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Volumn 7, Issue 2, 2004, Pages 189-195

Safe and acceptable strategies for producing foreign molecules in plants

Author keywords

Animal and Public Health Information System; APHIS; Industrial or pharmaceutical products; IPP; PHA; Polyhydroxyalkanoate; UAS; Upstream activating sequence; US Department of Agriculture; USDA

Indexed keywords

BIOTECHNOLOGY; GENETICS; METABOLISM; METHODOLOGY; REVIEW; SAFETY; TRANSGENE; TRANSGENIC PLANT;

EID: 1542351252     PISSN: 13695266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbi.2004.01.014     Document Type: Review
Times cited : (55)

References (49)
  • 1
    • 6444244303 scopus 로고    scopus 로고
    • Plants and human health in the twenty-first century
    • The authors discuss the rediscovery of the use of plants for medicinal, food and dietary supplement applications. They provide an exhaustive list of plant-derived pharmaceuticals and dietary supplements as well as a list of proteins under consideration for production in plants. They suggest that plants are "poised for a comeback" as sources of a variety of medicinal products.
    • Raskin I., Ribnicky D.M., Komarnytsky S., Ilis N., Poulev A., Borisuk N., Brinker A., Moreno D.A., Ripoll C., Yakoby N.et al. Plants and human health in the twenty-first century. Trends Biotechnol. 20:2002;522-531 The authors discuss the rediscovery of the use of plants for medicinal, food and dietary supplement applications. They provide an exhaustive list of plant-derived pharmaceuticals and dietary supplements as well as a list of proteins under consideration for production in plants. They suggest that plants are "poised for a comeback" as sources of a variety of medicinal products.
    • (2002) Trends Biotechnol , vol.20 , pp. 522-531
    • Raskin, I.1    Ribnicky, D.M.2    Komarnytsky, S.3    Ilis, N.4    Poulev, A.5    Borisuk, N.6    Brinker, A.7    Moreno, D.A.8    Ripoll, C.9    Yakoby, N.10
  • 2
    • 0141706699 scopus 로고    scopus 로고
    • The production of recombinant pharmaceutical proteins in plants
    • The authors review the benefits of recombinant protein production in plants. They provide a detailed list of the proteins being produced in plants and some of the safety issues that are associated with production of proteins in plants.
    • Ma J.K., Drake P.M.W., Christou P. The production of recombinant pharmaceutical proteins in plants. Nature Reviews. 4:2003;795-905 The authors review the benefits of recombinant protein production in plants. They provide a detailed list of the proteins being produced in plants and some of the safety issues that are associated with production of proteins in plants.
    • (2003) Nature Reviews , vol.4 , pp. 795-905
    • Ma, J.K.1    Drake, P.M.W.2    Christou, P.3
  • 3
    • 0032695044 scopus 로고    scopus 로고
    • GM crops: Public perception and scientific solutions
    • Daniell H. GM crops: public perception and scientific solutions. Trends Plant Sci. 4:1999;467-469.
    • (1999) Trends Plant Sci , vol.4 , pp. 467-469
    • Daniell, H.1
  • 4
    • 0033667765 scopus 로고    scopus 로고
    • Molecular farming of pharmaceutical proteins
    • Fischer R., Emans N. Molecular farming of pharmaceutical proteins. Transgenic Res. 9:2000;279-299.
    • (2000) Transgenic Res , vol.9 , pp. 279-299
    • Fischer, R.1    Emans, N.2
  • 5
    • 0036016077 scopus 로고    scopus 로고
    • Foods as production and delivery vehicles for human vaccines
    • Korban S.S., Krasnyanski S.F., Buetow D.E. Foods as production and delivery vehicles for human vaccines. J Am Coll Nutr. 21:2002;212S-217S.
    • (2002) J Am Coll Nutr , vol.21
    • Korban, S.S.1    Krasnyanski, S.F.2    Buetow, D.E.3
  • 6
    • 0033610015 scopus 로고    scopus 로고
    • New ways to glean medicines from plants
    • Gura T. New ways to glean medicines from plants. Science. 285:1999;1347-1349.
    • (1999) Science , vol.285 , pp. 1347-1349
    • Gura, T.1
  • 8
    • 0035939868 scopus 로고    scopus 로고
    • The battlefields of Britain
    • Gura T. The battlefields of Britain. Nature. 412:2001;760-763.
    • (2001) Nature , vol.412 , pp. 760-763
    • Gura, T.1
  • 9
    • 0037179710 scopus 로고    scopus 로고
