Duloxetine versus placebo in the treatment of European and Canadian women with stress urinary incontinence

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 111, Issue 3, 2004, Pages 249-257

  Van Kerrebroeck, Philip ^a   Abrams, Paul ^b   Lange, Rainer ^c   Slack, Mark ^d   Wyndaele, Jean Jacques ^e   Yalcin, Ilker ^f   Bump, Richard C ^f  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

^c DRK Krankenhaus   (Germany)

^d Hinchingbrooke Addenbrooke's H   (United Kingdom)

^e UNIVERSITY OF ANTWERP   (Belgium)

^f ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DULOXETINE;

ADULT; AGED; ALGORITHM; ARTICLE; ATTENTION DEFICIT DISORDER; BLADDER CAPACITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ELECTROCARDIOGRAM; EUROPE; FEMALE; HUMAN; INSOMNIA; LABORATORY TEST; MAJOR CLINICAL STUDY; NAUSEA; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; URINE INCONTINENCE; URODYNAMICS;

EID: 1542374616     PISSN: 14700328     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2004.00067.x     Document Type: Article

References (27)

1. Abrams P, Cardozo L, Fall M, et al. The standardisation of terminology of lower urinary tract function: report from the standardistion subcommittee of the International Continence Society. Neurourol Urodyn 2002;21:167-178.
2. Hampel C, Wienhold D, Benken N, Eggersmann C, Thüroff JW. Definition of overactive bladder and epidemiology of urinary incontinence. Urology 1997;50(S6A):4-14.
3. Hannestad YS, Rortveit G, Sandvik H, Hunskaar S. A community-based epidemiological survey of female urinary incontinence. The Norwegian EPINCONT study. J Clin Epidemiol 2000;53:1150-1157.
4. Brown JS, Waetjen LE, Subak LL, Thome DH, Ven Den Eeden S, Vittinghoff E. Pelvic organ prolapse surgery in the United States, 1997. Am J Obstet Gynecol 2002;186:712-716.
5. Lagro-Janssen T, Van Weel C. Long-term effect of treatment of female incontinence in general practice. Br J Gen Pract 1998;48:1735-1738.
6. Wilson PD, Bø K, Hay-Smith J, et al. Conservative management in women. In: Abrams P, Khoury S, Wein A, editors. Incontinence. Plymouth, UK: Health Publication, 2002:573-624.
7. Espey MJ, Du H-J, Downie JW. Serotonergic modulation of spinal ascending activity and sacral reflex activity evoked by pelvic nerve stimulation in cats. Brain Res 1998;798:101-108.
8. Thor KB, Hisamitsu T, de Groat WC. Unmasking of a neonatal somatovesical reflex in adult cats by the serotonin autoreceptor agonist 5-methoxy-N,N- dimethyltryptamine. Brain Res Dev Brain Res 1990; 54:35-425.
9. Danuser H, Thor KB. Spinal 5-HT2 receptor-mediated facilitation of pudendal nerve reflexes in the anaesthetized cat. Br J Pharmacol 1996;118:150-154.
10. Krier J, Thor KB, de Groat WC. Effects of clonidine on the lumbar sympathetic pathways to the large intestine and urinary bladder of the cat. Eur J Pharmacol 1979;59:47-53.
11. Pedersen E, Torring J, Klemar B. Effect of the alpha-adrenergic blocking agent thymoxamine on the neurogenic bladder and urethra. Acta Neurol Scand 1980;61:107-114.
12. Gajewski J, Downie JW, Awad SA. Experimental evidence for a central nervous system site of action in the effect of alpha-adrenergic blockers on the external urinary sphincter. J Urol 1984;132:403-409.
13. Downie JW, Bialik GJ. Evidence for a spinal site of action of clonidine on somatic and viscerosomatic reflex activity evoked on the pudendal nerve in cats. J Pharmacol Exp Ther 1988;246:352-358.
14. Downie JW, Espey MJ, Gajewski JB. Alpha 2-adrenoceptors not imidazole receptors mediate depression of a sacral spinal reflex in the cat. Eur J Pharmacol 1991;195:301-304.
15. Espey MJ, Downie JW, Fine A. Effect of 5-HT receptor and adrenoceptor antagonists on micturition in conscious cats. Eur J Pharmacol 1992;221:167-170.
16. Bymaster FP, Dreshfield-Ahmad LJ, Threlkeld PG, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology 2001;25:871-880.
17. Thor KB, Katofiasc MA. Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor, on central neural control of lower urinary tract function in the chloralose-anesthetized female cat. J Pharmacol Exp Ther 1995;274:1014-1024.
18. Katofiasc MA, Nissen J, Audia JE, Thor KB. Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats. Life Sci 2002;71:1227-1236.
19. Norton PA, Zinner NR, Yalcin I, Bump RC. Duloxetine versus placebo in the treatment of stress urinary incontinence. Am J Obstet Gynecol 2002;187:40-48.
20. Wagner TH, Patrick DL, Bavendam TG, Martin ML, Buesching DP. Quality of life of persons with urinary incontinence: development of a new measure. Urology 1996;47:67-71.
21. Patrick DL, Martin ML, Bushnell DM, Yalcin I, Wagner TH, Buesching DP. Quality of life of women with urinary incontinence: further development of the incontinence quality of life instrument (I-QOL). Urology 1999;53:71-76.
22. Donovan JL, Badia X, Corcos J, et al. Symptom and quality of life assessment. In: Abrams P, Cardozo L, Khoury S, Wein A, editors. Incontinence, 2nd edition. Plymouth, UK: Health Publication, 2002: 267-316.
23. Yalcin I, Bump RC. Validation of two global impression questionnaires for incontinence. Am J Obstet Gynecol 2003;189:98-101.
24. van Elteren PH. On the combination of independent two-sample tests of Wilcoxon. Bull Int Stat Inst 1960;37:1-13.
25. Zinner NR, Dmochowski RR, Norton PA, Miklos JR, Yalcin I, Bump RC. Duloxetine versus placebo in the treatment of North American women with stress urinary incontinence. J Urol 2003; 170:1259-1263.
26. Millard RJ, Moore K, Rencken R, Yalcin I, Bump RC for the Duloxetine UI Study Group. Duloxetine versus placebo in the treatment of stress urinary incontinence: a four continent randomized clinical trial. Br J Urol Int. In press.
27. Andersson K-E, Appell R, Awad S, et al. Pharmacological treatment of urinary incontinence. In: Abrams P, Khoury S, Wein A, editors. Incontinence. Plymouth, UK: Health Publication, 2002:481-511.