secretagogue response of goblet cells and columnar cells in human colonic crypts. Am. J. Physiol. Cell Physiol. 278:C212-33
46. Harris J, Shields R. 1970. Absorption and secretion of water and electrolytes by the intact human colon in diffuse untreated proctocolitis. Gut 11:27-33
47. Hermiston ML, Gordon JI. 1995. Organization of the crypt-villus axis and evolution of its stem cell hierarchy during intestinal development. Am. J. Physiol. Gastrointest. Liver Physiol. 268:G813-22
48. Ho SB. 1992. Cytoskeleton and other differentiation markers in the colon. J. Cell Biochem. Suppl. 16G:119-28
49. + channels carrying Liddle's syndrome mutations. J. Biol. Chem. 274:13894-99
50. 3 exchange in basolateral membrane of rat distal colon. Am. J. Physiol. Cell Physiol. 285:C912-21
51. Ikuma M, Kashgarian M, Binder HJ, Rajendran VM. 1999. Differential regulation of NHE isoforms by sodium depletion in proximal and distal segments of rat colon. Am. J. Physiol. Gastrointest. Liver Physiol. 276:G539-49
52. Izzo AA, Mascolo N, Capasso F. 1998. Nitric oxide as a modulator of intestinal water and electrolyte transport. Dig. Dis. Sci. 43:1605-20
53. Jaffe LF, Nuccitelli R. 1974. An ultra-sensitive vibrating probe for measuring steady extracellular currents. J. Cell Biol. 63:614-28
54. Jarchau T, Hausler C, Marken T, Pohler D, Vanderkerckhove J, et al. 1994. Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II. Proc. Natl. Acad. Sci. USA 91:9426-30
55. - secretion from both crypts and surface epithelia of rat intestine. Am. J. Physiol. Cell Physiol. 264:C1294-301
56. + absorption of rat distal colon is confined to surface epithelium: a voltage-scanning study. Am. J. Physiol. Cell Physiol. 264:C1285-93
57. Konig J, Schreiber R, Mall M, Kunzelmann K. 2002. No evidence for inhibition of ENaC through CFTR-mediated release of ATP. Biochim. Biophys. Acta 1565:17-28
58. - channels. Pflügers Arch. 445:504-12
59. + channel. Kidney Blood Press. Res. 20:151-53
60. - channels in HT29 colon carcinoma cells. Pflügers Arch. 421:230-37
61. + currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator. FEBS Lett. 400:341-44
62. Kunzelmann K, Koslowsky T, Hug T, Gruenert DC, Greger R. 1994. cAMP-dependent activation of ion conductances in bronchial epithelial cells. Pflügers Arch. 428:590-96
63. 2+, hypotonic cell swelling and 8-Br-cGMP. Pflügers Arch. 421:238-46
64. Kunzelmann K, Mall M. 2002. Electrolyte transport in the mammalian colon: mechanisms and implications for disease. Physiol. Rev. 82:245-89
65. Levitan R, Fordtran JS, Burrows BA, Ingelfinger FJ. 1962. Water and salt absorption in the human colon. J. Clin. Invest. 41:1754-59
66. Li M, McCann JD, Liedtke CM, Nairn AC, Greengard P, Welsh MJ. 1988. Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium. Nature 331:358-60
67. Lipsky MS, Adelman M. 1993. Chronic diarrhea: evaluation and treatment. Am. Fam. Physician 48:1461-66
68. + conductance. Pflügers Arch. 429:517-30
69. - secretion by forskolin. Pflügers Arch. 425:373-80
70. Lohrmann E, Greger R. 1995. The effect of secretagogues on ion conductances of in vitro perfused, isolated rabbit colonic crypts. Pflügers Arch. 429:494-502
71. + channels in the basolateral membrane of crypt cells isolated from rabbit distal colon. J. Membr. Biol. 110:19-28
72. Lytle C, Forbush B III. 1996. Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: modulation by cytoplasmic Cl. Am. J. Physiol. Cell Physiol. 270:C437-48
73. + conductance in human colon is defective in cystic fibrosis. Am. J. Physiol. Gastrointest. Liver Physiol. 277:G709-16
74. Mall M, Bleich M, Schurlein M, Kuhr J, Seydewitz HH, et al. 1998. Cholinergic ion secretion in human colon requires coactivation by cAMP. Am. J. Physiol. Gastrointest. Liver Physiol. 275:G1274-81
75. Mall M, Kreda SM, Mengos A, Jensen TJ, Hirtz S, et al. 2004. The DeltaF508 mutation results in loss of CFTR function and mature protein in native human colon. Gastroenterology 126:32-41
76. + exchanger. J. Biol. Chem. 274:22855-61