    • Hostilities resume over future of GM crops
    • Adam D. Hostilities resume over future of GM crops. Nature. 419:2002;327.
    • (2002) Nature , vol.419 , pp. 327
    • Adam, D.1
  • 10
    • 0036903187 scopus 로고    scopus 로고
    • Agbiotech issues climb US political agenda
    • Fox J.L. Agbiotech issues climb US political agenda. Nat Biotechnol. 20:2002;1179-1180.
    • (2002) Nat Biotechnol , vol.20 , pp. 1179-1180
    • Fox, J.L.1
  • 11
    • 0242268545 scopus 로고    scopus 로고
    • Biosafety trials darken outlook for transgenic crops in Europe
    • Giles J. Biosafety trials darken outlook for transgenic crops in Europe. Nature. 425:2003;751.
    • (2003) Nature , vol.425 , pp. 751
    • Giles, J.1
  • 12
    • 0037809293 scopus 로고    scopus 로고
    • Trade war looms as US launches challenge over transgenic crops
    • Knight J. Trade war looms as US launches challenge over transgenic crops. Nature. 423:2003;369.
    • (2003) Nature , vol.423 , pp. 369
    • Knight, J.1
  • 14
    • 0141817963 scopus 로고    scopus 로고
    • GM crops: Science, politics and communication
    • A thoughtful and insightful discussion by several leading experts on GMO issues. The authors call for effective regulatory science as well as effective communication with consumers.
    • Arntzen C.J., Cochlan A., Johnson B., Peacock J., Rodemeyer M. GM crops: science, politics and communication. Nature Rev Genet. 4:2003;839-843 A thoughtful and insightful discussion by several leading experts on GMO issues. The authors call for effective regulatory science as well as effective communication with consumers.
    • (2003) Nature Rev Genet , vol.4 , pp. 839-843
    • Arntzen, C.J.1    Cochlan, A.2    Johnson, B.3    Peacock, J.4    Rodemeyer, M.5
  • 15
    • 0043208918 scopus 로고    scopus 로고
    • The science and politics of plant biotechnology - A personal perspective
    • Vasil I.K. The science and politics of plant biotechnology - a personal perspective. Nat Biotechnol. 21:2003;849-851.
    • (2003) Nat Biotechnol , vol.21 , pp. 849-851
    • Vasil, I.K.1
  • 16
    • 0037418894 scopus 로고    scopus 로고
    • Genomics, genetic engineering, and domestication of crops
    • Strauss S.H. Genomics, genetic engineering, and domestication of crops. Science. 300:2003;61-62.
    • (2003) Science , vol.300 , pp. 61-62
    • Strauss, S.H.1
  • 17
    • 18044366031 scopus 로고    scopus 로고
    • EPA re-evaluates StarLink license
    • Fox J.L. EPA re-evaluates StarLink license. Nat Biotechnol. 19:2001;11.
    • (2001) Nat Biotechnol , vol.19 , pp. 11
    • Fox, J.L.1
  • 18
    • 1542337982 scopus 로고    scopus 로고
    • USDA, EPA remove StarLink corn from feed
    • Fox J. USDA, EPA remove StarLink corn from feed. Nat Biotechnol. 19:2001;298.
    • (2001) Nat Biotechnol , vol.19 , pp. 298
    • Fox, J.1
  • 19
    • 0034323371 scopus 로고    scopus 로고
    • Taco dispute underscores need for standardized tests
    • Dorey E. Taco dispute underscores need for standardized tests. Nat Biotechnol. 18:2000;1136-1137.
    • (2000) Nat Biotechnol , vol.18 , pp. 1136-1137
    • Dorey, E.1
  • 20
    • 0034623847 scopus 로고    scopus 로고
    • Toxicology. Panel urges further study of biotech corn
    • Kaiser J. Toxicology. Panel urges further study of biotech corn. Science. 290:2000;1867.
    • (2000) Science , vol.290 , pp. 1867
    • Kaiser, J.1
  • 21
    • 84984933249 scopus 로고    scopus 로고
    • US processor rejects maize EU won't take
    • Wadman M. US processor rejects maize EU won't take. Nature. 398:1999;736.
    • (1999) Nature , vol.398 , pp. 736
    • Wadman, M.1
  • 25
    • 0038266834 scopus 로고    scopus 로고
    • Puzzling industry response to ProdiGene fiasco
    • Fox J.L. Puzzling industry response to ProdiGene fiasco. Nat Biotechnol. 21:2003;3-4.
    • (2003) Nat Biotechnol , vol.21 , pp. 3-4
    • Fox, J.L.1
  • 26
    • 1542367672 scopus 로고    scopus 로고
    • Permitting Genetically Engineered Plants That Produce Pharmaceutical Compounds
    • September
    • Anon: Permitting Genetically Engineered Plants That Produce Pharmaceutical Compounds. USDA Factsheet. September 2002.
    • (2002) USDA Factsheet
  • 27
    • 0013054225 scopus 로고    scopus 로고
