Structure of a neutralizing antibody bound monovalently to human rhinovirus 2

Journal of Virology

Volumn 72, Issue 5, 1998, Pages 4396-4402

  Hewat, Elizabeth A ^a   Marlovits, Thomas C ^b   Blaas, Dieter ^b  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

ANTIGEN BINDING; ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; HUMAN RHINOVIRUS; NONHUMAN; PRIORITY JOURNAL; VIRUS CAPSID;

EID: 0031967887     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.5.4396-4402.1998     Document Type: Article

References (39)

1. Appleyard, G., S. M. Russell, B. E. Clarke, S. A. Speller, M. Trowbridge, and J. Vadolas. 1990. Neutralisation epitopes on human rhinovirus type 2. J. Gen. Virol. 71:1275-1282.
2. Baker, T. S., and R. H. Cheng. 1996. A model based approach for determining orientations of biological macromolecules imaged by cryoelectron microscopy. J. Struct. Biol. 116:120-130.
3. Brioen, P., D. Dekegel, and A. Boeyé. 1983. Neutralization of poliovirus by antibody-mediated polymerization. Virology 127:463-468.
4. Brioen, P., A. A. Thomas, and A. Boeyé. 1985. Lack of quantitative correlation between the neutralization of poliovirus and the antibody-mediated pI shift of the virions. J. Gen. Virol. 66:609-613.
5. Crowther, R. A. 1971. Procedures for three-dimensional reconstruction of spherical viruses by Fourier synthesis from electron micrographs. Philos. Trans. R. Soc. Lond. Ser. B 261:221-230.
6. Dimmock, N. J. 1993. Neutralisation of animal viruses, p. 88-97. Springer-Verlag, Berlin, Germany.
7. Duechler, M., S. Ketter, T. Skern, E. Kuechler, and D. Blaas. 1993. Rhinoviral receptor discrimination: the canyon regions of HRV14 and HRV2 have different sensitivities to mutational change. J. Gen. Virol. 74:2287-2291.
8. Emini, E. A., P. Ostapchuk, and E. Wimmer. 1983. Bivalent attachment of antibody onto poliovirus leads to conformational alteration and neutralization. J. Virol. 48:547-550.
9. Fuller, S. D. 1987. The T=4 envelope of sindbis virus is organised by complementary interactions with a T=3 icosahedral capsid. Cell 48:923-934.
10. Fuller, S. D., S. J. Butcher, R. H. Cheng, and T. S. Baker. 1996. Three-dimensional reconstruction of icosahedral particles. The uncommon line. J. Struct. Biol. 116:48-55.
11. Greve, J. M., G. Davis, A. Meyer, C. P. Forte, S. C. Yost, C. W. Marlor, M. E. Kamarck, and A. McClelland. 1989. The major human rhinovirus receptor is ICAM-1. Cell 56:839-847.
12. Hadfield, A. T., W. Lee, R. Zhao, M. A. Oliveira, L. Minor, R. R. Rueckert, and M. G. Rossmann. 1997. The refined structure of human rhinovirus 16 at 2.15 Å resolution: implications for the viral life cycle. Structure 5:427-441.
13. Hewat, E. A., and D. Blaas. 1996. Structure of a neutralizing antibody bound bivalently to human rhinovirus 2. EMBO J. 15:1515-1523.
14. Hewat, E. A., N. Verdaguer, I. Fita, W. Blakemore, S. Brooks, A. King, J. Newman, E. Domingo, M. G. Mateu, and D. I. Stuart. 1997. Structure of the complex of an Fab fragment of a neutralising antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop. EMBO J. 16: 1492-1500.
15. Hofer, F., M. Gruenberger, H. Kowalski, H. Machat, M. Huettinger, E. Kuechler, and D. Blaas. 1994. Members of the tow density lipoprotein receptor family mediate cell entry of minor group common cold virus. Proc. Natl. Acad. Sci. USA 91:1839-1842.
16. Kim, S., T. J. Smith, M. S. Chapman, M. G. Rossmann, D. C. Pevear, F. J. Dutko, P. J. Felock, G. D. Diana, and M. A. McKinlay. 1989. Crystal structure of human rhinovirus serotype 1A (HRV1A). J. Mol. Biol. 210:91-111.
17. Liu, H., T. J. Smith, W. M. Lee, A. G. Mosser, R. R. Rueckert, N. H. Olson, R. H. Cheng, and T. S. Baker. 1994. Structure determination of a Fab fragment that neutralises human rhinovirus 14 and analysis of the Fab-virus complex. J. Mol. Biol. 240:127-137.
18. Mateu, M. G. 1995. Antibody recognition of picornaviruses and escape from neutralization: a structural view. Virus Res. 38:1-24.