77. Naftalin RJ, Pedley KC. 1999. Regional crypt function in rat large intestine in relation to fluid absorption and growth of the pericryptal sheath. J. Physiol. 514:211-27
78. Naftalin RJ, Zammit PS, Pedley KC. 1999. Regional differences in rat large intestinal crypt function in relation to dehydrating capacity in vivo. J. Physiol. 514:201-10
79. Payne JA, Xu JC, Haas M, Lytle CY, Ward D, Forbush B III. 1995. Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon. J. Biol. Chem. 270:17977-85
80. Pedley KC, Naftalin RJ. 1993. Evidence from fluorescence microscopy and comparative studies that rat, ovine and bovine colonic crypts are absorptive. J. Physiol. 460:525-47
81. Quist RG, Ton-Nu HT, Lillienau J, Hofmann AF, Barrett KE. 1991. Activation of mast cells by bile acids. Gastroenterology 101:446-56
82. Rajendran VM, Binder HJ. 2000. Characterization and molecular localization of anion transporters in colonic epithelial cells. Ann. NY Acad. Sci. 915:15-29
83. Rajendran VM, Black J, Ardito TA, Sangan P, Alper SL, et al. 2000. Regulation of DRA and AE1 in rat colon by dietary Na depletion. Am. J. Physiol. Gastrointest. Liver Physiol. 279:G931-42
84. Rajendran VM, Geibel J, Binder HJ. 1999. Role of Cl channels in Cl-dependent Na/H exchange. Am. J. Physiol. Gastrointest. Liver Physiol. 276:G73-78
85. Rajendran VM, Kashgarian M, Binder HJ. 1989. Aldosterone induction of electrogenic sodium transport in the apical membrane vesicles of rat distal colon. J. Biol. Chem. 264:18638-44
86. Rao MC, Field M. 1984. Enterotoxins and ion transport. Biochem. Soc. Trans. 12:177-80
87. Rao MC, Guandalini S, Laird WJ, Field M. 1979. Effects of heat-stable enterotoxin of Yersinia enterocolitica on ion transport and cyclic guanosine 3′,5′-monophosphate metabolism in rabbit ileum. Infect. Immun. 26:875-78
88. Rao MC, Guandalini S, Smith PL, Field M. 1980. Mode of action of heat-stable Escherichia coli enterotoxin. Tissue and subcellular specificities and role of cyclic GMP. Biochim. Biophys. Acta 632:35-46
89. Rao MC, Nash NT, Field M. 1984. Differing effects of cGMP and cAMP on ion transport across flounder intestine. Am. J. Physiol. Cell Physiol. 246:C167-71
90. Rao MC, Orellana SA, Field M, Robertson DC, Giannella RA. 1981. Comparison of the biological actions of three purified heat-stable enterotoxins: effects on ion transport and guanylate cyclase activity in rabbit ileum in vitro. Infect. Immun. 33:165-70
91. Rijke RP, Plaisier HM, Langendoen NJ. 1979. Epithelial cell kinetics in the descending colon of the rat. Virchows Arch. B 30:85-94
92. Robert ME, Singh SK, Ikuma M, Jain D, Ardito T, Binder HJ. 2001. Morphology of isolated colonic crypts. Cells Tissues Organs 168:246-51
93. Sandle GI, Foster ES, Lewis SA, Binder HJ, Hayslett JP. 1985. The electrical basis for enhanced potassium secretion in rat distal colon during dietary potassium loading. Pflügers Arch. 403:433-39
94. Sandle GI, Hayslett JP, Binder HJ. 1984. Effect of chronic hyperaldosteronism on the electrophysiology of rat distal colon. Pflügers Arch. 401:22-26
95. Saxon ML, Zhao X, Black JD. 1994. Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ. J. Cell Biol. 126:747-63
96. Singh SK, Binder HJ, Boron WF, Geibel JP. 1995. Fluid absorption in isolated perfused colonic crypts. J. Clin. Invest. 96:2373-79
97. + channels. Annu. Rev. Physiol. 53:509-30
98. + channels and colonic function. Rev. Physiol. Biochem. Pharmacol. 140:1-62
99. Weinman EJ, Steplock D, Donowitz M, Shenolikar S. 2000. NHERF associations with sodium-hydrogen exchanger isoform 3 (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3. Biochemistry 39:6123-29
100. Welsh MJ, Smith PL, Fromm M, Frizzell RA. 1982. Crypts are the site of intestinal fluid and electrolyte secretion. Science 218:1219-21
101. Deleted in proof
102. Worrell RT, Butt AG, Cliff WH, Frizzell RA. 1989. A volume-sensitive chloride conductance in human colonic cell line. T84. Am. J. Physiol. Cell Physiol. 256: C11110-19
103. + exchanger, NHE3, requires an associated regulatory protein. Proc. Natl. Acad. Sci. USA 94:3010-15