Valency of antibody binding to virions and its determination by surface plasmon resonance

Reviews in Medical Virology

Volumn 14, Issue 2, 2004, Pages 123-135

  Dimmock, Nigel J ^a   Hardy, Sam A ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; MEMBRANE PROTEIN;

ANTIGEN BINDING; BINDING AFFINITY; CROSS LINKING; INFECTION; NONHUMAN; REVIEW; SURFACE PLASMON RESONANCE; VIRION; VIRUS ENVELOPE; VIRUS NEUTRALIZATION; VIRUS PARTICLE;

ANTIBODIES, VIRAL; ANTIBODY AFFINITY; BINDING SITES, ANTIBODY; IMMUNOGLOBULIN G; INFLUENZA A VIRUS; SURFACE PLASMON RESONANCE; VIRION;

EID: 1542374062     PISSN: 10529276     EISSN: None     Source Type: Journal    
DOI: 10.1002/rmv.419     Document Type: Review

References (84)

1. Svehag SE. Formation and dissociation of virus-antibody complexes with special reference to the neutralization process. Prog Med Virol 1968; 10: 1-63.
2. Dimmock NJ. Neutralization of animal viruses. Curr Topics Microbiol Immunol 1993; 183: 1-149.
3. Mosser AG, Leippe D, Rueckert RR. Neutralization of picornaviruses: support for the pentamer bridging hypothesis. In Molecular Aspects of Picornavirus Infection and Detection, Semler BL, Ehrenfeld E (eds). American Society for Microbiology: Washington, 1989; 155-167.
4. Thomas AAM, Vrijsen R, Boeyé A. Relationship between poliovirus neutralization and aggregation. J Virol 1986; 59: 479-485.
5. Wetz K, Willingmann P, Zeichhardt H, et al. Neutralization of poliovirus by polyclonal antibodies requires binding of a single molecule per virion. Arch Virol 1986; 91: 207-220.
6. Taniguchi K, Urasawa S. Different virus-precipitating activities of neutralizing monoclonal antibodies that recognise distinct sites on poliovirus particles. Arch Virol 1987; 92: 27-40.
7. Thomas ADM, Brioen P, Boeyé A. A monoclonal antibody that neutralizes poliovirus by crosslinking virions. J Virol 1985; 54: 7-13.
8. Icenogle JC, Shiwen H, Duke G, et al. Neutralization of poliovirus by a monoclonal antibody: kinetics and stoichiometry. Virology 1983; 127: 412-425.
9. Leippe DM. Stoichiometry of picornavirus neutralization by murine monoclonal antibodies. Doctoral dissertation. University of Wisconsin-Madison, 1991.
10. Almeida J, Cinader B, Howatson A. The structure of antigen-antibody complexes. J Exp Med 1963; 118: 327-340.
11. Lafferty KJ, Oertelis S. The interaction between virus and antibody. III. Examination of virus-antibody complexes with the electron microscope. Virology 1963; 21: 91-99.
12. Svehag S-E, Bloth B. Examination of virus-gammaM antibody complexes by electron microscopy. I. Configuration of gammaM antibodies and mode of attachment of antigen. Virology 1967; 31: 676-687.
13. Kendal AP, Madeley CR. Flocculation of influenza virus by specific anti-neuraminidase antibody. Arch ges Virusforsch 1970; 31: 219-229.
14. Desselberger U (ed.). Medical Virology: A Practical Approach. OUP: Oxford, 1995.
15. Stephenson JR, Warnes A (eds). Diagnostic Virology Protocols. Humana Press: Totowa, 1998.
16. Hazelton PR, Gelderblom HR. Electron microscopy for rapid diagnosis of infectious agents in emergent situations. Emerg Infect Dis 2003; 9: 294-303.
17. Smith TJ. Antibody interactions with rhinovirus: lessons for mechanism of neutralization and the role of immunity in viral evolution. Curr Topics Microbiol Immunol 2001; 260: 1-28.
18. Hewat EA, Blaas D. Structural studies on antibody interacting with viruses. Curr Topics Microbiol Immunol 2001; 260: 29-44.
19. Smith TJ, Olson NH, Cheng RH, et al. Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody. J Virol 1993; 67: 1148-1158.
