IL-2 induces T cell adherence to extracellular matrix: Inhibition of adherence and migration by IL-2 peptides generated by leukocyte elastase

Journal of Immunology

Volumn 161, Issue 5, 1998, Pages 2465-2472

  Ariel, Amiram ^a   Yavin, Eran J ^a   Hershkoviz, Rami ^a   Avron, Ann ^a   Franitza, Suzanne ^a   Hardan, Izhar ^b   Cahalon, Liora ^a   Fridkin, Mati ^a   Lider, Ofer ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; FIBRONECTIN; INTERLEUKIN 2; INTERLEUKIN 7; LAMININ; LEUKOCYTE ELASTASE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; PEPTIDE ANALYSIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; T LYMPHOCYTE;

ACTINS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CELL ADHESION; CELL MOVEMENT; CHEMOTAXIS, LEUKOCYTE; COLLAGEN; CYTOSKELETON; EXTRACELLULAR MATRIX; FIBRONECTINS; HUMANS; INFLAMMATION; INTERLEUKIN-2; LAMININ; LEUKOCYTE ELASTASE; LYMPHOCYTE ACTIVATION; MACROPHAGE INFLAMMATORY PROTEIN-1; PEPTIDE FRAGMENTS; T-LYMPHOCYTES;

EID: 0032169211     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
2. Clark, E. A., and J. S. Brugge. 1995. Integrins and signal transduction: the road taken. Science 268:233.
3. Ben-Baruch, A., D. F. Michiel, and J. J. Oppenheim. 1995. Signals and receptors involved in recruitment of inflammatory cells. J. Biol. Chem. 270:11703.
4. Nathan, C., and M. Sporn. 1991. Cytokines in context. J. Cell Biol. 113:981.
5. Blasi, F. 1997. uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways? Immunol. Today 9:415.
6. Gilat, D., L. Cahalon, R. Hershkoviz, and O. Lider. 1996. Counter-interactions between tissue-infiltrating T lymphocytes, pro-inflammatory mediators, and enzymatically modified extracellular matrix. Immunol. Today 17:16.
7. Smith, K. A. 1988. Interleukin-2: inception, impact, and implications. Science 240:875.
8. Taniguchi, T., and Y. Minami. 1993. The IL-2/IL-2 receptor system: a current overview. Cell 73:5.
9. Li, J., S. Gyorffy, S. Lee, and C. S. Kwok. 1996. Effect of recombinant human interleukin-2 on neutrophil adherence to endothelial cells in vitro. Inflammation 20:361.
10. Wilkinson, P. C., and I. Newman. 1994. Chemoattractant activity of IL-2 for human lymphocytes: a requirement for the IL-2 receptor β-chain. Immunology 82:134.
11. Loetscher, P., M. Seitz, M. Baggiolini, and B. Moser. 1996. Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J. Exp. Med. 184:569.
12. Minami, Y., and T. Taniguchi. 1995. IL-2 signaling: recruitment and activation of multiple protein tyrosine kinases by the components of the IL-2 receptor. Curr. Opin. Cell Biol. 7:156.
13. Ju, G., I. Collins, K. L. Kaffka, W. H. Tsien, R. Chizzonite, R. Crowl, R. Bhatt, and P. L. Kilian. 1987. Structure-function analysis of human interleukin-2: identification of amino acid residues required for biological activity. J. Biol. Chem. 262:5723.
14. Kuo, L. M., and R. J. Robb. 1986. Structure-function relationships for the IL 2-receptor system. II. Localization of an IL-2 binding site on high and low affinity receptors. J. Immunol. 137:1538.
15. Packard, B. Z., H. S. Mostowski, and A. Komoriya. 1995. Mitogenic stimulation of human lymphocytes mediated by a cell surface elastase. Biochem. Biophys. Acta 1269:51.
16. Bristow, C. L., L. K. Lyford, D. P. Stevens, and P. M. Flood. 1991. Elastase is a constituent product of T cells. Biochem. Biophys. Res. Commun. 181:232.
17. Doling, G., F. Frank, C. Boudir, S. Herbert, B. Fleischer, and G. Bellon. 1995. Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis. J. Immunol. 154:4842.
18. 2) and modulates polymorphonuclear leukocyte adhesion. J. Exp. Med. 84:1213.
19. Padrines, M., M. Wolf, A. Walz, and M. Baggiolini. 1994. lnterleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3. FEBS Lett. 352:231.
20. + T lymphocytes to intact or heparinase-treated subendothelial extracellular matrix by diffusible or anchored MIP-1β and RANTES. J. Immunol. 153:4899.
