Intratumoral heterogeneity in microsatellite alterations in BRCA1 and PTEN regions in sporadic colorectal cancer

Annals of Surgical Oncology

Volumn 10, Issue 8, 2003, Pages 876-881

  Garcia, Jose M ^a   Rodriguez, Rufo ^b   Silva, Javier ^a   Muñoz, Concepción ^b   Dominguez, Gemma ^a   Silva, Jose M ^a   Carcereny, Enric ^a   Provencio, Mariano ^a   España, Pilar ^a   Bonilla, Félix ^a  

^a HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^b HOSPITAL VIRGEN DE LA SALUD   (Spain)

Author keywords

BRCA1; Colorectal cancer; LOH; PTEN; Tumor heterogeneity

Indexed keywords

BRCA1 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYACRYLAMIDE; MICROSATELLITE DNA; PHOSPHATASE; PTEN PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGED; ARTICLE; CHROMOSOME 10Q; CHROMOSOME 17Q; COLORECTAL CANCER; CONTROLLED STUDY; ELECTROPHORESIS; FEMALE; GENE FREQUENCY; GENE LOCATION; GENETIC CORRELATION; GENETIC HETEROGENEITY; HETEROZYGOSITY LOSS; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; MUTATION; ONCOGENE; POLYMERASE CHAIN REACTION; SILVER STAINING; TUMOR GROWTH; CHI SQUARE DISTRIBUTION; CHROMOSOME 10; CHROMOSOME 17; COLORECTAL TUMOR; GENE DELETION; GENETICS; TUMOR SUPPRESSOR GENE;

AGED; CHI-SQUARE DISTRIBUTION; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 17; COLORECTAL NEOPLASMS; FEMALE; GENE DELETION; GENES, BRCA1; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; PHOSPHORIC MONOESTER HYDROLASES; POLYMERASE CHAIN REACTION; PTEN PHOSPHOHYDROLASE; TUMOR SUPPRESSOR PROTEINS;

EID: 1542649554     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1245/ASO.2003.02.004     Document Type: Article

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