Human embryonic stem cells - Realising the potential

Advances in Experimental Medicine and Biology

Volumn 534, Issue , 2003, Pages 11-25

  McWhir, Jim ^a   Thomson, Alison ^a   Sottile, Virginie ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CYTOLOGY; EMBRYONIC STEM CELL; HUMAN; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; REGENERATIVE MEDICINE; EMBRYO; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; ORGANOGENESIS; STEM CELL;

CELL DIFFERENTIATION; EMBRYO; HUMANS; IMMUNE TOLERANCE; ORGANOGENESIS; STEM CELLS;

EID: 1542647265     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0063-6_2     Document Type: Article

References (52)

1. Evans, M.J., and Kaufman, M., 1981, Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156.
2. Martin, G.R., 1981, Isolation of a pluripotential cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci USA 78, 7634-7638.
3. Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., Waknitz, M.A., Swiergiel, J.J., Marshall, V.S., and Jones, J.M. 1998, Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147.
4. Reubinoff, B.E., Pera, M.F., Fong, C., Trounson, A., and Bongso, A., 2000, Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nature Biotechnology 18, 399-404.
5. Lebkowski, J.S., Gold, J., Xu, C., Funk, W., Chiu, C., and Carpenter, M., 2001, Human embryonic stem cells: culture differentiation, and genetic modification for regenerative medicine applications. The Cancer J 7 (suppl.2), S83-S93.
6. Xu, C., Inokuma, M.S., Denham, J., Golds, K., Kundu, P., Gold, J.D., and Carpenter, M., 2001, Feeder-free growth of undifferentiated human embryonic stem cells. Nature Biotechnology 19, 971-974.
7. Richards, M., Fong, C., Chan, W., Wong, P., and Bongso, A., 2002, Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nature Biotechnology 20 (9), 933-936.
8. Zhang S., Wernig, M., Duncan, I.D., Brustle, O., and Thomson, J.A., 2001, In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nature Biotechnology 19, 1129-1133.
9. Reubinoff, B.E., Itsykson, P., Turetsky, T., Pera, M.F., Reinhartz, E., Itzik, A. and Ben-hur, T. 2001, Neural progenitors from human embryonic stem cells. Nature Biotechnology 19, 1134-1140.
10. Zhang, S-C., Ge, B., and Duncan I.D., 1999, Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity. Proc. Natl. Acad Sci. USA 96, 4089-4094.
11. Carpenter, M., Inokuma, M.S., Mujtaba, T., Chui, C.P., Rao, and M.S., 2001, Enrichment of neurons and neural precursors from human embryonic stem cells. Exper. Neur. 172, 383-397.
12. Xu, C., Police, S., Rao, N., and Carpenter, M.K., 2002, Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res. 91 (6), 501-508.
13. Kehat, I., Kenyagin-Karsenti, D., Snir, M., Segev, H., Amir, M., Gepstein, A., Livne, E., Binah, O., Itskovitz-Eldor, J., and Gepstein, L., 2002, Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J. Clin. Invest. 108, 407-414.
14. Schuldiner, M., Yanuka, O., Itskovitz-Eldor, J., Melton, D.A., and Benvenisty, N., 2000, Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci. USA. 97(21), 11307-11312.
15. Edwards, M.K., Harris, J.F., and McBurney, M.W., 1983, Induced muscle differentiation in an embryonal carcinoma cell line. Mol Cell Biol 3, 2280-2286.
16. Wobus, A.M., Kaomei, G., Shan, J., Wellner, M.C., Rohwedel, J., Ji, G., Fleischmann, B., Katus, H.A., Hescheler, J., and Franz, W.M., 1997, Retinoic acid accelerates embryonic stem cell-derived cardiac differentiation and enhances development of ventricular cardiomyocytes. J. Mol. Cell. Cardiol. 29, 1525-1539.
17. Assady, S., Maor, G., Amit, M., Itskovitz-Eldor, J., Skorecki, K.L., and Tzukerman, M., 2001, Insulin production by human embryonic stem cells. Diabetes 50, 1691-1697.
18. Rambhatla, L., Chui, C-P., Kundu, P., Peng, Y., and Carpernter, M.K., 2003, Generation of hepatocyte-like cells from human embryonic stem cells. Cell Transplantation (in press).
19. Levenberg, S., Golub, J.S., Amit, M., Itskovitz-Eldor, J., and Langer, R., 2002, Endothelial cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci. USA. 99(7), 4391-4396.
20. Kaufman, D.S., Hanson, E.T., Lewis, R.L., Auerbach, R., and Thomson, J.A., 2001, Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci USA. 19, 10716-10721.
21. Schuldiner, M., Yanuka, O., Itskovita-Eldor, J., Melton, D., and Benvenisty, N., 2000, Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci USA. 97 (2), 11307-11312.
22. Bianchi, G., Muraglia, A., Daga, A., Corte, G., Cancedda, R., and Quarto R. 2001, Microenvironment and stem cell properties of bone marrow-derived mesenchymal cells. Wound Repair and Regeneration. 9 (6), 460-466.
23. Ferrari, G. 1998, Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279, 528-530.
