Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphin A(1-11)-NH21

Journal of Medicinal Chemistry

Volumn 39, Issue 5, 1996, Pages 1136-1141

  Lung, Feng Di T ^a   Collins, Nathan ^a   Stropova, Dagmar ^b   Davis, Peg ^b   Yamamura, Henry I ^b   Porreca, Frank ^b   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNORPHIN A DERIVATIVE; KAPPA OPIATE RECEPTOR; OPIATE AGONIST;

ANIMAL TISSUE; ARTICLE; BINDING KINETICS; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; PAIN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CELL MEMBRANE; CYCLIZATION; DRUG DESIGN; DYNORPHINS; GUINEA PIGS; ILEUM; LACTAMS; MALE; MOLECULAR SEQUENCE DATA; MUSCLE CONTRACTION; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, OPIOID, KAPPA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029933436     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950369c     Document Type: Article

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