Dentin matrix proteins and soluble factors: Intrinsic regulatory signals for healing and resorption of dental and periodontal tissues?

Oral Diseases

Volumn 10, Issue 2, 2004, Pages 63-74

  Silva, Tarcìlia Aparecida ^a   Rosa, A L ^a   Lara, V S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bone cells; Bone resorption; Cytokines; Dental resorption; Dentin; Periodontal healing

Indexed keywords

EPIDERMAL GROWTH FACTOR; GELATINASE A; MATRIX PROTEIN; OSTEOPONTIN; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN B; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; VASCULOTROPIN;

AMINO ACID SEQUENCE; BONE MINERALIZATION; CELL ADHESION; CELL GROWTH; CELL MIGRATION; DEMINERALIZATION; DENTIN; EXTRACELLULAR MATRIX; HUMAN; INFLAMMATORY CELL; MINERALIZATION; NONHUMAN; ORTHODONTICS; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PERIODONTAL DISEASE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; TOOTH DISEASE; WOUND HEALING;

ANIMALS; BONE REMODELING; CELL ADHESION; DENTIN; EXTRACELLULAR MATRIX PROTEINS; GROWTH SUBSTANCES; HUMANS; INFLAMMATION MEDIATORS; PERIODONTIUM; REGENERATION; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 1542572647     PISSN: 1354523X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2004.00992.x     Document Type: Review

References (117)