24. Gussoni, E., 1999, Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 401, 390-394.
25. Jackson, K., 1999, Regeneration of ischaemic cardiac muscle and vascular endothelium by adult stem cells. J. Clin. Invest. 107, 1395-1402.
26. Lin, Y., Weisdorf, D.J., Solovey, A., and Hebbel, R.P., 2000, Origins of circulating endothelial cells and endothelial outgrowth from blood. J. Clin. Invest. 105, 71-77.
27. Asahara, T., 1999, Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularisation. Circ. Res. 85, 221-228.
28. Petersen, B.E. 1999, Bone marrow as a potential source of hepatic oval cells. Science 284 1168-1170.
29. Theise, N.D., 2000, Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 31, 235-240.
30. Lagasse, E., 2001, Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nature Med. 6, 1229-1234.
31. Krause, D.S., 2001, Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 105, 369-377.
32. Kawada, H., and Ogawa, M., 2001, Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle. Blood 98, 2008-2013.
33. Clarke, D.L., 2000, Generalized potential of adult neural stem cells. Science 288, 1660-1663.
34. Digirolamo, C.M., Stokes, D., Colter, D., Phinney, D.G., Glass, R., and Prokop, D.J., 1999, Propoagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br. J. Haematol. 107 (2), 275-281.
35. Pittenger, M.F., MacKay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., Moorman, M.A., Simonetti, D.W., Crqaig, S., and Marshak, D.R., 1999, Multilineage potential of adult human mesenchymal stem cells. Science 284, 143-146.
36. Ying, Q.-L., Nichols, J., Evans, E.P., and Smith, A.G. 2002, Changing potency by spontaneous fusion. Nature 416, 545-547; advance online publication, 13 March 2002 (DOI 10.1038/nature729).
37. Tarada, N., Hamazaki, T., Oka, M., Hoki, M., Mastalerz, D. M., Nakano, Y., Meyer, E. M., Morel, L., Petersen, B. E., and Scott, E. W., 2002, Bone marrow cells adopt the phenotype of other cells by spontaneous fusion. Nature 416, 542-545; advance online publication, 13 March 2002 (DOI 10.1038/nature730).
38. Pells, S., Di Domenico, A.I., Gallagher, E.J., and McWhir, J., 2003, Multipotentiality of neuronal cells following spontaneous fusion with ES cells and nuclear reprogramming In Vitro Stem Cells and Cloning (in press).
39. Jiang, Y., Jahagirdar, B.N., Reinhard, R.L., Schwartz, R.E., Keene, C.D., Ortiz-Gonzalez, X., Reyes, M., Lenvik, T., Blackstad, M., Du, J., Aldrich, S., Lisberg, A., Low, W.C., Largaespada, D.A., and Verfaillie, C., 2002, Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418 (6893), 41-49.
40. Reyes, M., Lund, T., Lenvik, T., Aguir, D., Koodie, L. and Verfaillie, C.M., 2001, Purification and ex-vivo expansion of post natal human marrow mesodermal progenitor cells. Blood 98, 2615.
41. Jiang, Y., Vaessen, B., Lenvik, T., Blackstad, M., Reyes, M., and Verfaillie, C.M., 2002, Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle and brain. Experimental Hematology 30, 896-904.
42. Alvarez-Buylla A., and Garcia-Verdugo, J.M., 2002, Neurogenesis in adult subventricular zone. J. Neurosci. 22, 629-634.
43. Gage, F., 2002, Neurogenesis in adult brain. J. Neurosci. 22, 612-613.
44. Seaberg, R.M., and van der Kooy, D., 2002, Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells but the dentate gyrus contains restricted progenitors. J. Neurosci. 22, 1784-1793.
45. Clarke, D., Johansson, C., Wilbertz, J., Veress, B., Nilsson, E., Karlstrom, H., Lendahl, U., and Frisen, J., 2000, Generalized potential of adult neural stem cells Science 288, 1660-1663.
46. Bjornson, C., Rietze, R., Reynolds, B., Magli, M., and Vescovi, A., 1999, Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 283, 534-537.
47. Tortella, D., Gewurz, B.E., Furman, M.H., Schust, D.J., and Ploegh, H.L., 2000, Viral subversion of the immune system. Ann. Rev. Immunol. 18, 861-926.
48. Wekerle, T., Kurtz, J., Bigenzahn, S., Takeuchi, Y., and Sykes, M., 2002, Mechanisms of transplant tolerance induction using costimulatory blockade. Curr. Opinion in Immunol. 14, 592-600.
49. Wekerle, T., and Sykes M., 2001, Mixed chimerism and transplantation tolerance. Annu. Rev. Med. 52, 353-370.
50. Fandrich, F., Lin, X., Chai, G.X., Shulze, M., Ganten, D., Bader, M., Holle, J., Huang, D-S., Parwaresh, R., Zavazava, N., and Binas, B., 2002, Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning. Nature Med 8 (2), 171-178.
51. OsirisTherapeuticsInc.website.www.osiristx.com/ TechnologyATechnology_UniversalCell .ht
52. Verma, S., Rajaratnam, J.H., Denton, J., Hoyland, J.A., and Byers, R.J. 2002, Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis. J. Clin. Path. 55, 693-698.