Listeria monocytogenes virulence proteins induce surface expression of Fas ligand on T lymphocytes

Molecular Microbiology

Volumn 51, Issue 5, 2004, Pages 1483-1492

  Zenewicz, Lauren A ^a   Skinner, Jason A ^a   Goldfine, Howard ^a   Shen, Hao ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; LISTERIOLYSIN; LISTERIOLYSIN O; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE C; PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL SURFACE; CONTROLLED STUDY; IN VITRO STUDY; LISTERIA; LISTERIA INNOCUA; LISTERIA IVANOVII; LISTERIA MONOCYTOGENES; LISTERIOSIS; LYMPHOCYTE CULTURE; MODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; PURIFICATION; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TARGET CELL; UPREGULATION;

ANIMALS; BACTERIAL PROTEINS; CELL DEATH; CELLS, CULTURED; CYTOCHALASIN B; FAS LIGAND PROTEIN; LISTERIA MONOCYTOGENES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES; UP-REGULATION; VIRULENCE FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); LISTERIA; LISTERIA INNOCUA; LISTERIA IVANOVII; LISTERIA MONOCYTOGENES; MURINAE; POSIBACTERIA;

EID: 1542616346     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2003.03931.x     Document Type: Article

References (57)

1. Angelakopoulos, H., Loock, K., Sisul, D.M., Jensen, E.R., Miller, J.F., and Hohmann, E.L. (2002) Safety and shedding of an attenuated strain of Listeria monocytogenes with a deletion of actA/plcB in adult volunteers: a dose escalation study of oral inoculation. Infect Immun 70: 3592-3601.
2. Bossi, G., and Griffiths, G.M. (1999) Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells. Nature Med 5: 90-96.
3. Brennan, M.A., and Cookson, B.T. (2000) Salmonella induces macrophage death by caspase-1-dependent necrosis. Mol Microbiol 38: 31-40.
4. Camilli, A., Goldfine, H., and Portnoy, D.A. (1991) Listeria monocytogenes mutants lacking phosphatidylinositol-specific phosphollpase C are avirulent. J Exp Med 173: 751-754.
5. Camilli, A., Tilney, L.G., and Portnoy, D.A. (1993) Dual roles of plcA in Listeria monocytogenes pathogenesis. Mol Microbiol 8: 143-157.
6. Cantrell, D. (1996) T cell antigen receptor signal transduction pathways. Annu Rev Immunol 14: 259-274.
7. Conlan, J.W. (1996) Early pathogenesis of Listeria monocytogenes infection in the mouse spleen. J Med Microbiol 44: 295-302.
8. Cossart, P., Vicente, M.F., Mengaud, J., Baquero, F., Perez-Diaz, J.C., and Berche, P. (1989) Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation. Infect Immun 57: 3629-3636.
9. Daigle, I., Ruckert, B., Schnetzler, G., and Simon, H.U. (2000) Induction of the IL-10 gene via the fas receptor in monocytes - an anti-inflammatory mechanism in the absence of apoptosis. Eur J Immunol 30: 2991-2997.
10. Dube, P.H., Revell, P.A., Chaplin, D.D., Lorenz, R.G., and Miller, V.L. (2001) A role for IL-1α in inducing pathologic inflammation during bacterial infection. Proc Natl Acad Sci USA 98: 10880-10885.
11. 2+ signaling modulates cytolytic T lymphocyte effector functions. J Exp Med 187: 1057-1067.
12. Gedde, M.M., Higgins, D.E., Tilney, L.G., and Portnoy, D.A. (2000) Role of listeriolysin O in cell-to-cell spread of Listeria monocytogenes. Infect Immun 68: 999-1003.
13. Geoffroy, C., Raveneau, J., Beretti, J.L., Lecroisey, A., Vazquez-Boland, J.A., Alouf, J.E., and Berche, P. (1991) Purification and characterization of an extracellular 29-kilodalton phospholipase C from Listeria monocytogenes. Infect Immun 59: 2382-2388.
14. Glass, A., Walsh, C.M., Lynch, D.H., and Clark, W.R. (1996) Regulation of the Fas lytic pathway in cloned CTL. J Immunol 156: 3638-3644.
15. Goldfine, H., and Wadsworth, S.J. (2002) Macrophage intracellular signaling induced by Listeria monocytogenes. Microbes Infect 4: 1335-1343.