20. Smith TJ, Olson NH, Cheng RH, et al. Structure of a human rhinovirus-bivalently bound antibody complex: implications for viral neutralization and antibody flexibility. Proc Natl Acad Sci USA 1993; 90: 7015-7018.
21. Hewat EA, Blaas D. Structure of a neutralizing antibody bound bivalently to human rhinovirus 2. EMBO J 1996; 15: 1515-1523.
22. Che Z, Olson NH, Leippe D, et al. Antibody-mediated neutralization of human rhinovirus 14 explored by means of cryoelectron microscopy and x-ray crystallography of virus-Fab complexes. J Virol 1998; 72: 4610-4622.
23. Thouvenin E, Laurent S, Medelaine M-F, et al. Bivalent binding of a neutralizing antibody to a calicivirus involves the torsional flexibility of the antibody hinge. J Mol Biol 1997; 270: 238-246.
24. Booy FP, Roden RBS, Greenstone HL, et al. Two antibodies that neutralize papillomaviruses by different mechanisms show distinct binding patterns at 13 Å resolution. J Mol Biol 1998; 281: 95-106.
25. Porta C, Wang G, Cheng H, et al. Direct imaging of interactions between an icosahedral virus and conjugate fragments by cryoelectron microscopy and x-ray crystallography. Virology 1994; 204: 777-778.
26. Wikoff WR, Wang GJ, Parrish CR, et al. The structure of a neutralized virus: canine parvovirus complexed with neutralizing antibody fragment. Structure 1994; 2: 595-607.
27. Hewat EA, Verdaguer N, Fita I, et al. Structure of the complex of a Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop. EMBO J 1997; 16: 1492-1500.
28. Hewat EA, Marlovits TC, Blaas D. Structure of a neutralizing antibody bound monovalently to human rhinovirus. J Virol 1998; 72: 4396-4402.
29. Verdaguer N, Schoehn G, Ochoa WF, et al. Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralizing antibody: structure and neutralisation. Virology 1999; 255: 260-268.
30. Tormo J, Centeno NB, Fontana E, et al. Docking of a human rhinovirus neutralizing antibody onto the viral capsid. Proteins: Struct Funct Genet 1995; 23: 491-501.
31. Hardy SA, Dimmock NJ. Valency of antibody binding to enveloped virus particles as determined by surface plasmon resonance. J Virol 2003; 77: 1649-1652.
32. Markey F. What is SPR anyway? BIA J 1999; 5: 14-17.
33. Edwards MJ, Dimmock NJ. Two influenza A virus haemagglutinin-specific Fabs neutralize by inhibiting virus attachment to target cells, while neutralization by their IgGs is complex and occurs through fusion-inhibition and attachment-inhibition simultaneously. Virology 2000; 278: 423-435.
34. Edwards MJ, Dimmock NJ. Hemagglutinin 1-specific immunoglobulin G and FAb molecules mediate postattachment neutralization of influenza A virus by inhibition of an early fusion event. J Virol 2001; 75: 10208-10218.
35. 14C]biotin for kinetic studies and for assay. Biochem J 1963; 89: 585-591.
36. Bullough PA, Hughson FM, Skehel JJ, et al. Structure of influenza haemagglutinin at the pH of membrane fusion. Nature (Lond) 1994; 371: 37-43.
37. Junghans RP. Cruel antibody fictions! Cellular antigen enumeration by 'saturation' binding. Immunol Today 1999; 20: 401-406.
38. Nezlin R. Internal movements in immunoglobulin molecules. Adv Immunol 1990; 48: 1-40.
39. Burton DR, Woof JM. Human antibody effector function. Adv Immunol 1992; 51: 1-84.
40. Dubs M-C, Altschuh D, van Regenmortel MHV. Interaction between virus and monoclonal antibodies studied by surface plasmon resonance. Immunol Lett 1991; 31: 59-64.
41. Tosser G, Delaunay T, Kohli E, et al. Topology of bovine rotavirus RF strain VP6 epitopes by real-time biospecific interaction analysis. Virology 1994; 204: 8-16.
42. Casasnovas JM, Springer TA. Kinetics and thermodynamics of virus binding to receptor. J Biol Chem 1995; 270: 13216-13224.
