Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice

Journal of Clinical Investigation

Volumn 103, Issue 4, 1999, Pages 491-496

  Chou, Chung Lin ^a   Knepper, Mark A ^a   Van Hoek, Alfred N ^b   Brown, Dennis ^b   Yang, Baoxue ^c   Ma, Tonghui ^c   Verkman, Alan S ^c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN;

ANIMAL TISSUE; ARTICLE; ELECTRON MICROSCOPY; FREEZE FRACTURE; HENLE LOOP; IMMUNOHISTOCHEMISTRY; KIDNEY CONCENTRATING CAPACITY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; ULTRASTRUCTURE; WATER PERMEABILITY; WATER TRANSPORT;

EID: 0033557374     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI5704     Document Type: Article

References (31)

1. Moore, L.C., and Marsh, D.J. 1980. How descending limb of Henle's loop permeability affects hypertonic urine formation. Am. J. Physiol. 239:F57-F71.
2. Stephenson, J.L., Jen, J.F., Wang, H., and Tewarson, R.P. 1995. Convective uphill transport of NaCl from ascending thin limb of loop of Henle. Am. J. Physiol. 268:F680-F692.
3. Gottschalk, C.W. 1964. Osmotic concentration and dilution of the urine. Am. J. Med. 36:670-684.
4. Imai, M., Taniguchi, J., and Tabei, K. 1987. Function of thin loops of Henle. Kidney Int. 31:565-579.
5. Miwa, T., and Imai, M. 1983. Flow-dependent water permeability of the rabbit descending limb of Henle's loop. Am. J. Physiol. 245:F743-F754.
6. Imai, M., and Yoshitomi, K. 1990. Heterogeneity of the descending thin limb of Henle's loop. Kidney Int. 38:687-694.
7. Chou, C.L., and Knepper, M.A. 1992. In vitro perfusion of chinchilla thin limb segments: segmentation and osmotic water permeability. Am. J. Physiol. 263:F417-F426.
8. Humbert, F., Pricam, C., Perrelet, A., and Orci, L. 1975. Freeze-fracture differences between plasma membranes of descending and ascending branches of the rat Henle's thin loop. Lab. Invest. 33:407-428.
9. Schiller, A., Taugner, R., and Kriz, W. 1980. The thin limbs of Henle's loop in the rabbit. Cell Tissue Res. 207:249-265.
10. Verbavatz, J.M., et al. 1993. Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes. A freeze-fracture study. J. Cell Biol. 123:605-618.
11. Verkman, A.S., et al. 1996. Water transport across mammalian cell membranes. Am. J. Physiol. 270:C12-C30.
12. Agre, P., et al. 1993. Aquaporin CHIP - the archetypal molecular water channel. Am. J. Physiol. 265:F463-F476.
13. Sabolic, I., et al. 1992. Localization of the CHIP28 water channel in rat kidney. Am. J. Physiol. 263:C1225-C1233.
14. Zhang, R., Skach, W, Hasegawa, H., van Hoek, A.N., and Verkman, A.S. 1993. Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28. J. Cell Biol. 120:359-369.
15. Nielsen, S., Smith, B.L., Christensen, E.I., Knepper, M.A., and Agre, P. 1993. CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. J. Cell Biol. 120:371-383.
16. Nielsen, S., et al. 1995. Aquaporin-1 water channels in short and long loop descending thin limbs and in descending vasa recta in rat kidney. Am. J. Physiol. 268:F1023-F1037.
17. Maeda, Y., Smith, B.L., Agre, P., and Knepper, M.A. 1995. Quantification of aquaporin-CHIP water channel protein in mirodissected renal tubules by fluorescence-based ELISA. J. Clin. Invest. 95:422-428.
18. Ma, T., et al. 1998. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J. Biol. Chem. 273:4296-4299.
19. Schnermann, J., et al. 1998. Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc. Natl. Acad. Sci. USA. 95:9660-9664.
20. Chou, C.L., Ma, T., Yang, B., Knepper, M.A., and Verkman, A.S. 1998. Four-fold reduction in water permeability in inner medullary collecting duct of aquaporin-4 knockout mice. Am. J. Physiol. 274:C549-C554.
21. Wall, S.M., Han, J.S., Chou, C.L., and Knepper, M.A. 1992. Kinetics of urea and water permeability activation by vasopressin in rat terminal IMCD. Am. J. Physiol. 262:F980-F998.
22. Orci, L., Humbert, F., Brown, D., and Perrelet, A. 1981. Membrane ultrastructure in urinary tubules. Int. Rev. Cytol. 73:183-242.
23. Shayakul, C., Knepper, M.A., Smith, C.P., DiGiovanni, S.R., and Hediger, M.A. 1997. Segmental localization of urea transporter mRNAs in rat kidney. Am. J. Physiol. 272:F654-F660.
24. Yang, B., and Verkman, A.S. 1998. Urea transporter UT3 functions as an efficient water channel: direct evidence for a common water/urea pathway. J. Biol. Chem. 273:9369-9372.
25. Ma, T., Yang, B., Kuo, W.L., and Verkman, A.S. 1996. cDNA cloning and gene structure of a new water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13. Genomics. 35:543-550.
26. Schwartz, M.M., and Venkatachalam, M.A. 1974. Structural differences in thin limbs of Henle: physiological implications. Kidney Int. 6:193-208.
27. Van Hoek, A.N., and Verkman, A.S. 1992. Functional reconstitution of the isolated erythrocyte water channel CHIP28. J. Biol. Chem. 267:18267-18269.
28. Dobbs, L., et al. 1998. Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc. Natl. Acad. Sci. USA. 95:2991-2996.
29. Roy, D.R., Layton, H.E., and Jamison, R.L. 1992. Countercurrent mechanism and its regulation. In The kidney: physiology and pathophysiology. D.W. Seldin and G. Giebisch, editors. Raven Press. New York, NY. 1649-1692.
30. Yang, B., and Verkman, A.S. 1997. Water and glycerol permeability of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J. Biol. Chem. 272:16140-16146.
31. Yang, B., Ma, T., Dong, J.Y., and Verkman, A.S. 1998. Partial correction of the urinary concentrating defect in AQP null mice by adenovirus-mediated AQP1 gene delivery. J. Am. Soc. Nephrol. 9:29a. (Abstr.)