Role of aquaporins in water balance disorders

Current Opinion in Nephrology and Hypertension

Volumn 6, Issue 4, 1997, Pages 367-371

  Knepper, Mark A ^a,d   Verbalis, Joseph G ^b   Nielsen, Søren ^c  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c AARHUS UNIVERSITY   (Denmark)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN;

BASOLATERAL MEMBRANE; DIABETES INSIPIDUS; EXTRACELLULAR FLUID; FLUID BALANCE; HENLE LOOP; HUMAN; INAPPROPRIATE VASOPRESSIN SECRETION; KIDNEY COLLECTING TUBULE; OSMOSIS; PRIORITY JOURNAL; REVIEW; WATER PERMEABILITY; WATER TRANSPORT;

EID: 0030806511     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041552-199707000-00010     Document Type: Review

References (31)

1. Knepper MA, Rector FC Jr: Urinary concentration and dilution. In The Kidney, 5th edn. Edited by Brenner BM, Rector FC Jr. Philadelphia: Saunders; 1995:532-570.
2. Knepper MA: Molecular physiology of urinary concentrating mechanism: regulation of aquaporin water channels by vasopressin. Am J Physiol 1997, 272:F3-F12. An up-to-date review of the physiologic mechanisms of aquaporin regulation in the kidney is provided.
3. Knepper MA, Wade JB, Terris J, Ecelbarger CA, Marples D, Mandon B, Chou C-L, Kishore BK, Nielsen S: Renal aquaporins [Review]. Kidney Int 1996, 49:1712-1717.
4. Nielsen S, Agre P: The aquaporin family of water channels in kidney. Kidney Int 1995, 48:1057-1068.
5. Fushimi K, Uchida S, Hara Y, Hirata Y, Marumo F, Sasaki S: Cloning and expression of apical membrane water channel of rat kidney collecting tubule. Nature 1993, 361:549-552.
6. Nielsen S, DiGiovanni SR, Christensen El, Knepper MA, Hams HW: Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci USA 1993, 90:11663-11667.
7. Knepper MA, Nielsen S, Chou C-L, DiGiovanni SR: Mechanism of vasopressin action in the renal collecting duct. Semin Nephrol 1994, 14:302-321.
8. Nielsen S, Chou C-L, Marples D, Christensen El, Kishore BK, Knepper MA: Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane. Proc Natl Acad Sci USA 1995, 92:1013-1017. This article describes experiments combining immunoelectron microscopy and measurements of water transport in isolated perfused collecting ducts, demonstrating that vasopressin regulates collecting duct water permeability by triggering reversible trafficking of the aquaporin-2 water channel to the apical plasma membrane of collecting duct principal cells. Thus, the shuttle mechanism originally proposed by Wade et al, [11] was validated.
9. Sabolic I, Katsura T, Verbabatz JM, Brown D: The AQP2 water channel: effect of vasopressin treatment, microtubule disruption, and distribution in neonatal rats. J Membr Biol 1995, 143:165-177.
10. Yamamoto N, Sasaki S, Fushimi K, Ishibashi K, Yaiota E, Kawasaki K, Marumo F, Kihara I: Vasopressin increases AQP-CD water channel in the apical membrane of collecting duct cells without affecting AQP3 distribution in Brattleboro rat. Am J Physiol 1995, 268:C1546-C1551.
11. Wade JB, Stetson DL, Lewis SA: ADH action: evidence for a membrane shuttle mechanism. Ann N Y Acad Sci 1981, 372:106-117.
12. Lankford SP, Chou C-L, Terada Y, Wall SM, Wade JB, Knepper MA: Regulation of collecting duct water permeability independent of cAMP-mediated AVP response. Am J Physiol 1991, 261:F554-F566.
13. DiGiovanni SR, Nielsen S, Christensen El, Knepper MA: Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat. Proc Natl Acad Sci USA 1994, 91:8984-8988.
14. Ecelbarger CA, Terris J, Frindt G, Echevarria M, Marples D, Nielsen S, Knepper MA: Aquaporin-3 water channel localization and regulation in rat kidney. Am J Physiol 1995, 269:F663-F672.
15. Kishore BK, Terris JM, Knepper MA: Quantitation of aquaporin-2 abundance in microdissected collecting ducts: axial distribution and control by AVP. Am J Physiol 1996, 271:F62-F70.
16. Bichet DG: Vasopressin receptors in health and disease. Kidney Int 1996, 49:1706-1711.
17. Deen PM, Verdijk MA, Knoers NV, Wieringa B, Monnens LA, van Os CH, van Oost BA: Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of the urine. Science 1994, 264:92-95.
18. Marples D, Christensen S, Christensen El, Nielsen S: Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla. J Clin Invest 1995, 95:1838-1845. This article established the principle that long-term downregulation of aquaporin-2 expression can play a central role in acquired diabetes insipidus.
19. Marples D, Frokiaer J, Dorup J, Knepper MA, Nielsen S: Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex. J Clin Invest 1996, 97:1960-1968.
20. Frokiaer J, Marples D, Knepper MA, Nielsen S: Bilateral ureteral obstruction downregulates expression of the vasopressin sensitive aquaporin-2 water channel in rat kidney. Am J Physiol 1996, 270:F657-F668.
21. Froekiaer J, Marples D, Knepper MA, Nielsen S: Bilateral ureteral obstruction downregulates expression of the vasopressin sensitive aquaporin-2 water channel in rat kidney. Am J Physiol 1996, 270:F657-F668.
22. Fujita N, Ishikawa SE, Sasaki S, Fujisawa G, Fushimi K, Marumo F, Saito T: Role of water channel AQP-CD in water retention in SIADH and cirrhotic rats. Am J Physiol 1995, 269:F926-F931.
23. Levinsky NG, Davidson DG, Berliner RW: Changes in urine concentration during prolonged administration of vasopressin and water. Am J Physiol 1959, 196:451-456.
24. Ecelbarger CA, Nielsen S, Olson BR, Murase T, Baker EA, Knepper MA, Verbalis JG: Role of renal aquaporins in escape form vasopressin-induced antidiuresis in rat. J Clin Invest 1997, 99:1852-1863.
25. Terris J, Ecelbarger CA, Nielsen S, Knepper MA: Long-term regulation of four renal aquaporins in rat. Am J Physiol 1996, 271:F414-F422.
26. Xu D-L, Martin P-Y, Ohara M, St. John J, Pattison T, Meng X, Morris K, Kim JK, Schrier RW: Upregulation of aquaporin-2 water channel expression in chronic heart failure rat. J Clin Invest 1997, 99:1500-1505.
27. Nielsen S, Terris J, Andersen D, Ecelbarger C, Frokiaer J, Marples D, Knepper MA, Petersen JS: Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct. Proc Natl Acad Sci USA 1997, 94:5450-5455.
28. Asahina Y, Izumi N, Enomoto N, Sasaki S, Fushimi K, Marumo F, Sato C: Increased gene expression of water channel in cirrhotic rat kidneys. Hepatology 1995, 21:169-173.
29. Apostol E, Ecelbarger CA, Terris T, Bradford AD, Andrews P, Knepper MA: Reduced renal medullary water channel expression in puromycin aminonucleoside-induced nephrotic syndrome. J Am Soc Nephrol 1997, 8:15-24.
30. Preston GM, Agre P: Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family. Proc Natl Acad Sci USA 1991, 88:11110-11114.
31. Preston GM, Carroll TP, Guggino WP, Agre P: Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science 1992, 256:385-387.