Human serum inactivates non-glycosylated but not glycosylated granulocyte colony stimulating factor by a protease dependent mechanism: Significance of carbohydrates on the glycosylated molecule

Biologicals

Volumn 32, Issue 1, 2004, Pages 37-47

  Carter, Clive R D ^a   Keeble, James R ^a   Thorpe, Robin ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

2 Macroglobulin; Biological activity; G CSF; Glycosylation; Serum

Indexed keywords

ALPHA 2 MACROGLOBULIN; CARBOHYDRATE; GRANULOCYTE COLONY STIMULATING FACTOR; PROTEINASE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ESCHERICHIA COLI; GENE EXPRESSION; GLYCOSYLATION; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE DEPENDENCE;

ALPHA-MACROGLOBULINS; ANIMALS; BIOLOGICAL ASSAY; CARBOHYDRATES; CHO CELLS; CRICETINAE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GLYCOSYLATION; GRANULOCYTE COLONY-STIMULATING FACTOR; HYDROGEN-ION CONCENTRATION; SERUM; TEMPERATURE; TIME FACTORS;

EID: 1542513235     PISSN: 10451056     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biologicals.2003.12.002     Document Type: Article

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