Identification of a binding site on human FGF-2 for fibrinogen

Blood

Volumn 103, Issue 6, 2004, Pages 2114-2120

  Peng, Hu ^b   Sahni, Abha ^b   Fay, Philip ^b   Bellum, Stephen ^b   Prudovsky, Igor ^b   Maciag, Thomas ^b   Francis, Charles W ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; FIBRIN; FIBRINOGEN; FIBROBLAST GROWTH FACTOR 2; MUTANT PROTEIN; PHENYLALANINE; SERINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; DISSOCIATION CONSTANT; ENDOTHELIUM CELL; GENE CASSETTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; UMBILICAL VEIN;

EID: 1542373660     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-08-2638     Document Type: Article

References (40)

1. Burgess WH, Maciag T. The heparin-binding (fibroblast) growth factor family of proteins. Annual Rev Biochem. 1989;58:575-606.
2. Bikfalvi A, Klein S, Pintucci G, et al. Biological roles of fibroblast growth factor-2. Endocr Rev. 1997;18:26-45.
3. Klagsbrun M. The fibroblast growth factor family: structural and biological properties. Prog Growth Factor Res. 1989;1:207-235.
4. Iozzo RV, San Antonio JD. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena. J Clin Invest. 2001;108:349-355.
5. Pellegrini L. Role of heparan sulfate in fibroblast growth factor signaling: a structural view. Curr Opin Struct Biol. 2001;11:629-634.
6. Schlessinger J, Plotnikov AN, Ibrahimi OA, et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell. 2000;6:743-750.
7. Hantgan RR, Simpson-Haidaris PJ, Francis CW, et al. Fibrinogen structure and physiology. In: Colman RW, Hirsh J, Marder VJ, et al, eds. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001:203-232.
8. Suehiro K, Mizuguchi J, Nishiyama K, et al. Fibrinogen binds to integrin alpha(5)beta(1) via the carboxyl-terminal RGD site of the Aalpha-chain. J Biochem (Tokyo). 2000;128:705-710.
9. Smith JW, Ruggeri ZM, Kunicki TJ, et al. Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen: differential peptide recognition accounts for distinct binding sites. J Biol Chem. 1990;265:12267-12271.
10. Pluskota E, D'Souza SE. Fibrinogen interactions with ICAM-1 (CD54) regulate endothelial cell survival. Eur J Biochem. 2000;267:4693-4704.
11. Kadish JL, Butterfield CE, Folkman J. The effect of fibrin on cultured vascular endothelial cells. Tissue Cell. 1979;11:99-108.
12. Watanabe K, Tanaka K. Influence of fibrin, fibrinogen and fibrinogen degradation products on cultured endothelial cells. Atherosclerosis. 1983;48:57-70.
13. Schleef RR, Birdwell CE. The effect of fibrin on endothelial cell migration in vitro. Tissue Cell. 1982;14:629-636.
14. Kaplan KL, Mather T, DeMarco L, et al. Effect of fibrin on endothelial cell production of prostacyclin and tissue plasminogen activator. Arteriosc, Thromb, and Vascular Biol. 1989;9:43-49.
15. Qi J, Kreutzer DL. Fibrin activation of vascular endothelial cells: induction of IL-8 expression. J Immunol. 1995;155:867-876.
16. Ribes JA, Francis CW, Wagner DD. Fibrin induces release of von Willebrand factor from endothelial cells. J Clin Invest. 1987;79:117-132.
17. Bunce LA, Sporn LA, Francis CW, Endothelial cell spreading on fibrin requires fibrinopeptide B cleavage and amino acid residues 15-42 of the beta chain. J Clin Invest. 1992;89:842-850.
18. Erban JK, Wagner DD. A 130-kDa protein on endothelial cells binds to amino acids 15-42 of the B beta chain of fibrinogen. J Biol Chem. 1992;267:2451-2458.
19. Bach TL, Barsigian C, Chalupowicz DG, et al. VE-cadherin mediates endothelial cell capillary tube formation in fibrin and collagen gels. Exp Cell Res. 1998;238:324-334.
20. Sahni A, Odrljin T, Francis CW. Binding of basic fibroblast growth factor to fibrinogen and fibrin. J Biol Chem. 1998;273:7554-7559.
21. Sahni A, Owen DA, Francis CW. FGF-2 but not FGF-1 binds fibrin and supports prolonged endothelial cell growth. J Thromb Haemost. 2003;1:1304-1310.
22. Sahni A, Sporn LA, Francis CW. Potentiation of endothelial cell proliferation by fibrin(ogen)-bound fibroblast growth factor-2. J Biol Chem. 1999;274:14936-14941.
23. Sahni A, Baker CA, Sporn LA, Francis CW. Fibrinogen and fibrin protect fibroblast growth factor-2 from proteolytic degradation. Thromb Haemost. 2000;83:736-741.
24. Sahni A, Francis CW. Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation. Blood. 2000;96:3772-3778.
25. Drew AF, Liu H, Davidson JM, et al. Wound-healing defects in mice lacking fibrinogen. Blood. 2001;97:3691-3698.
26. Blaber M, DiSalvo J, Thomas KA. X-ray crystal structure of human acidic fibroblast growth factor. Biochemistry. 1996;35:2086-2094.
27. Zhu X, Komiya H, Chirino A, et al. Three-dimensional structures of acidic and basic fibroblast growth factors. Science. 1991;251:90-93.
28. Pineda-Lucena A, Jimenez MA, Lozano RM, et al. Three-dimensional structure of acidic fibroblast growth factor in solution: effects of binding to a heparin functional analog. J Mol Biol. 1996;264:162-178.
29. Eriksson AE, Cousens LS, Weaver LH, Matthews BW. Three-dimensional structure of human basic fibroblast growth factor. Proc Natl Acad Sci U S A. 1991;88:3441-3445.
30. Zhang JD, Cousens LS, Barr PJ, Sprang SR. Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interlaukin 1 beta. Proc Natl Acad Sci U S A. 1991;88:3446-3450.
31. Imamura T, Friedman SA, Gamble S, et al. Identification of the domain within fibroblast growth factor-1 responsible for heparin-dependence. Biochim Biophys Acta. 1995;1266:124-130.
32. Munson PJ, Rodbard D. Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem. 1980;107:220-239.
33. Adams MD, Celniker SE, Holt RA, et al. The genome sequence of Drosophila melanogaster. Science. 2000;287:2185-2195.
34. The Washington University Genome Sequencing Center. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science. 1998;282:2012-2018.
35. Plotnikov AN, Schlessinger J, Stevan R, et al. Structural basis for FGF receptor dimerization and activation. Cell. 1999;98:641-650.
36. Springer BA, Pantoliano MW, Barbera FA, et al. Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis. J Biol Chem. 1994;269:26879-26884.
37. Venkataraman G, Raman R, Sasisekharan V, Sasisekharan R. Molecular characteristics of fibroblast growth factor-fibroblast growth factor receptor-heparin-like glycosaminoglycan complex. Proc Natl Acad Sci U S A. 1999;96:3658-3663.
38. Faham S, Hileman RE, Fromm RJ, et al. Heparin structure and interactions with basic fibroblast growth factor. Science. 1996;271:1116-1120.
39. Finzel BC, Clancy LL, Holland DR, et al. Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution. J Mol Biol. 1989;209:779-791.
40. Graves BJ, Hatada MH, Hendrickson WA, et al. Structure of interleukin 1 alpha at 2.7-A resolution. Biochemistry. 1990;29:2679-2684.