Drug-selected co-expression of P-glycoprotein and gp91 in vivo from an MDR1-bicistronic retrovirus vector Ha-MDR-IRES-gp91

Journal of Gene Medicine

Volumn 5, Issue 5, 2003, Pages 366-376

  Sugimoto, Yoshikazu ^a   Tsukahara, Satomi ^a   Sato, Shigeo ^a   Suzuki, Mutsumi ^a   Nunoi, Hiroyuki ^b   Malech, Harry L ^c   Gottesman, Michael M ^d   Tsuruo, Takashi ^a,e  

^a CANCER CHEMOTHERAPY CENTER   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

Bicistronic retrovirus vector; Chronic granulomatous disease; Drug resistance; Gene therapy; Hematopoietic stem cell; P glycoprotein

Indexed keywords

CD34 ANTIGEN; GLYCOPROTEIN GP 91; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; RETROVIRUS VECTOR; VINCRISTINE; ANTINEOPLASTIC AGENT; CYBB PROTEIN, HUMAN; MEMBRANE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CHRONIC GRANULOMATOUS DISEASE; CONTROLLED STUDY; DNA MODIFICATION; EPSTEIN BARR VIRUS; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONSTRUCT; GENETIC TRANSDUCTION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MALE; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL GENE THERAPY; VIRAL GENE DELIVERY SYSTEM; X CHROMOSOME LINKED DISORDER; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CELL SEPARATION; CELL STRAIN 3T3; FLOW CYTOMETRY; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC LINKAGE; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; METHODOLOGY; MOUSE; PHENOTYPE; RETROVIRUS; TIME; TRANSGENE; ULTRASTRUCTURE; X CHROMOSOME;

ANIMALS; ANTIGENS, CD34; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BONE MARROW TRANSPLANTATION; CELL SEPARATION; FLOW CYTOMETRY; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GRANULOMATOUS DISEASE, CHRONIC; HEMATOPOIETIC STEM CELLS; HUMANS; LINKAGE (GENETICS); MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MODELS, GENETIC; NADPH OXIDASE; NIH 3T3 CELLS; P-GLYCOPROTEIN; PACLITAXEL; PHENOTYPE; RETROVIRIDAE; SUPEROXIDES; TIME FACTORS; TRANSGENES; VINCRISTINE; X CHROMOSOME;

EID: 1542466885     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.362     Document Type: Article

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