1. Bang G (1972). Induction of heterotopic bone formation by demineralized dentin in guinea pigs: antigenicity of the dentin matrix. J Oral Pathol 1: 172-185.
2. Bang G, Urist MR (1967). Bone induction in excavation chambers in matrix of decalcified dentin. Arch Surg 94: 781-789.
3. 45Ca release and osteoclast differentiation and migration. Eur J Orthod 16: 130-137.
4. Bessho K, Tagawa T, Murata M (1990). Purification of rabbit bone morphogenetic protein derived from bone, dentin, and wound tissue after tooth extraction. J Oral Maxillofac Surg 48: 162-169.
5. Bessho K, Tanaka N, Matsumoto J et al (1991). Human dentin-matrix-derived bone morphogenetic protein. J Dent Res 70: 171-175.
6. Bodine PVN, Komn BS (1999). Evidence that conditionally immortalized human osteoblasts express an osteocalcin receptor. Bone 25: 535-543.
7. Booth V, Young S, Cruchley A et al (1998). Vascular endothelial growth factor in human periodontal disease. J Periodontal Res 33: 491-499.
8. Boskey AL, Gadlaleta S, Gundberg C et al (1998). Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin. Bone 23: 187-196.
9. Butler WT (1998). Dentin matrix proteins. Eur J Oral Sci 106 (Suppl. 1): 204-1210.
10. Butler WT, Bhown M, Brunn JC et al (1992). Isolation, characterization and immunolocalization of a 53-kDal dentin sialoprotein (DSP). Matrix 12: 343-351.
11. Cassidy N, Fahey M, Prime SS et al (1997). Comparative analysis of transforming growth factor β isoforms 1-3 in human and rabbit dentin matrices. Arch Oral Biol 42: 219-223.
12. Chenu C, Pfeilschlifter J, Mundy GR et al (1988). Transforming growth factor β inhibits formation of osteoclast-like cells in long-term human marrow cultures. Proc Natl Acad Sci USA 85: 5683-5687.
13. Chenu C, Colucci S, Grano M et al (1994). Osteocalcin induces chemotaxis, secretion of matrix proteins, and calcium-mediated intracellular signaling in human osteoclast-like cells. J Cell Biol 127: 1149-1158.
14. Collin-Osdoby P, Rothe L, Bekker S et al (2002). Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro. J Bone Miner Res 17: 1859-1871.
15. Denhardt DT, Noda M (1998). Osteopontin expression and function role in bone remodeling. J Cell Biochem 30-31 (Suppl.):92-102.
16. Denhardt DT, Noda M, O'Reagan AW et al (2001). Osteopontin as means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 107: 1055-1061.
17. Dodds RA, Connor JR, James IE et al (1995). Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: an in vitro and ex vivo study of remodeling bone. J Bone Miner Res 10: 1666-1680.
18. Domon S, Shimokawa H, Matsumoto Y et al (1999). In situ hybridization for matrix metalloproteinase-1 and cathepsin K in rat root-resorbing tissue induced by tooth movement. Arch Oral Biol 44: 907-915.
19. Ducy P, Desbois C, Boyce B et al (1996). Increased bone formation in osteocalcin-deficient mice. Nature 382: 448-452.
20. Dunstan CR, Boyce R, Boyce BF et al (1999). Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats. J Bone Miner Res 14: 953-959.
21. Ejeil AL, Igondjo-Tchen S, Ghomrasseni S et al (2003). Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in healthy and diseased human gingiva. J Periodontol 74: 188-195.
22. Finkelman RD (1992). Growth factors in bones and teeth. J Calif Dent Assoc 20: 23-29.
23. Finkelman RD, Mohan S, Jennings JC et al (1990). Quantification of growth factors IGF-I, SGF/IGFII and TGF-beta in human dentin. J Bone Miner Res 5: 717-723.
24. Fujisawa R, Butler WT, Brunn JC et al (1993). Differences in composition of cell-attachment sialoproteins between dentin and bone. J Dent Res 72: 1222-1226.
25. Gao Y, Yang L, Fang YR et al (1995). The inductive effect of bone morphogenetic protein (BMP) on human periodontal fibroblast-like cells in vitro. J Osaka Dent Univ 29: 9-17.
26. Giachelli CM, Lombardi D, Johnson RJ et al (1998). Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo. Am J Pathol 152: 353-358.
27. Glowacki J, Rey C, Glimcher MJ et al (1991). A role for osteocalcin in osteoclast differentiation. J Cell Biochem 45: 292-302.
28. Graves DT, Valentin-Opran A, Delgado R et al (1989). The potential role of platelet-derived growth factors as an autocrine and paracrine factor for human bone cells. Connect Tissue Res 23: 209-218.
29. Hasegawa N, Kawaguchi H, Ogawa T et al (2003). Immunohistochemical characteristics of epithelial cell rests of Malassez during cementum repair. J Periodontal Res 38: 51-56.
30. Hentunen TA, Lakkakorpi PT, Tuukknen J et al (1995). Effects of recombinant human osteogenic protein-1 on the differentiation of osteoblast-like cells and bone resorption. Biochem Biophys Res Commun 209: 433-443.
31. Heras SM-D, Valenzuela A, Overall CM (2000). The matrix metalloproteinase gelatinase A in human dentine. Arch Oral Biol 45: 757-765.