16. Goldfine, H., Johnston, N.C., and Knob, C. (1993) Non-specific phospholipase C of Listeria monocytogenes: activity on phospholipids in Triton X-100-mixed micelles and in biological membranes. J Bacteriol 175: 4298-4306.
17. Goldfine, H., Wadsworth, S.J., and Johnston, N.C. (2000) Activation of host phospholipases C and D in macrophages after infection with Listeria monocytogenes. Infect Immun 68: 5735-5741.
18. Gouin, E., Mengaud, J., and Cossart, P. (1994) The virulence gene cluster of Listeria monocytogenes is also present in Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a nonpathogenic species. Infect Immun 62: 3550-3553.
19. Hahne, M., Renno, T., Schroeter, M., Irmler, M., French, L., Bornard, T., et al. (1996) Activated B cells express functional Fas ligand. Eur J Immunol 26: 721-724.
20. Jensen, E.R. (1998) Recombinant Listeria monocytogenes as a live vaccine vector and a probe for studying cell-mediated immunity. Microbiology and immunology. Los Angeles: University of California - Los Angeles, 163 pp.
21. Jones, S., and Portnoy, D.A. (1994) Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O. Infect Immun 62: 5608-5613.
22. Kasibhatla, S., Brunner, T., Genestier, L., Echeverri, F., Mahboubi, A., and Green, D.R. (1998) DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1. Mol Cell 1: 543-551.
23. Kaufmann, S.H., and Ladel, C.H. (1994) Role of T cell subsets in immunity against intracellular bacteria: experimental infections of knock-out mice with Listeria monocytogenes and Mycobacterium bovis BCG. Immunobiology 191:509-519.
24. Kiener, P.A., Davis, P.M., Rankin, B.M., Klebanoff, S.J., Ledbetter, J.A., Starling, G.C., and Liles, W.C. (1997) Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. J Immunol 159: 1594-1598.
25. Kocks, C., Gouin, E., Tabouret, M., Berche, P., Ohayon, H., and Cossart, P. (1992) L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein. Cell 68: 521-531.
26. Kojima, Y., Kawasaki-Koyanagi, A., Sueyoshi, N., Kanai, A., Yagita, H., and Okumura, K. (2002) Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity. Biochem Biophys Res Commun 296: 328-336.
27. Leimeister-Wachter, M., Goebel, W., and Chakraborty, T. (1989) Mutations affecting hemolysin production in Listeria monocytogenes located outside the listeriolysin gene. FEMS Microbiol Lett 53: 23-29.
28. Leimeister-Wachter, M., Domann, E., and Chakraborty, T. (1991) Detection of a gene encoding a phosphatidylinositol-specific phospholipase C that is co-ordinately expressed with listeriolysin in Listeria monocytogenes. Mol Microbiol 5: 361-366.
29. Liles, W.C., Kiener, P.A., Ledbetter, J.A., Aruffo, A., and Klebanoff, S.J. (1996) Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils. J Exp Med 184: 429-440.
30. Mackaness, G.B. (1962) Cellular resistance to infection. J Exp Med 116: 381-406.
31. Marquis, H., Goldfine, H., and Portnoy, D.A. (1997) Proteolytic pathways of activation and degradation of a bacterial phospholipase C during intracellular infection by Listeria monocytogenes. J Cell Biol 137: 1381-1392.
32. Matzinger, P. (1991) The JAM test. A simple assay for DNA fragmentation and cell death. J Immunol Methods 145: 185-192.
33. Mengaud, J., Braun-Breton, C., and Cossart, P. (1991) Identification of phosphatidylinositol-specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor? Mol Microbiol 5: 367-372.
34. Merrick, J.C., Edelson, B.T., Bhardwaj, V., Swanson, P.E., and Unanue, E.R. (1997) Lymphocyte apoptosis during early phase of Listeria infection in mice. Am J Pathol 151: 785-792.
35. Mielke, M.E., Niedobitek, G., Stein, H., and Hahn, H. (1989) Acquired resistance to Listeria monocytogenes is mediated by Lyt-2+ T cells independently of the influx of monocytes into granulomatous lesions. J Exp Med 170: 589-594.
36. Miwa, K., Asano, M., Horai, R., Iwakura, Y., Nagata, S., and Suda, T. (1998) Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand. Nature Med 4: 1287-1292.
