Bile acids induce cyclooxygenase-2 expression in human pancreatic cancer cell lines

Carcinogenesis

Volumn 25, Issue 3, 2004, Pages 419-423

  Tucker, Olga N ^a,c   Dannenberg, Andrew J ^a,b   Yang, Eun K ^a,b   Fahey III, Thomas J ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b STRANG CANCER PREVENTION CENTER   (United States)

^c MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BILE ACID CONJUGATE; CHENODEOXYCHOLIC ACID; CYCLOOXYGENASE 2; DEOXYCHOLIC ACID; MESSENGER RNA; PROSTAGLANDIN E2; TAUROCHENODEOXYCHOLIC ACID;

ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME MECHANISM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PANCREAS CANCER; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; UPREGULATION; WESTERN BLOTTING;

BILE ACIDS AND SALTS; BLOTTING, WESTERN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; PANCREATIC NEOPLASMS; PHOSPHOLIPASES A; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 1542399119     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh010     Document Type: Article

References (35)

1. Ahlgren,J.D. (1996) Epidemiology and risk factors in pancreatic cancer. Semin. Oncol., 23, 241-250.
2. Wynder,E.L., Mabuchi,K., Maruchi,N. and Fortner,J.G. (1973) Epidemiology of cancer of the pancreas. J. Natl Cancer Inst., 50, 645-667.
3. Binstock,M., Krakow,D., Stamler,J., Reiff,J., Persky,V., Liu,K. and Moss,D. (1983) Coffee and pancreatic cancer: An analysis of international mortality data. Am. J. Epidemiol., 118, 630-640.
4. Ghadirian,P., Simard,A., Baillargeon,J. et al. (1991) Nutritional factors and pancreatic cancer in the francophone community in Montreal, Canada. Int. J. Cancer, 47, 1-6.
5. Reddy,B.S. (1981) Diet and excretion of bile acids. Cancer Res., 41, 3766-3788.
6. Hill,M.J. (1991) Bile acids and colorectal cancer: hypothesis. Eur. J. Cancer Prev., 2, 69-74.
7. Reddy,B.S., Weisburger.J.H. and Wynder,E.L. (1978) Colon cancer: Bile salts as tumor promoters. In Slaga,T.J., Sivak,A. and Boutwell,R.K. (eds), Carcinogensis, Vol. 2. Mechanisms of Tumor Promotion and Carcinogenesis. Raven Press, New York, pp. 1453-1464.
8. Kaibara,N., Yurugi,E. and Koga,S. (1984) Promoting effect of bile acids on the chemical transformation of C3H/10T1/2 fibroblasts in vitro. Cancer Res., 44, 5482-5485.
9. Zhang,F., Subbaramaiah,K., Altorki,N. and Dannenberg,A.J. (1998) Dihydroxy bile acids activate the transcription of cyclooxygenase-2. J. Biol. Chem., 273, 2424-2428.
10. Shirvani,V.N., Ouatu-Lascar,R., Kaur,B.S. et al. (2000) Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure. Gastroenterology, 118, 487-496.
11. Glinghammar,B. and Rafter,J. (2001) Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells. Gastroenterology, 120, 401-410.
12. Herschman,H.R., Reddy,S.T. and Xie,W. (1997) Function and regulation of prostaglandin synthase-2. Adv. Exp. Med. Biol., 407, 61-66.
13. Subbaramaiah,K., Telang,N., Bansal,M.B., Weksler,B.B. and Dannenberg,A.J. (1997) Cyclooxygenase-2 gene expression is upregulated in transformed mammary epithelial cells. Ann. N. Y. Acad. Sci., 833, 179-185.
14. Eberhart,C.E., Coffey,R.J., Radhika,A., Giardiello,F.M., Ferrenbach,S. and Du Bois,R.N. (1994) Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology, 107, 1183-1188.
15. Ristimaki,A., Honkanen,N., Jankala,H., Sipponen,P. and Harkonen,M. (1997) Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res., 57, 1276-1280.
16. Wilson,K.T., Fu,S., Ramanujam,K.S. and Meltzer,S.J. (1998) Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res., 58, 2929-2934.
