Safety and shedding of an attenuated strain of Listeria monocytogenes with a deletion of actA/plcB in adult volunteers: A dose escalation study of oral inoculation

Infection and Immunity

Volumn 70, Issue 7, 2002, Pages 3592-3601

  Angelakopoulos, Haroula ^a   Loock, Katharina ^a   Sisul, David M ^a   Jensen, Eric R ^a   Miller, Jeff F ^a   Hohmann, Elizabeth L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; GENE PRODUCT; LH 1169; PROTEIN ACTA; PROTEIN PLCB; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BACTEREMIA; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BLOOD CULTURE; CELLULAR IMMUNITY; CLINICAL FEATURE; CLINICAL TRIAL; COLONY FORMING UNIT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; FECES CULTURE; FEVER; GENE DELETION; HUMAN; HUMAN EXPERIMENT; HUMORAL IMMUNITY; INOCULATION; LISTERIA MONOCYTOGENES; LIVER FUNCTION TEST; NONVIRAL GENE DELIVERY SYSTEM; NORMAL HUMAN; OUTPATIENT CARE; PATHOGENICITY; PATIENT MONITORING; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; CONSUMER PRODUCT SAFETY; FECES; FEMALE; GENES, BACTERIAL; GENETIC VECTORS; HUMAN EXPERIMENTATION; HUMANS; INTERFERON TYPE II; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; MALE; MEMBRANE PROTEINS; MUTAGENESIS; PHOSPHOLIPASE C; T-LYMPHOCYTES; VACCINES, ATTENUATED;

EID: 0036087666     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.7.3592-3601.2002     Document Type: Article

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