43. Kangtrong SS-H, Briand J-P, Sako N. A single amino acid substitution at N-terminal region of coat protein of turnip mosaic virus alters antigenicity and aphid transmissibility. Arch Virol 1995; 140: 453-467.
44. Xing L, Tjanlund K, Linqvist B, et al. Distinct cellular receptor interactions in poliovirus and rhinoviruses. EMBO J 2000; 19: 1207-1216.
45. Caton AJ, Brownlee GG, Yewdell JW, et al. The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype). Cell 1982; 31: 417-427.
46. Harris LJ, Larson SB, Hasel KW, et al. Refined structure of an intact IgG2a monoclonal antibody. Biochemistry 1997; 36: 1581-1597.
47. Wrigley NG, Laver WG, Downie JC. Binding of antibodies to isolated haemagglutinin and neuraminidase molecules of influenza virus observed in the electron microscope. J Mol Biol 1977; 109: 405-421.
48. Wrigley NG, Brown EB, Daniels RS, et al. Electron microscopy of influenza haemagglutinin-monoclonal antibody complexes. Virology 1983; 131: 308-314.
49. Cusack S, Ruigrok RWH, Krygsman PC, et al. Structure and composition of influenza virus, a small angle neutron scattering study. J Mol Biol 1985; 186: 565-582.
50. Taylor HP, Armstrong SJ, Dimmock NJ. Quantitative relationships between an influenza virus and neutralizing antibody. Virology 1987; 159: 288-298.
51. Enami M, Enami K. Influenza virus hemagglutinin and neuraminidase glycoproteins stimulate the membrane association of the matrix protein. J Virol 1996; 70: 6653-6657.
52. Zhang J, Pekosz A, Lamb RA. Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins. J Virol 2000; 74: 4634-4644.
53. Ali A, Avalos RT, Ponimaskin E, et al. Influenza virus assembly: effect of influenza virus glycoproteins on the membrane-association of M1 protein. J Virol 2000; 74: 8709-8719.
54. Barman S, Ali A, Hui EK-W, et al. Transport of viral proteins to the apical membranes and interaction of matrix protein with glycoproteins in the assembly of influenza viruses. Virus Res 2001; 77: 61-69.
55. Edwards MJ, Dimmock NJ. A haemagglutinin (HA1)-specific FAb neutralizes influenza A virus by inhibiting fusion of virus to target cells. J Gen Virol 2001; 82: 1387-1395.
56. Gelderblom HR, Hausmann EHS, Özel M, et al. Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology 1987; 156: 171-176.
57. Moore JP, McKeating JA, Norton WA, et al. Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4. J Virol 1991; 65: 1133-1140.
58. Moore JP, Klasse PJ. Thermodynamic and kinetic analysis of sCD4 binding to HIV-1 virions and gp120 dissociation. AIDS Res Hum Retroviruses 1992; 8: 443-450.
59. Vrijsen R, Mosser A, Boeyé A. Postadsorption neutralization of poliovirus. J Virol 1993; 67: 3126-3133.
60. Wetz K. Attachment of neutralizing antibodies stabilizes the capsid of poliovirus against uncoating. Virology 1993; 192: 465-472.
61. Wohlfart C. Neutralization of adenoviruses: kinetics, stoichiometry and mechanisms. J Virol 1988; 62: 2321-2328.
62. Varga MJ, Bergman T, Everitt E. Antibodies with specificities against a dispase-produced 15-kilodalton hexon fragment neutralize adenovirus infectivity. J Virol 1990; 64: 4217-4225.
63. Keller R. Studies on the mechanism of enzymatic reactivation of antibody-neutralized poliovirus. J Immunol 1968; 100: 1071-1079.
64. Emini EA, Ostapchuk P, Wimmer E. Bivalent attachment of antibody onto poliovirus leads to conformational alteration and neutralization. J Virol 1983; 48: 547-550.
65. Ruggeri FM, Greenberg HB. Antibodies to the trypsin cleavage peptide VP8* neutralize rotavirus by inhibiting binding of virions to target cells in culture. J Virol 1991; 65: 2211-2219.