21. Ariel, A., R. Hershkoviz, L. Cahalon, C. Chen, D. E. Williams, S. K. Akiyama, K. M. Yamada, R. Alon, T. Lapidot, and O. Lider. 1997. Induction of T cell adhesion to extracellular matrix and endothelial cell ligands by soluble or matrix-bound IL-7. Eur. J. Immunol. 27:2562.
22. Kishimoto, K., T. Taga, and S. Akira. 1994. Cytokine signal transduction. Cell 76:253.
23. Ratner, S., P. Patrick, and G. Bora. 1992. Lymphocyte development of adherence and motility in extracellular matrix during IL-2 stimulation. J. Immunol. 149:681.
24. 1 integrin (CD29) stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components. J. Cell Biol. 116:499.
25. Ben-Baruch, A., M. Grimm, K. Bengali, G. A. Evans, O. Chertov, J. M. Wang, O. M. Howard, N. Mukaid, K. Matsushima, and J. J. Oppenheim. 1997. The differential ability of IL-8 and neutrophil-activating peptide-2 to induce attenuation of chemotaxis is mediated by their divergent capabilities to phosphorylate CXCR2 (IL-8 receptor B). J. Immunol. 158:5927.
26. Yavin, E. J., L. Yan, D. M. Desiderio, and M. Fridkin. 1996. Synthetic peptides derived from the sequence of human C reactive protein inhibit the enzymatic activity of human leukocyte elastase and cathepsin G. Int. J. Pept. Protein Res. 48:465.
27. Baugh, J., and Travis, J. 1976. Human leukocyte granule elastase: rapid isolation and characterization. Biochemistry 15:836.
28. 1 integrins and extracellular matrix components. Int. Immunol. 7:567.
29. Shimizu, Y., and S. W. Hunt III. 1996. Regulating integrin-mediated adhesion: one more function for PI 3-kinase? Immunol. Today 17:565.
30. Sanchez-Mateos, P., C. Cabañas, and F. Sánchez-Madrid. 1996. Regulation of integrin function. Semin. Cancer Biol. 7:99.
31. Newham, P., and M. J. Humphries. 1996. Integrin adhesion receptors: structure, function and implication for biomedicine. Mol. Med. Today 2:304.
32. Miyamoto, S., H. Teramoto, O. A. Coso, J. S. Gutkind, P. D. Burbelo, S. K. Akiyama, and K. M. Yamada. 1995. Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J. Cell Biol. 131:791.
33. Tanaka, Y., D. Adams, and S. Shaw 1993. Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes. Immunol. Today 14:111.
34. Owen, C. A., M. A. Campbell, P. L. Sannes, S. S. Boukedes, and E. J. Campbell. 1995. Cell surface-bound elastase and cathepsin F on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases. J. Cell Biol. 131:775.
35. Csernok, E., M. Ernst, W. Schmitt, D. F. Bainton, and W. L. Gross. 1994. Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo. Clin. Exp. Immunol. 95:244.
36. Plow, E. F., D. E. Freaney, J. Plescia, and L. A. Miles. 1986. The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type. J. Cell Biol. 103:2411.
37. Leppert, D., E. Waubant, R. Galardy, N. W. Bunnett, and S. L. Hauser. 1995. T cell gelatinases mediate basement membrane transemigration in vitro. J. Immunol. 154:4379.
38. Pleass, R., and R. Camp. 1994. Cytokines induce lymphocyte migration in vitro by direct, receptor-specific mechanisms. Eur. J. Immunol. 24:273.
39. Sauve, K., M. Nachman, C. Spence, P. Bailon, E. Campbell, W. H. Tsien, J. A. Kondas, J. Hakimi, and G. Ju. 1991. Localization in human interleukin 2 of the binding site to the α-chain (p55) of the interleukin 2 receptor. Proc. Natl. Acad. Sci. USA 88:4636.
40. 1 integrin subunit in vitro. J. Cell Biol. 111:721.
41. Downey, G. P., C. K. Chan, P. Lea, A. Taiki, and S. Grinstein. 1992. Phorbol ester-induced actin assembly in neutrophils: role of the protein kinase C. J. Cell Biol. 116:695.
42. Gomez, J., A. Garcia, L. R. Borlado, P. Bonay, C. Martinez, A. Silva, M. Fresno, A. C. Carrera, C. Eicher-Streiber, and A. Rebollo. 1997. IL-2 signaling controls actin organization through p-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-ζ. J. Immunol. 158:1516.
43. Hauzenberger, D., J. Klominek, S. E. Bergstrom, and K. G. Sundqvist. 1995. T lymphocyte migration: the influence of interactions via adhesion molecules, the T cell receptor, and cyokines. Crit. Rev. Immunol. 15:285.