32. Hill PA, Reynolds JJ, Meikle MC (1995). Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function. Endocrinology 136: 124-131.
33. Hock JM, Centrella M, Canalis E (1988). Insulin-like growth factor I (IGF-I) has independent effects on bone matrix formation and cell replication. Endocrinology 122: 254-260.
34. Hoffmann A, Weich HA, Gross G et al (2001). Perspectives in the biological function, the technical and therapeutic application of bone morphogenetic proteins. Appl Microbiol Biotechnol 57: 294-308.
35. Huggins C, Wiseman S, Reddi AH (1970). Transformation of fibroblasts by allogenic and xenogenic transplants of demineralized tooth and bone. J Exp Med 132: 1250-1258.
36. Hurley MM, Lee SK, Raisz LG et al (1998). Basic fibroblast growth factor induces osteoclast formation in murine bone marrow cultures. Bone 22: 309-316.
37. Ingram RT, Clarke BL, Fisher LW et al (1993). Distribution of noncollagenous proteins in matrix of adult human bone: evidence of anatomic and functional heterogeneity. J Bone Miner Res 8: 1019-1029.
38. Inoue T, Deporter DA, Melcher AH (1986). Induction of chondrogenesis in muscle, skin, bone marrow and periodontal ligament by demineralized dentin and bone matrix in vivo and in vitro. J Dent Res 65: 12-22.
39. Inoue T, Chen SH, Shimono M (1990). Induction of cartilage and bone formation by cells from explants of various oral tissues in vitro. Bull Tokyo Dent Coll 31: 295-300.
40. Ivanovski S, Haase HR, Bartold PM (2001). Expression of bone matrix protein mRNAs by primary and cloned cultures of the regenerative phenotype of human periodontal fibroblasts. J Dent Res 80: 1665-1671.
41. Jain A, Karadag A, Fohr B et al (2002). Three SIBLINGs (small integrin-binding ligand, N-linked glycoproteins) enhance factor H's cofactor activity enabling MCP-like cellular evasion of complement-mediated attack. J Biol Chem 277: 13700-13708.
42. Johnson RB, Serio FG, Dai X (1999). Vascular endothelial growth factors and progression of periodontal diseases. J Periodontol 70: 848-852.
43. Kanatani M, Sugimoto T, Kaji H et al (1995). Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone resorbing activity. J Bone Miner Res 10: 1681-1690.
44. Kanzaki H, Chiba M, Shimizu Y et al (2001). Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. J Dent Res 80: 887-891.
45. Kawaguchi H, Chikazu D, Nakamura K et al (2000). Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures. J Bone Miner Res 15: 466-473.
46. Kawai T, Urist MR (1989). Bovine tooth-derived bone morphogenetic protein. J Dent Res 68: 1069-1074.
47. King GN, Cochran DL (2002). Factors that modulate the effects of bone morphogenetic protein-induced periodontal regeneration: a critical review. J Periodontol 73: 925-936.
48. King GN, Hughes FJ (2001). Bone morphogenetic protein-2 stimulates cell recruitment and cementogenesis during early wound healing. J Clin Periodontol 28: 465-475.
49. Koide M, Murase Y, Yamato K et al (1999). Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1α through upregulation of osteoclast differentiation factor and cyclooxygenase-2. Biochem Biophys Res Commun 259: 97-102.
50. Lara VS, Figueiredo F, Silva TA et al (2003). Dentin induced in vivo inflammatory response and in vitro activation of murine macrophages. J Dent Res 82: 460-465.
51. Levin LG, Rudd A, Bletsa A et al (1999). Expression of IL-8 by cells of the odontoblast layer in vitro. Eur J Oral Sci 107: 131-137.
52. Liggett WH, Lian JB, Greenberger JS et al (1994). Osteocalcin promotes differentiation of osteoclast progenitors from murine long-term bone marrow cultures. J Cell Biochem 55: 190-199.
53. Linde, A (1989). Dentin matrix proteins: composition and possible functions in calcification. Anat Rec 224: 154-166.
54. Linsuwanont B, Takagi Y, Ohya K et al (2002). Expression of matrix metalloproteinase-9 mRNA and protein during deciduous tooth resorption in bovine odontoclasts. Bone 31: 472-478.
55. Locklin RM, Oreffo ROC, Triffitt JT (1999). Effects of TGF and bFGF on the differentiation of human bone marrow stromal fibroblasts. Cell Biol Int 23: 185-194.
56. Malone JD, Teitelbaum SL, Griffin GL et al (1982). Recruitment of osteoclast precursors by purified bone matrix constituents. J Cell Biol 92: 227-230.
57. Matsuda N, Lin WL, Kumar NM et al (1992). Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontol 63: 515-525.
58. Matsuda N, Kumar NM, Ramakrishnan PR et al (1993). Evidence for up-regulation of epidermal growth factor receptors on rat periodontal ligament fibroblast cells associated with stabilization of phenotype in vitro. Arch Oral Biol 38: 559-569.
59. Miki Y, Narayanan AS, Page RC (1987). Mitogenic activity of cementum components to gingival fibroblasts. J Dent Res 66: 1399-1403.
60. Mincer HH, Jennings BR (1970). Morphologic and immunologic studies of subcutaneous incisor allografts in mice. J Dent Res 49: 381-388.
