메뉴 건너뛰기




Volumn 15, Issue 3, 2004, Pages 1077-1088

A Novel Role of Nectins in Inhibition of the E-Cadherin-induced Activation of Rac and Formation of Cell-Cell Adherens Junctions

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; CELL ADHESION MOLECULE; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN; NECTIN; PROTEIN CDC42; RAC PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 1542373716     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E03-05-0321     Document Type: Article
Times cited : (40)

References (43)
  • 1
    • 0037423380 scopus 로고    scopus 로고
    • ADIP: A novel afadin- and α-actinin-binding protein localized at cell-cell adherens junctions
    • Asada, M., Irie, K., Morimoto, K., Yamada, A., Ikeda, W., Takeuchi, M., and Takai, Y. (2003). ADIP: a novel afadin- and α-actinin-binding protein localized at cell-cell adherens junctions. J. Biol. Chem. 278, 4103-4111.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4103-4111
    • Asada, M.1    Irie, K.2    Morimoto, K.3    Yamada, A.4    Ikeda, W.5    Takeuchi, M.6    Takai, Y.7
  • 2
    • 0037020084 scopus 로고    scopus 로고
    • Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor
    • Betson, M., Lozano, E., Zhang, J., and Braga, V.M.M. (2002). Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor. J. Biol. Chem. 277, 36962-36969.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36962-36969
    • Betson, M.1    Lozano, E.2    Zhang, J.3    Braga, V.M.M.4
  • 3
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga, V.M., Machesky, L.M., Hall, A., and Hotchin, N.A. (1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J. Cell Biol. 137, 1421-1431.
    • (1997) J. Cell Biol. , vol.137 , pp. 1421-1431
    • Braga, V.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4
  • 4
    • 0036696823 scopus 로고    scopus 로고
    • Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion
    • Ehrlich, J.S., Hansen, M.D.H., and Nelson, W.J. (2002). Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion. Dev. Cell 3, 259-270.
    • (2002) Dev. Cell , vol.3 , pp. 259-270
    • Ehrlich, J.S.1    Hansen, M.D.H.2    Nelson, W.J.3
  • 5
    • 0037206934 scopus 로고    scopus 로고
    • Involvement of nectin in the localization of junctional adhesion molecule at tight junctions
    • Fukuhara, A. et al. (2002a). Involvement of nectin in the localization of junctional adhesion molecule at tight junctions. Oncogene 21, 7649-7655.
    • (2002) Oncogene , vol.21 , pp. 7649-7655
    • Fukuhara, A.1
  • 7
    • 0030056968 scopus 로고    scopus 로고
    • Cell adhesion: The molecular basis of tissue architecture and morphogenesis
    • Gumbiner, B.M. (1996). Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357.
    • (1996) Cell , vol.84 , pp. 345-357
    • Gumbiner, B.M.1
  • 8
    • 0038054266 scopus 로고    scopus 로고
    • Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions
    • Honda, T., Shimizu, K., Fukuhara, A., Irie, K., and Takai, Y. (2003a). Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions. Biochem. Biophys. Res. Commun. 306, 104-109.
    • (2003) Biochem. Biophys. Res. Commun. , vol.306 , pp. 104-109
    • Honda, T.1    Shimizu, K.2    Fukuhara, A.3    Irie, K.4    Takai, Y.5
  • 9
    • 0037689074 scopus 로고    scopus 로고
    • Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts
    • Honda, T., Shimizu, K., Kawakatsu, T., Fukuhara, A., Irie, K., Nakamura, T., Matsuda, M., and Takai, Y. (2003b). Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts. Genes Cells 8, 481-491.
    • (2003) Genes Cells , vol.8 , pp. 481-491
    • Honda, T.1    Shimizu, K.2    Kawakatsu, T.3    Fukuhara, A.4    Irie, K.5    Nakamura, T.6    Matsuda, M.7    Takai, Y.8
  • 10
    • 0037273456 scopus 로고    scopus 로고
    • Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion
    • Honda, T. et al. (2003c). Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion. Genes Cells 8, 51-63.
    • (2003) Genes Cells , vol.8 , pp. 51-63
    • Honda, T.1
  • 11
    • 0036724188 scopus 로고    scopus 로고
    • Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells
    • Itoh, R.E., Kurokawa, K., Ohba, Y., Yoshizaki, H., Mochizuki, N., and Matsuda, M. (2002). Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol. Cell. Biol. 22, 6582-6591.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6582-6591
    • Itoh, R.E.1    Kurokawa, K.2    Ohba, Y.3    Yoshizaki, H.4    Mochizuki, N.5    Matsuda, M.6
  • 12
    • 0032514214 scopus 로고    scopus 로고
    • Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity
    • Jou, T.S., and Nelson, W.J. (1998). Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity. J. Cell Biol. 142, 85-100.
