Electrophysiological Characterization of the Human Na +/Nucleoside Cotransporter 1 (hCNT1) and Role of Adenosine on hCNT1 Function

Journal of Biological Chemistry

Volumn 279, Issue 10, 2004, Pages 8999-9007

  Larráyoz, Ignacio M ^a   Casado, Francisco Javier ^b   Pastor Anglada, Marçal ^b   Lostao, M Pilar ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOELECTRIC POTENTIALS; BIOLOGICAL MEMBRANES; ELECTRIC CURRENTS; ELECTRODES; NITROGEN COMPOUNDS; REACTION KINETICS; SODIUM COMPOUNDS; TRANSPORT PROPERTIES;

NUCLEOSIDES; PYRIMIDINES;

ELECTROPHYSIOLOGY;

ADENOSINE; CYTIDINE; DOXIFLURIDINE; GEMCITABINE; HUMAN SODIUM NUCLEOSIDE COTRANSPORTER 1; NUCLEOSIDE TRANSPORTER; PYRIMIDINE; SODIUM ION; THYMIDINE; UNCLASSIFIED DRUG; URIDINE;

ANIMAL CELL; ARTICLE; ELECTROPHYSIOLOGY; HUMAN; HYPERPOLARIZATION; MEMBRANE POTENTIAL; MOLECULAR INTERACTION; MULTIGENE FAMILY; NONHUMAN; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STEADY STATE; STOICHIOMETRY; TRANSPORT KINETICS; VOLTAGE CLAMP;

ADENOSINE; ELECTROPHYSIOLOGY; HUMANS; KINETICS; SYMPORTERS;

ANIMALIA;

EID: 1542365250     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311940200     Document Type: Article

References (32)

1. Griffith, D. A., and Jarvis, S. M. (1996) Biochim. Biophys. Acta 1286, 153-181
2. Pastor-Anglada, M., Felipe, A., and Casado, F. J. (1998) Trends. Pharmacol. Sci. 19, 424-430
3. Baldwin, S. A., Mackey, J. R., Cass, C. E., and Young, J. D. (1999) Mol. Med. Today 5, 216-224
4. Casado, F. J., Lostao, M. P., Aymerich, I., Larrayoz, I. M., Duflot, S., Rodriguez-Mulero, S., and Pastor-Anglada, M. (2002) J. Physiol. Biochem. 58, 207-216
5. Ritzel, M. W., Ng, A. M., Yao, S. Y., Graham, K., Loewen, S. K., Smith, K. M., Ritzel, R. G., Mowles, D. A., Carpenter, P., Chen, X. Z., Karpinski, E., Hyde, R. J., Baldwin, S. A., Cass, C. E., and Young, J. D. (2001) J. Biol. Chem. 276, 2914-2927
6. Lostao, M. P., Mata, J. F., Larrayoz, I. M., Inzillo, S. M., Casado, F. J., and Pastor-Anglada, M. (2000) FEBS Lett. 481, 137-140
7. Mata, J. F., Garcia-Manteiga, J. M., Lostao, M. P., Fernandez-Veledo, S., Guillen-Gomez, E., Larrayoz, I. M., Lloberas, J., Casado, F. J., and Pastor-Anglada, M. (2001) Mol. Pharmacol. 59, 1542-1548
8. Mackey, J. R., Yao, S. Y., Smith, K. M., Karpinski, E., Baldwin, S. A., Cass, C. E., and Young, J. D. (1999) J. Natl. Cancer Inst. 91, 1876-1881
9. Dresser, M. J., Gerstin, K. M., Gray, A. T., Loo, D. D. F., and Giacomini, K. M. (2000) Drug Metab. Dispos. 28, 1135-1140
10. Gerstin, K. M., Dresser, M. J., and Giacomini, K. M. (2002) Am. J. Physiol. Renal Physiol. 283, 344-349
11. Yao, S. Y., Ng, A. M., Loewen, S. K., Cass, C. E., Baldwin, S. A., and Young, J. D. (2002) Am. J. Physiol. Cell Physiol. 283, 155-168
12. Loewen, S. K., Ng, A. M., Mohabir, N. N., Baldwin, S. A., Cass, C. E., and Young, J. D. (2003) Yeast 20, 661-675
13. Birnir, B., Loo, D. D., and Wright, E. M. (1991) Pfluegers Arch. 418, 79-85
14. Lostao, M. P., Hirayama, B. A., Loo, D. D., and Wright, E. M. (1994) J. Membr. Biol. 142, 161-170
15. Parent, L., Supplisson, S., Loo, D. D., and Wright, E. M. (1992) J. Membr. Biol. 126, 49-62
16. Loo, D. D., Hazama, A., Supplisson, S., Turk, E., and Wright, E. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5767-5771
17. Hazama, A., Loo, D. D., and Wright, E. M. (1997) J. Membr. Biol. 155, 175-186
18. Mackenzie, B., Loo, D. D., and Wright, E. M. (1998) J Membr. Biol 162, 101-106
19. Diez-Sampedro, A., Eskandari, S., Wright, E. M., and Hirayama, B. A. (2001) Am. J. Physiol. Renal Physiol. 280, 278-282
20. Loo, D. D., Eskandari, S., Boorer, K. J., Sarkar, H. K., and Wright, E. M. (2000) J. Biol. Chem. 275, 37414-37422
21. Yao, S. Y., Ng, A. M., Ritzel, M. W., Gati, W. P., Cass, C. E., and Young, J. D. (1996) Mol. Pharmacol. 50, 1529-1535
22. Fang, X., Parkinson, F. E., Mowles, D. A., Young, J. D., and Cass, C. E. (1996) Biochem. J. 317, 457-465
23. Ritzel, M. W., Yao, S. Y., Huang, M. Y., Elliott, J. F., Cass, C. E., and Young, J. D. (1997) Am. J. Physiol. 272, C707-C714
24. Mackenzie, B., Schafer, M. K., Erickson, J. D., Hediger, M. A., Weihe, E., and Varoqui, H. (2003) J. Biol. Chem. 278, 23720-23730
25. Forlani, G., Bossi, E., Perego, C., Giovannardi, S., and Peres, A. (2001) Biochim. Biophys. Acta 1538, 172-180
26. Klamo, E. M., Drew, M. E., Landfear, S. M., and Kavanaugh, M. P. (1996) J. Biol. Chem. 271, 14937-14943
27. Wadiche, J. I., Arriza, J. L., Amara, S. G., and Kavanaugh, M. P. (1995) Neuron 14, 1019-1027
28. Hirayama, B. A., Díez-Sampedro, A., and Wright, E. M. (2001) Br. J Pharmacol. 134, 484-495
29. Díez-Sampedro, A., Lostao, M. P., Wright, E. M., and Hirayama, B. A. (2000) J. Membr. Biol. 176, 111-117
30. Loewen, S. K., Ng, A. M., Yao, S. Y., Cass, C. E., Baldwin, S. A., and Young, J. D. (1999) J. Biol. Chem. 274, 24475-24484
31. Parent, L., Supplisson, S., Loo, D. D., and Wright, E. M. (1992) J. Membr. Biol. 125, 63-79
32. Weiss, J. N. (1997) FASEB J. 11, 835-841