A variable dinuclelotide repeat in the CFTR gene contributes to phenotype diversity by forming RNA secondary structures that after splicing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 10, 2004, Pages 3504-3509

  Hefferon, Timothy W ^a   Groman, Joshua D ^a   Yurk, Catherine E ^a   Cutting, Garry R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; CFTR PROTEIN, HUMAN; COMPLEMENTARY DNA;

ARTICLE; BASE PAIRING; CYSTIC FIBROSIS; DINUCLEOTIDE REPEAT; EUKARYOTE; EXON; GENE EXPRESSION; GENETIC VARIABILITY; GENOME; HUMAN; HUMAN CELL; MALE INFERTILITY; PHENOTYPE; PRIORITY JOURNAL; RNA SPLICING; RNA STABILITY; RNA STRUCTURE; SIGNAL TRANSDUCTION; THERMODYNAMICS; VAS DEFERENS; CELL LINE; CHEMISTRY; CONFORMATION; CONGENITAL MALFORMATION; GENETICS; MALE; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS;

EUKARYOTA;

BASE SEQUENCE; CELL LINE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DINUCLEOTIDE REPEATS; DNA, COMPLEMENTARY; EXONS; HUMANS; MALE; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; PHENOTYPE; RNA; RNA SPLICING; RNA STABILITY; THERMODYNAMICS; VAS DEFERENS;

EID: 1542723471     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0400182101     Document Type: Article

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