61. Mochizuki H, Hakeda Y, Wakatsuki N et al (1992). Insulin-like growth factor-I supports formation and activation of osteoclasts. Endocrinology 131: 1075-1080.
62. Mumford JH, Carnes DL, Cochran DL et al (2001). The effects of platelet-derived growth factor-BB on periodontal cells in an in vitro wound model. J Periodontol 72: 331-340.
63. Mundy GR, Varani J, Orr W et al (1978). Resorbing bone is chemotactic for monocytes. Nature 275: 132-135.
64. Murakami S, Takayama S, Ikezawa K et al (1999). Regeneration of periodontal tissues by basic fibroblast growth factor. J Periodontal Res 34: 425-430.
65. Nakagawa N, Yasuda H, Yano K et al (1999). Basic fibroblast growth factor induces osteoclast formation by reciprocally regulating the production of osteoclast differentiation factor and osteoclastogenesis inhibitory factor in mouse osteoclastic cells. Biochem Biophys Res Commun 265: 158-163.
66. Nakagawa M, Kaneda T, Arakawa T et al (2000). Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts. FEBS Lett 473: 161-164.
67. Ne RF, Whiterspoon DE, Gutmann JL (1999). Tooth resorption. Quintessence Int 30: 9-25.
68. Nebgen DR, Inoue H, Sabsay B et al (1999). Identification of the chondrogenic-inducing activity from bovine dentin (bCIA) as a low-molecular-mass amelogenin polypeptide. J Dent Res 78: 1484-1494.
69. Nesbitt SA, Horton MA (1997). Trafficking of matrix collagens through bone-resorbing osteoclasts. Science 276: 266-269.
70. Ng KT, King GJ, Courts FJ (1990). Humoral immune response to active root resorption with a murine model. Am J Orthod Dentofacial Orthop 98: 456-462.
71. Niida S, Kaku M, Amano H et al (1999). Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med 190: 293-298.
72. Nishimura K, Hayashi M, Matsuda K et al (1989). The chemoattractive potency of periodontal ligament, cementum and dentin for human gingival fibroblasts. J Periodontal Res 24: 146-148.
73. Noda M, Camilliere JJ (1989). In vivo stimulation of bone formation by transforming growth factor β. Endocrinology 124: 2991-2994.
74. Dgata Y, Niisato N, Moriwaki K et al (1997). Cementum, root dentin and bone extracts stimulate chemotactic behavior in cells from periodontal tissue. Comp Biochem Physiol 116: 359-365.
75. Palosaari H, Wahlgren J, Larmas M et al (2000). Expression of MMP-8 in human odontoblasts and dental pulp cells is down-regulated by TGF-β-1. J Dent Res 79: 77-84.
76. Parkar MH, Kuru L, Giouzeli M et al (2001). Expression of growth-factor receptors in normal and regenerating human periodontal cells. Arch Oral Biol 46: 275-284.
77. Qin C, Brunn JC, Cadena E et al (2002). The expression of dentin sialophosphoprotein gene in bone. J Dent Res 81: 392-394.
78. Rabinowitz T, Syftestad GT, Caplan AI (1990). Chondrogenic stimulation of embryonic chick limb mesenchymal cells by factors in bovine and human dentin extracts. Arch Oral Biol 35: 49-54.
79. Rani CSS, MacDougall M (2000). Dental cells express factors that regulate bone resorption. Mol Cell Biol Res Commun 3: 145-152.
80. Raynal C, Delmas PD, Chenu C (1996). Bone sialoprotein stimulates in vitro bone resorption. Endocrinology 137: 2347-2354.
81. Razzouk S, Brunn JC, Qin C et al (2002). Osteopontin posttranslational modifications, possibly phosphorylation, are required for in vitro bone resorption but not osteoclast adhesion. Bone 30: 40-47.
82. Ripamonti U, Heliotis M, Rueger DC et al (1996). Induction of cementogenesis by recombinant human osteogenic protein-1 (hop-1/bmp-7) in the baboon (Papio ursinus). Arch Oral Biol 41: 121-126.
83. Riviere GR, Hansen RW (1973). Alloantibodies induced in histoincompatible rats by single pulp and tooth grafts. J Dent Res 52: 11186-1188.
84. Roberts-Clark DJ, Smith AJ (2000). Angiogenic growth factors in human dentine matrix. Arch Oral Biol 45: 1013-1016.
85. Sakata M, Shiba H, Komatsuzawa H et al (1999). Expression of osteoprotegerin (osteoclastogenesis inhibitory factor) in cultures of human dental mesenchymal cells and epithelial cells. J Bone Miner Res 14: 1486-1492.
86. Sato M, Grasser W, Harm S et al (1992). Bone acid glycoprotein 75 inhibits resorption activity of isolated rat and chicken osteoclasts. FASEB J 6: 2966-2976.
87. Saygin NE, Tokiyasu Y, Giannobile WV et al (2000). Growth factors regulate expression of mineral associated genes in cementoblasts. J Periodontol 71: 1591-1600.
88. Scheven BAA, Marshall D, Aspden RM (2002). In vitro behaviour of human osteoblasts on dentin and bone. Cell Biol Int 26: 337-346.
89. Schwartz, O (1983). Cell-mediated and humoral alloimmune reactions after subperiosteal implantation of allogenic demineralized dentin in humans. Int J Oral Surg 12: 95-105.
90. Schwartz Z, Lohmann CH, Wieland M et al (2000). Osteoblast proliferation and differentiation on dentin slices are modulated by pretreatment of the surface with tetracycline or osteoclasts. J Periodontol 71: 586-597.