37. Mustafa, T., Bjune, T.G., Jonsson, R., Pando, R.H., and Nilsen, R. (2001) Increased expression of Fas ligand in human tuberculosis and leprosy lesions: a potential novel mechanism of immune evasion in mycobacterial infection. Scand J Immunol 54: 630-639.
38. Portnoy, D.A., Jacks, P.S., and Hinrichs, D.J. (1988) Role of hemolysin for the intracellular growth of Listeria monocytogenes. J Exp Med 167: 1459-1471.
39. Portnoy, D.A., Auerbuch, V., and Glomski, I.J. (2002) The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J Cell Biol 158: 409-414.
40. 2+ oscillations. Cell Microbiol 4: 483-491.
41. Sansonetti, P.J., Phalipon, A., Arondel, J., Thirumalai, K., Banerjee, S., Akira, S., et al. (2000) Caspase-1 activation of IL-1β and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity 12: 581-590.
42. Sibelius, U., Rose, F., Chakraborty, T., Darji, A., Wehland, J., Weiss, S., et al. (1996) Listeriolysin is a potent inducer of the phosphatidylinositol response and lipid mediator generation in human endothelial cells. Infect Immun 64: 674-676.
43. Smith, G.A., Marquis, H., Jones, S., Johnston, N.C., Portnoy, D.A., and Goldfine, H. (1995) The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread. Infect Immun 63: 4231-4237.
44. Stalder, T., Hahn, S., and Erb, P. (1994) Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J Immunol 152: 1127-1133.
45. Suda, T., and Nagata, S. (1994) Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 179: 873-879.
46. Suda, T., Okazaki, T., Naito, Y., Yokota, T., Arai, N., Ozaki, S., et al. (1995) Expression of the Fas ligand in cells of T cell lineage. J Immunol 154: 3806-3813.
47. Tilney, L.G., and Portnoy, D.A. (1989) Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes. J Cell Biol 109: 1597-1608.
48. Ullrich, H.J., Beatty, W.L., and Russell, D.G. (2000) Interaction of Mycobacterium avium-containing phagosomes with the antigen presentation pathway. J Immunol 165: 6073-6080.
49. Unanue, E.R. (1997) Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance. Curr Opin Immunol 9: 35-43.
50. Vazquez-Boland, J.A., Kocks, C., Dramsi, S., Ohayon, H., Geoffroy, C., Mengaud, J., and Cossart, P. (1992) Nucleotide sequence of the lecithinase operon of Listeria monocytogenes and possible role of lecithinase in cell-to-cell spread. Infect Immun 60: 219-230.
51. Vazquez-Boland, J.A., Dominguez-Bernal, G., Gonzalez-Zorn, B., Kreft, J., and Goebel, W. (2001) Pathogenicity islands and virulence evolution in Listeria. Microbes Infect 3: 571-584.
52. Wadsworth, S.J., and Goldfine, H. (1999) Listeria monocytogenes phospholipase C-dependent calcium signaling modulates bacterial entry into J774 macrophage-like cells. Infect Immun 67: 1770-1778.
53. Wadsworth, S.J., and Goldfine, H. (2002) Mobilization of protein kinase C in macrophages induced by Listeria monocytogenes affects its internalization and escape from the phagosome. Infect Immun 70: 4650-4660.
54. Wang, J., Brooks, E.G., Bamford, K.B., Denning, T.L., Pappo, J., and Ernst, P.B. (2001) Negative selection of T cells by Helicobacter pylori as a model for bacterial strain selection by immune evasion. J Immunol 167: 926-934.
55. Watanabe-Fukunaga, R., Brannan, C.I., Itoh, N., Yonehara, S., Copeland, N.G., Jenkins, N.A., and Nagata, S. (1992) The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol 148: 1274-1279.
56. Yao, T., Mecsas, J., Healy, J.I., Falkow, S., and Chien, Y. (1999) Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH. J Exp Med 190: 1343-1350.
57. Zückert, W.R., Marquis, H., and Goldfine, H. (1998) Modulation of enzymatic activity and biological function of Listeria monocytogenes broad-range phospholipase C by amino acid substitutions and by replacement with the Bacillus cereus ortholog. Infect Immun 66: 4823-4831.