    • (1998) J. Cell Biol. , vol.142 , pp. 85-100
    • Jou, T.S.1    Nelson, W.J.2
  • 13
    • 0037184967 scopus 로고    scopus 로고
    • Trans-interactions of nectins induce formation of filopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins
    • Kawakatsu, T., Shimizu, K., Honda, T., Fukuhara, T., Hoshino, T., and Takai, Y. (2002). Trans-interactions of nectins induce formation of filopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins. J. Biol. Chem. 277, 50749-50755.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50749-50755
    • Kawakatsu, T.1    Shimizu, K.2    Honda, T.3    Fukuhara, T.4    Hoshino, T.5    Takai, Y.6
  • 14
    • 0034711219 scopus 로고    scopus 로고
    • E-cadherin-mediated cell-cell attachment activates Cdc42
    • Kim, S.H., Li, Z., and Sacks, D.B. (2000). E-cadherin-mediated cell-cell attachment activates Cdc42. J. Biol. Chem. 275, 36999-37005.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36999-37005
    • Kim, S.H.1    Li, Z.2    Sacks, D.B.3
  • 15
    • 0032766006 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serin-threonine kinase Akt
    • Kitamura, T. et al. (1999). Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serin-threonine kinase Akt. Mol. Cell. Biol. 19, 6286-6296.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6286-6296
    • Kitamura, T.1
  • 16
    • 0033536245 scopus 로고    scopus 로고
    • Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells
    • Kodama, A., Takaishi, K., Nakano, K., Nishioka, H., and Takai, Y. (1999). Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells. Oncogene 18, 3996-4006.
    • (1999) Oncogene , vol.18 , pp. 3996-4006
    • Kodama, A.1    Takaishi, K.2    Nakano, K.3    Nishioka, H.4    Takai, Y.5
  • 17
    • 0037155159 scopus 로고    scopus 로고
    • E-Cadherin homophilic ligation directly signals through rac and phosphatidylinositol 3-kinase to regulate adhesive contacts
    • Kovacs, E.M., Ali, R.G., McCormack, A.J., and Yap, A.S. (2002). E-Cadherin homophilic ligation directly signals through rac and phosphatidylinositol 3-kinase to regulate adhesive contacts. J. Biol. Chem. 277, 6708-6718.
    • (2002) J. Biol. Chem. , vol.277 , pp. 6708-6718
    • Kovacs, E.M.1    Ali, R.G.2    McCormack, A.J.3    Yap, A.S.4
  • 19
    • 14444271574 scopus 로고    scopus 로고
    • Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction
    • Mandai, K. et al. (1997). Afadin: a novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. J. Cell Biol. 139, 517-528.
    • (1997) J. Cell Biol. , vol.139 , pp. 517-528
    • Mandai, K.1
  • 20
    • 0033535163 scopus 로고    scopus 로고
    • Ponsin/SH3P 12, an I-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions
    • Mandai, K., Nakanishi, H., Satoh, A., Takahashi, K., Satoh, K., Nishioka, H., Mizoguchi, A., and Takai, Y. (1999). Ponsin/SH3P 12, an I-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions. J. Cell Biol. 144, 1001-17.
    • (1999) J. Cell Biol. , vol.144 , pp. 1001-1017
    • Mandai, K.1    Nakanishi, H.2    Satoh, A.3    Takahashi, K.4    Satoh, K.5    Nishioka, H.6    Mizoguchi, A.7    Takai, Y.8
  • 21
    • 0034614555 scopus 로고    scopus 로고
    • Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction
    • Miyahara, M., Nakanishi, H., Takahashi, K., Satoh-Horikawa, K., Tachibana, K., and Takai, Y. (2000). Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction. J. Biol. Chem. 275, 613-618.
    • (2000) J. Biol. Chem. , vol.275 , pp. 613-618
    • Miyahara, M.1    Nakanishi, H.2    Takahashi, K.3    Satoh-Horikawa, K.4    Tachibana, K.5    Takai, Y.6
  • 24
    • 0035479827 scopus 로고    scopus 로고
    • Molecular architecture of adherens junctions
    • Nagafuchi, A. (2001). Molecular architecture of adherens junctions. Curr. Opin. Cell Biol. 13, 600-603.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 600-603
    • Nagafuchi, A.1
  • 25
    • 0023225108 scopus 로고
    • Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA
    • Nagafuchi, A., Shirayoshi, Y., Okazaki, K., Yasuda, K., and Takeichi, M. (1987). Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature 329, 341-343.
    • (1987) Nature , vol.329 , pp. 341-343
    • Nagafuchi, A.1    Shirayoshi, Y.2    Okazaki, K.3    Yasuda, K.4    Takeichi, M.5
  • 26
    • 0034994490 scopus 로고    scopus 로고
    • Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites
    • Nakagawa, M., Fukata, M., Yamaga, M., Itoh, N., and Kaibuchi, K. (2001). Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites. J. Cell Sci. 114, 1829-1838.