17. Tucker,O.N., Danneberg,A.J., Tang,E.K. et al. (1999) Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res., 59, 987-990.
18. Oshima,M., Dinchuk,J.E., Kargman,S.L., Oshima,H., Hancock,B., Kwong,E., Trzaskos,J.M., Evans,J.F. and Taketo,M.M. (1996) Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell, 87, 803-809.
19. Kawamori,T., Rao,C.V., Seibert,K. and Reddy,B.S. (1998) Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res., 58, 409-412.
20. Molina,M.A., Sitja-Arnau,M., Lemoine,M.G. et al. (1999) Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs. Cancer Res., 59, 4356-4362.
21. Kokawa,A., Kondo,H., Gotoda,T. et al. (2001) Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by inhibitors. Cancer, 91, 333-338.
22. Birt,D.F., Salmasi,S. and Pour,P.M. (1981) Enhancement of experimental pancreatic cancer in Syrian golden hamsters by dietary fat. J. Natl Cancer Inst., 67, 1327-1332.
23. De Rubertis,F.R. and Craven,P.A. (1987) Relationship of bile salt stimulation of colonic epithelial phospholipid turnover and proliferative activity: Role of activation of protein kinase C1. Prev. Med., 16, 572-579.
24. Takano,S., Akagi,M. and Bryan,G.T. (1984) Stimulation of omithine decarboxylase activity and DNA synthesis by phorbol esters or bile acids in rat colon. Gann, 75, 29-35.
25. Cohen,B.I., Raicht,R.F., Deschner,E.E., Takahashi,M., Sarwal,A.N. and Fazzini,E. (1980) Effect of cholic acid feeding on N-methyl-N-nitrosourea-induced colon tumors and cell kinetics in rats. J. Natl Cancer Inst., 64, 573-578.
26. Magnuson,B.A., Shirtliff,N. and Bird,R.P. (1994) Resistance of aberrant crypt foci to apoptosis induced by azoxymethane in rats chronically fed cholic acid. Carcinogenesis, 15, 1459-1462.
27. Garewal,H., Bernstein,H., Bernstein,C., Sampliner,R. and Payne,C. (1996) Reduced bile acid-induced apoptosis in 'normal' colorectal mucosa: A potential biological marker for cancer risk. Cancer Res., 56, 1480-1483.
28. Mahmoud,N.N., Dannenberg,A.J., Bilinski,R.T., Mestre,J.R., Chadburn,A., Churchill,M., Martucci,C. and Bertagnolli,M.M. (1999) Administration of an unconjugated bile acid increases duodenal tumors in a murine model of familial adenomatous polyposis. Carcinogenesis, 20, 299-303.
29. Hirano,F., Tanada,H., Makino,Y., Okamoto,K., Hiramoto,M., Handa,H. and Makino,I. (1996) Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. Carcinogenesis, 17, 427-433.
30. Pongracz,J., Clark,P., Neoptolemos,J.P. and Lord,J.M. (1995) Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids. Int. J. Cancer, 61, 35-39.
31. Fitzer,C.J., O'Brian,C.J., Guillem,J.G. and Weinstein,I.B. (1987) The regulation of protein kinase C by chenodeoxycholate, deoxycholate and several structurally related bile acids. Carcinogenesis, 8, 217-220.
32. Ming,L., Lotan,R., Levin,B. et al. (2000) Aspirin induction of apoptosis in esophageal cancer: A potential for chemoprevention. Cancer Epidemiol. Biomarkers Prev., 9, 545-549.
33. Zhang,Z., Sheng,H., Shao,J. et al. (2000) Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells. Neoplasia, 2, 523-530.
34. Hofmann,A.F. and Mekhijian,H.S. (1973) Bile acids and the intestinal absorption of fat and electrolytes in health and disease. In: Nair,P.P. and Kritchevsky,D. (eds), The Bile Acids: Chemistry, Physiology and Metabolism. Plenum Press, NY, pp. 103-151.
35. Pinotti,H.W., de Sousa,O.M., Parolari,J.B., Conte,V.P., Raia,A. and Netto,A.C. (1967) The dynamics of the main biliary duct and the mechanism of the biliopancreatic reflux. Am. J. Dig. Dis., 12, 878-890.