Conformationally defined 6-s-trans-retinoic acid analogs. 3. Structure- activity relationships for nuclear receptor binding, transcriptional activity, and cancer chemopreventive activity

Journal of Medicinal Chemistry

Volumn 39, Issue 19, 1996, Pages 3625-3635

  Muccio, Donald D ^a   Brouillette, Wayne J ^a   Alam, Muzaffar ^a   Vaezi, Michael F ^a   Sani, Brahma P ^b   Venepally, Pratap ^b   Reddy, Lakshmi ^b   Li, Ellen ^c   Norris, Andrew W ^c   Simpson Herren, Linda ^b   Hill, Donald L ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; RETINOIC ACID; TRANSCRIPTION FACTOR;

ARTICLE; BINDING AFFINITY; CANCER PREVENTION; PROTEIN CONFORMATION; RECEPTOR BINDING; SKIN PAPILLOMA; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICARCINOGENIC AGENTS; CELL NUCLEUS; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PAPILLOMA; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; SKIN NEOPLASMS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 9544242711     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9603126     Document Type: Article

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