    • (2001) J. Cell Sci. , vol.114 , pp. 1829-1838
    • Nakagawa, M.1    Fukata, M.2    Yamaga, M.3    Itoh, N.4    Kaibuchi, K.5
  • 29
    • 0035479930 scopus 로고    scopus 로고
    • Intercellular junctions and cellular polarity: The PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity
    • Ohno, S. (2001). Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity. Curr. Opin. Cell Biol. 13, 641-648.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 641-648
    • Ohno, S.1
  • 31
    • 0033601948 scopus 로고    scopus 로고
    • Different behavior of I-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction
    • Sakisaka, T., Nakanishi, H., Takahashi, K., Mandai, K., Miyahara, M., Satoh, A., Takaishi, K., and Takai, Y. (1999). Different behavior of I-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction. Oncogene 18, 1609-1617.
    • (1999) Oncogene , vol.18 , pp. 1609-1617
    • Sakisaka, T.1    Nakanishi, H.2    Takahashi, K.3    Mandai, K.4    Miyahara, M.5    Satoh, A.6    Takaishi, K.7    Takai, Y.8
  • 32
    • 0034616002 scopus 로고    scopus 로고
    • Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities
    • Satoh-Horikawa, K., Nakanishi, H., Takahashi, K., Miyahara, M., Nishimura, M., Tachibana, K., Mizoguchi, A., and Takai, Y. (2000). Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities. J. Biol. Chem. 275, 10291-10299.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10291-10299
    • Satoh-Horikawa, K.1    Nakanishi, H.2    Takahashi, K.3    Miyahara, M.4    Nishimura, M.5    Tachibana, K.6    Mizoguchi, A.7    Takai, Y.8
  • 34
    • 0033519211 scopus 로고    scopus 로고
    • Nectin/PRR: An immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with afadin, a PDZ domain-containing protein
    • Takahashi, K. et al. (1999). Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with afadin, a PDZ domain-containing protein. J. Cell Biol. 145, 539-549.
    • (1999) J. Cell Biol. , vol.145 , pp. 539-549
    • Takahashi, K.1
  • 35
    • 0141813527 scopus 로고    scopus 로고
    • Nectins and nectin-like molecules: Roles in cell adhesion, migration, and polarization
    • Takai, Y., Irie, K., Shimizu, K., Sakisaka, T., and Ikeda, W. (2003). Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization. Cancer Sci. 94, 655-667.
    • (2003) Cancer Sci. , vol.94 , pp. 655-667
    • Takai, Y.1    Irie, K.2    Shimizu, K.3    Sakisaka, T.4    Ikeda, W.5
  • 36
    • 0037232646 scopus 로고    scopus 로고
    • Nectin and afadin: Novel organizers of intercellular junctions
    • Takai, Y., and Nakanishi, H. (2003). Nectin and afadin: novel organizers of intercellular junctions. J. Cell Sci. 116, 17-27.
    • (2003) J. Cell Sci. , vol.116 , pp. 17-27
    • Takai, Y.1    Nakanishi, H.2
  • 37
    • 0030718609 scopus 로고    scopus 로고
    • Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells
    • Takaishi, K., Sasaki, T., Kotani, H., Nishioka, H., and Takai, Y. (1997). Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J. Cell Biol. 139, 1047-1059.
    • (1997) J. Cell Biol. , vol.139 , pp. 1047-1059
    • Takaishi, K.1    Sasaki, T.2    Kotani, H.3    Nishioka, H.4    Takai, Y.5
  • 38
    • 0025894092 scopus 로고
    • Cadherin cell adhesion receptors as a morphogenetic regulator
    • Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
    • (1991) Science , vol.251 , pp. 1451-1455
    • Takeichi, M.1
  • 39
    • 0037458707 scopus 로고    scopus 로고
    • Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse
    • Takekuni, K., Ikeda, W., Fujito, T., Morimoto, K., Takeuchi, M., Monden, M., and Takai, Y. (2003). Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse. J. Biol. Chem. 278, 5497-5500.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5497-5500
    • Takekuni, K.1    Ikeda, W.2    Fujito, T.3    Morimoto, K.4    Takeuchi, M.5    Monden, M.6    Takai, Y.7
  • 40
    • 0034983715 scopus 로고    scopus 로고
    • WASP and WAVE family proteins: Key molecules for rapid rearrangement of cortical actin filaments and cell movement
    • Takenawa, T., and Miki, H. (2001). WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement. J. Cell Sci. 114, 1801-1809.
    • (2001) J. Cell Sci. , vol.114 , pp. 1801-1809
    • Takenawa, T.1    Miki, H.2
  • 41
    • 0033168966 scopus 로고    scopus 로고
    • Occludin and claudins in tight-junction strands: Leading or supporting players?
    • Tsukita, S., and Furuse, M. (1999). Occludin and claudins in tight-junction strands: leading or supporting players? Trends. Cell Biol. 9, 268-273.
    • (1999) Trends. Cell Biol. , vol.9 , pp. 268-273
    • Tsukita, S.1    Furuse, M.2
  • 42
    • 0034657319 scopus 로고    scopus 로고
    • Cadherin superfamily genes: Functions, genomic organization, and neurologic diversity
    • Yagi, T., and Takeichi, M. (2000). Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes Dev. 14, 1169-1180.
    • (2000) Genes Dev. , vol.14 , pp. 1169-1180
    • Yagi, T.1    Takeichi, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.