66. Ludert JE, Ruiz MC, Higalgo C, et al. Antibodies to rotavirus outer capsid glycoprotein VP7 neutralize infectivity by inhibiting virion decapsidation. J Virol 2002; 76: 6643-6651.
67. Martin S, Casasnovas JM, Staunton DE, et al. Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/immunoglobulin molecules. J Virol 1993; 67: 3561-3568.
68. Kingsford L, Boucquey KH, Cardoso TP. Effects of specific monoclonal antibodies on La Crosse virus neutralization: aggregation, inactivation by Fab fragments, and inhibition of attachment to baby hamster kidney cells. Virology 1991; 180: 591-601.
69. Stewart PL, Chiu CY, Huang S, et al. Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization. EMBO J 1997; 16: 1189-1198.
70. Lafferty KJ. The interaction between virus and antibody. II Mechanism of the reaction. Virology 1963; 21: 76-90.
71. Kida H, Yoden S, Kuwabara M, et al. Interference with a conformational change in the HA molecule of influenza virus by antibodies as a possible neutralization mechanism. Vaccine 1985; 3: 219-222.
72. Yoden S, Kida H, Yanagawa R. Is bivalent binding of monoclonal antibodies to different antigenic areas on the hemagglutinin of influenza virus required for neutralization of viral infectivity? Arch Virol 1985; 85: 209-216.
73. Mathews JH, Roehrig JT, Trent DW. Role of complement and the Fc portion of immunoglobulin G in immunity to Venezuelan equine encephalomyelitis virus infection with glycoprotein-specific monoclonal antibodies. J Virol 1985; 55: 594-600.
74. Colonno RJ, Callahan PL, Leippe DM, et al. Inhibition of rhinovirus attachment by neutralizing monoclonal antibodies and their Fab fragments. J Virol 1989; 63: 36-42.
75. Cavacini LA, Emes CL, Power J, et al. Effect of antibody valency on interaction with cell-surface expressed HIV-1 and viral neutralization. J Immunol 1994; 152: 2538-2545.
76. Schofield DJ, Stephenson JR, Dimmock NJ. Variations in the neutralizing and haemagglutination-inhibiting activities of five influenza A virus-specific IgGs and their antibody fragments. J Gen Virol 1997; 78: 2431-2439.
77. McInerney TL, McLain L, Armstrong SJ, et al. A human IgG1 (b12) specific for the CD4 binding site of HIV-1 neutralizes by inhibiting the virus fusion entry process, but b12 Fab neutralizes by inhibiting a post-fusion event. Virology 1997; 233: 313-326.
78. Lantto J, Fletcher JM, Ohlin M. A divalent antibody format is required for neutralization of human cytomegalovirus via antigenic domain 2 on glycoprotein B. J Gen Virol 2002; 83: 2001-2005.
79. Drew PD, Moss MT, Pasieka TJ, et al. Multimeric humanized varicella-zoster virus antibody fragments to gH neutralize virus while monomeric fragments do not. J Gen Virol 2001; 82: 1959-1963.
80. Carter P. Bispecific human IgG by design. J Immunol Methods 2001; 248: 7-15.
81. Parren PWHI, Mondor I, Naniche D, et al. Neutralization of human immunodeficiency virus type 1 by antibody to gpl20 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity. J Virol 1998; 72: 3512-3519.
82. Boere WAM, Harmsen T, Vinjé J, et al. Identification of distinct antigenic determinants on Semliki Forest virus by using monoclonal antibodies with different antiviral activities. J Virol 1984; 52: 575-582.
83. Schofield DJ, Stephenson JR, Dimmock NJ. High and low efficiency neutralization epitopes on the haemagglutinin of type A influenza virus. J Gen Virol 1997; 78: 2441-2446.
84. Staudt LM, Gerhard W. Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. I Significant variation in repertoire expression between individual mice. J Exp Med 1983; 157: 687-704.