91. Smith AJ, Lesot H (2001). Induction and regulation of crown dentinogenesis: embryonic events as a template for dental tissue repair? Grit Rev Oral Biol Med 12: 425-437.
92. Somerman MJ, Archer SY, Hassell TM et al (1987a). Enhancement by extracts of mineralized tissues of protein production by human gingival fibroblasts in vitro. Arch Oral Biol 32: 879-883.
93. Somerman MJ, Perez-Mera M, Merkhofer RM et al (1987b). In vitro evaluation of extracts of mineralized tissues for their application in attachment of fibrous tissue. J Periodontol 58: 349-351.
94. Somerman MJ, Foster RA, Imm GM et al (1989). Periodontal ligament cells and gingival fibroblasts respond differently to attachment factors in vitro. J Periodontol 60: 73-77.
95. Steinsvoll S, Halstensen TS, Schenck K (1999). Extensive expression of TGF-beta1 in chronically-inflamed periodontal tissue. J Clin Periodontol 26: 366-373.
96. Takata T, D'Errico JA, Atkins KB et al (1998). Protein extracts of dentin affect proliferation and differentiation of osteoprogenitor cells in vitro. J Periodontol 69: 1247-1255.
97. Takayama S, Murakami S, Nozaki T et al (1998). Expression of receptors for basic fibroblast growth factor on human periodontal ligament cells. J Periodontal Res 33: 315-322.
98. Tashjian AH, Jr, Hohmann EL, Antoniades HN et al (1982). Platelet-derived growth factor stimulates bone resorption via a prostaglandin-mediated mechanism. Endocrinology 111: 118-124.
99. Tenorio D, Foyle DM, Hughes FJ (1997). The modulatory role of cementum matrix on osteoblastic cells in vitro. J Periodontal Res 32: 362-374.
100. Terranova VP, Odziemiec C, Tweden KS et al (1989). Repopulation of dentin surfaces by periodontal ligament cells and endothelial cells: effect of basic fibroblast growth factor. J Periodontol 60: 293-301.
101. Thomadakis G, Ramoshebi LN, Crooks J et al (1999). Immunolocalization of bone morphogenetic protein-2 and -3 and osteogenic protein-1 during murine tooth root morphogenesis and in other craniofacial structures. Eur J Oral Sci 107: 368-377.
102. Tjäderhane L, Salo T, Larjava H et al (1998). A novel organ culture method to study the function of the human odontoblasts in vitro: gelatinase expression by odontoblasts is differentially regulated by TGF-β-1. J Dent Res 77: 1488-1498.
103. Tompkins K, Veis A (2001). Amelogenin gene splice product [A-4] binds to embryonic fibroblasts in vitro. J Dent Res 80: 242 (Abstract).
104. Tsahjian AH, Levine L (1978). Epidermal growth factor stimulated prostaglandin production and bone resorption in cultured mouse calvaria. Biochem Biophys Res Commun 85: 966-975.
105. Tsahjian AH, Voelkel EF, Lazzaro M et al (1985). Alpha and beta transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria. Proc Natl Acad Sci 82: 4535-4538.
106. Urist MR, Strates BS (1971). Bone morphogenetic protein. J Dent Res 50: 1392-1406.
107. Veis A, Sires B, Clohisy J (1989). A search for the osteogenic factor in dentin. Rat incisor dentin contains a factor stimulating rat muscle cells in vitro to incorporate sulfate into an altered proteoglycan. Connect Tissue Res 23: 137-144.
108. Veis A, Sires B, Clohisy J et al (1990). Rat incisor dentine contains a factor which alters the phenotypic expression and stimulates chondrogenesis in fibroblast-like cells in vitro. Biomaterials 11: 35-37.
109. Veis A, Tompkins K, Alvares K et al (2000). Specific amelogenin gene splice products have signaling effects on cells in culture and in implants in vivo. J Biol Chem 275: 41263-41272.
110. Wahl SM, Allen JB, Costa GL et al (1993a). Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta. J Exp Med 177: 225-230.
111. Wahl SM, Costa GL, Mizel DE et al (1993b). Role of transforming growth beta in pathophysiology of chronic inflammation. J Periodontol 64: 450-455.
112. Wheeler TT, Stroup SE (1993). Traumatic root resorption in dentine-immunized mice. Am J Orthod Dentofacial Orthop 103: 352-357.
113. Yamaguchi A, Komori T, Suda T (2000). Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs and cbfa1. Endocr Rev 21: 393-411.
114. Yoemans JD, Urist MR (1967). Bone induction by decalcified dentin implanted into oral osseous and muscle tissues. Arch Oral Biol 12: 999-1008.
115. Zhao WG, Byrne MH, Boyce BF et al (1999). Bone resorption induced by parathyroid hormone is strikingly diminished by parathyroid hormone in collagenase resistant mutant mice. J Clin Invest 103: 517-524.
116. Zhao M, Berry JE, Somerman MJ (2003). Bone morphogenetic protein-2 inhibits differentiation and mineralization of cementoblasts in vitro. J Dent Res 82: 23-27.
117. Zhou HY, Takita H, Fujisawa R et al (1995). Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells. Calcif Tissue Int 56: 403-407.