19. McCullough, K. C., F. De Simone, E. Brochi, L. Capucci, J. R. Crowther, and U. Kihm. 1992. Protective immune response against foot-and-mouth disease. J. Virol. 66:1835-1840.
20. Mosser, A. G., D. M. Leippe, and R. R. Rueckert. 1989. Neutralization of picornaviruses: support for the pentamer bridging hypothesis, p. 155-167. In B. L. Semler and E. Ehrenfeld (ed.), Molecular aspects of picornavirus infection and detection. American Society for Microbiology, Washington, D.C.
21. Oliveira, M. A., R. Zhao, W. M. Lee, M. J. Kremer, L. Minor, R. R. Rueckert, G. D. Diana, D. C. Pevear, F. J. Dutko, M. A. McKinlay, and M. G. Rossmann. 1993. The structure of human rhinovirus 16. Structure 1:51-68.
22. Peitsch, M. C. 1995. Protein modelling by e-mail. Bio/Technology 13:658-660.
23. Peitsch, M. C. 1996. ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling. Biochem. Soc. Trans. 24:274-279.
24. Porta, C., G. Wang, H. Cheng, Z. Chen, T. S. Baker, and J. E. Johnson. 1994. Direct imaging of interactions between an icosahedral virus and conjugate Fab fragments by cryo-electron microscopy and X-ray crystallography. Virology 204:777-788.
25. Rossmann, M. G., E. Arnold, J. W. Erickson, E. A. Frankenberger, J. P. Griffith, H. J. Hecht, J. E. Johnson, G. Kamer, M. Luo, A. G. Mosser, R. R. Rueckert, B. Sherry, and G. Vriend. 1985. Structure of a common cold virus and functional relationship to other picornaviruses. Nature 317:145-153.
26. Rueckert, R. R. 1996. Picornaviridae, p. 609-654. In B. N. Fields and D. M. Knipe (ed.), Virology. Raven Press, New York, N.Y.
27. Russell, S. Unpublished data.
28. Schoehn, G., P. Fender, J. Chroboczek, and E. A. Hewat. 1996. Adenovirus 3 penton dodecahedron exhibits structural changes of the base on fibre binding. EMBO J. 15:6841-6846.
29. Sherry, B., A. G. Mosser, J. R. Colonno, and R. R. Rueckert. 1986. Use of monoclonal antibodies to identify four neutralization immunogens on a common cold picornavirus, human rhinovirus. J. Virol. 57:246-257.
30. Skern, T., W. Sommergruber, D. Blaas, C. Pieler, and E. Kuechler. 1984. Relationship of human rhinovirus strain 2 and poliovirus as indicated by comparison of the polymerase gene regions. Virology 136:125-132.
31. Smith, T. J., N. H. Olson, R. H. Cheng, H. Liu, E. S. Chase, W. M. Lee, D. M. Leippe, A. G. Mosser, R. R. Rueckert, and T. S. Baker. 1993. Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody. J. Virol. 67:1148-1158.
32. Smith, T. J., N. H. Olson, R. H. Cheng, E. S. Chase, and T. S. Baker. 1993. Structure of a human rhinovirus-bivalently bound antibody complex: implications for viral neutralization and antibody flexibility. Proc. Natl. Acad. Sci. USA 90:7015-7018.
33. Smith, T. J., E. S. Chase, T. J. Schmidt, N. H. Olson, and T. S. Baker. 1996. Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon. Nature 383:350-354.
34. Smith, T. J. (Purdue University). 1997. Personal communication.
35. Thouvenin, E., S. Laurent, M.-F. Madelaine, D. Rasschaert, J.-F. Vautherot, and E. A. Hewat. 1997. Bivalent binding of a neutralising antibody to a calicivirus involves the torsional flexibility of the antibody hinge. J. Mol. Biol. 270:238-246.
36. Tormo, J., D. Blaas, N. R. Parry, D. Rowlands, D. I. Stuart, and I. Fita. 1994. Crystal structure of a human rhinovirus neutralizing antibody complexed with a peptide derived from viral capsid protein VP2. EMBO J. 13:2247-2256.
37. Verdaguer, N., M. G. Mateu, D. Andreu, E. Giralt, E. Domingo, and I. Fita. 1995. Structure of the major antigenic loop of foot-and-mouth disease virus complexed to anti-virus neutralizing antibody. Direct involvement of Arg-Gly-Asp in the interaction. EMBO J. 14:1690-1696.
38. Wein, M. W., D. J. Filman, E. A. Stura, S. Guillot, F. Delpeyroux, R. Crainic, and J. M. Hogle. 1995. Structure of the complex between the Fab fragment of a neutralizing antibody for poliovirus type 1 and its viral epitope. Nat. Struct. Biol. 2:232-243.
39. Zhao, R., D. C. Pevear, M. J. Kremer, V. L. Giranda, J. A. Kofron, J. A. Kuhn, and M. G. Rossmann. 1996. Human rhinovirus 3 at 3.0 Å resolution. Structure 4:1205-1220.