Downregulation of AQP1, -2, and -3 after ureteral obstruction is associated with a long-term urine-concentrating defect

American Journal of Physiology - Renal Physiology

Volumn 281, Issue 1 50-1, 2001, Pages

  Li, Chunling ^a,b   Wang, Weidong ^a   Kwon, Tae Hwan ^a   Isikay, Levent ^a   Wen, Jian Guo ^a   Marples, David ^c   Djurhuus, Jens Christian ^a   Stockwell, Anette ^a   Knepper, Mark A ^d   Nielsen, Søren ^a   Frøkiær, Jørgen ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d Laboratory of Kidney and Electrolyte Metabolism NHBLI   (United States)

Author keywords

Aquaporin 1; Aquaporin 2; Aquaporin 3; Collecting duct; Nephrogenic diabetes insipidus; Obstructive nephropathy; Polyuria; Proximal tubule

Indexed keywords

AQUAPORIN 1; AQUAPORIN 2; AQUAPORIN 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HENLE LOOP; IMMUNOBLOTTING; KIDNEY CLEARANCE; KIDNEY COLLECTING TUBULE; KIDNEY CONCENTRATING CAPACITY; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; MALE; NEPHROGENIC DIABETES INSIPIDUS; NONHUMAN; POLYURIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; URETER OBSTRUCTION; URINE VOLUME;

EID: 15444365819     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.281.1.f163     Document Type: Article

References (43)

1. Concentration of urine in the mammalian kidney
2. Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice
3. Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice
4. Urinary tract obstruction
5. Glomerular hemodynamics before and after release of 24-h bilateral ureteral obstruction
6. Decreased aquaporin-2 expression and apical plasma membrane delivery in kidney collecting ducts of polyuric hypercalcemic rats
7. Aquaporin-3 water channel localization and regulation in rat kidney
8. Downregulation of aquaporin-2 parallels changes in renal water excretion in unilateral ureteral obstruction
9. Enhanced intrarenal angiotensin II generation in response to obstruction of the pig ureter
10. Bilateral ureteral obstruction downregulates expression of vasopressin-sensitive AQP-2 water channel in rat kidney
11. Nitric oxide inhibits ADH-stimulated osmotic water permeability in cortical collecting ducts
12. Mechanism of the nitric oxide-induced blockade of collecting duct water permeability
13. Changes in glomerular filtration rate during complete ureteral obstruction in rats
14. The pathogenesis of postobstructive diuresis. The role of circulating natriuretic and diuretic factors, including urea
15. Renal microcirculation and tissue damage during acute ureteral obstruction in the rat: Effect of saline infusion, indomethacin and radiocontrast
16. Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells
17. Pathophysiology of obstructive nephropathy. A 1991 update
18. Molecular physiology of urinary concentrating mechanism: Regulation of aquaporin water channels by vasopressin
19. Mechanism of vasopressin action in the renal collecting duct
20. Urinary concentration and dilution
21. Role of aquaporins in water balance disorders
22. Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: Prevention by alpha-MSH
23. Reduced AQP1, -2, and -3 levels in kidneys of rats with CRF induced by surgical reduction in renal mass
24. Nephrogenic diabetes insipidus in mice lacking aquaporin- 3 water channels
25. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels
26. Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla
27. Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex
28. Long-term regulation of aquaporins in the kidney
29. Redistribution of aquaporin-2 water channels induced by vasopressin in rat kidney inner medullary collecting duct
30. Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane
31. Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney
32. Physiology and pathophysiology of renal aquaporins
33. CHIP28 water channels are localized in constitutively water-permeable segments of the nephron
34. Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats
35. Changes in aquaporin-2 protein contribute to the urine concentrating defect in rats fed a low-protein diet
36. Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct
37. NaCl transport deficiencies-hemodynamics to the rescue
38. Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice
39. The role of the medullary collecting ducts in postobstructive diuresis
40. Nitric oxide inhibits sodium reabsorption in the isolated perfused cortical collecting duct
41. Effect of aging on vasopressin and aquaporin responses to dehydration in Fischer 344-brown-Norway F 1 rats
42. Long-term regulation of four renal aquaporins in rats
43. A micropuncture study of postobstructive diuresis in the rat