Synthesis of Novel Basic Head-to-Side-Chain Cyclic Dynorphin A Analogs: Strategies and Side Reactions

Biopolymers - Peptide Science Section

Volumn 71, Issue 6, 2003, Pages 620-637

  Vig, Balvinder S ^a,d   Murray, Thomas F ^b   Aldrich, Jane V ^c  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

opioid receptors; Dynorphin A analogs; Head to side chain cyclic peptides; N terminal alkylation; Opioid peptides; Synthetic methodology

Indexed keywords

ALKYLATION; CONFORMATIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SYNTHESIS (CHEMICAL);

CYCLIC PEPTIDES; NEUTRALIZATION;

BIOPOLYMERS;

9 FLUORENYLMETHYL CHLOROFORMATE; ACETIC ACID DERIVATIVE; BROMOACETIC ACID; CYCLOPEPTIDE; DIPRENORPHINE; DYNORPHIN A DERIVATIVE; KAPPA OPIATE RECEPTOR; LYSINE; OPIATE PEPTIDE; OPIATE RECEPTOR;

ALKYLATION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; CONFERENCE PAPER; DEPROTECTION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; PROTEIN CONFORMATION; STRUCTURE ANALYSIS;

ANIMALS; CHO CELLS; CRICETINAE; DYNORPHINS; PEPTIDES, CYCLIC; RECEPTORS, OPIOID;

EID: 1542374136     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.10591     Document Type: Conference Paper

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