    • Guidance for industry drugs, biologics, and medical devices derived from bioengineered plants for use in humans and animals, draft guidance
    • Docket No. 02D-0324, CBER 200134;
    • Anon: Guidance for industry drugs, biologics, and medical devices derived from bioengineered plants for use in humans and animals, draft guidance. Docket No. 02D-0324, CBER 200134; Federal Register 2002, 67:57828-57829.
    • (2002) Federal Register , vol.67 , pp. 57828-57829
  • 28
    • 0041411644 scopus 로고    scopus 로고
    • Field testing of plants engineered to produce pharmaceutical and industrial compounds
    • Docket No. 03-031-1, 7 CFR Part 340;
    • Anon: Field testing of plants engineered to produce pharmaceutical and industrial compounds. Docket No. 03-031-1, 7 CFR Part 340; Federal Register 2003, 68:11337-11340.
    • (2003) Federal Register , vol.68 , pp. 11337-11340
  • 29
    • 1542307860 scopus 로고    scopus 로고
    • Introductions of plants genetically engineered to produce industrial compounds
    • Docket No. 03-038-1, 7 CFR Part 340;
    • Anon: Introductions of plants genetically engineered to produce industrial compounds. Docket No. 03-038-1, 7 CFR Part 340; Federal Register 2003, 68:46434-46436.
    • (2003) Federal Register , vol.68 , pp. 46434-46436
  • 32
    • 0041602667 scopus 로고    scopus 로고
    • The biosafety of molecular farming in plants
    • The authors focus on biosafety concerns relating to the production of industrial or pharmaceutical products in plants. They review the concept of environmental pollution and contamination of the food supply with transgenes and proteins.
    • Commandeur U., Twyman R.M., Fischer R. The biosafety of molecular farming in plants. AgDiotechNet. 5:2003;1-9 The authors focus on biosafety concerns relating to the production of industrial or pharmaceutical products in plants. They review the concept of environmental pollution and contamination of the food supply with transgenes and proteins.
    • (2003) AgDiotechNet , vol.5 , pp. 1-9
    • Commandeur, U.1    Twyman, R.M.2    Fischer, R.3
  • 33
    • 1542277695 scopus 로고    scopus 로고
    • High-tech tomatoes get luxury residence
    • Anon: High-tech tomatoes get luxury residence. Nature 2003, 421:882.
    • (2003) Nature , vol.421 , pp. 882
  • 34
    • 0000721466 scopus 로고    scopus 로고
    • Seed-sterilizing 'terminator technology' sows discord
    • Service R.F. Seed-sterilizing 'terminator technology' sows discord. Science. 282:1998;850-851.
    • (1998) Science , vol.282 , pp. 850-851
    • Service, R.F.1
  • 35
    • 0034604442 scopus 로고    scopus 로고
    • USDA to commercialize 'terminator' technology
    • Kaiser J. USDA to commercialize 'terminator' technology. Science. 289:2000;709-710.
    • (2000) Science , vol.289 , pp. 709-710
    • Kaiser, J.1
  • 36
    • 0037780969 scopus 로고    scopus 로고
    • The basis of natural and artificial postzygotic hybridization barriers in Arabidopsis species
    • Bushell C., Spielman M., Scott R.J. The basis of natural and artificial postzygotic hybridization barriers in Arabidopsis species. Plant Cell. 15:2003;1430-1442.
    • (2003) Plant Cell , vol.15 , pp. 1430-1442
    • Bushell, C.1    Spielman, M.2    Scott, R.J.3
  • 37
    • 0033884980 scopus 로고    scopus 로고
    • Cell-type-specific calcium responses to drought, salt and cold in the Arabidopsis root
    • Kiegle E., Moore C.A., Haseloff J., Tester M.A., Knight M.R. Cell-type-specific calcium responses to drought, salt and cold in the Arabidopsis root. Plant J. 23:2000;267-278.
    • (2000) Plant J , vol.23 , pp. 267-278
    • Kiegle, E.1    Moore, C.A.2    Haseloff, J.3    Tester, M.A.4    Knight, M.R.5
  • 38
    • 0024979286 scopus 로고
    • Functional dissection and sequence of yeast HAP1 activator
    • Pfeifer K., Kim K.S., Kogan S., Guarente L. Functional dissection and sequence of yeast HAP1 activator. Cell. 56:1989;291-301.
    • (1989) Cell , vol.56 , pp. 291-301
    • Pfeifer, K.1    Kim, K.S.2    Kogan, S.3    Guarente, L.4
  • 40
    • 0032104487 scopus 로고    scopus 로고
    • The GCN4 motif in a rice glutin gene is essential for endosperm-specific gene expression and is activated by Opaque-2 in transgenic rice plants
    • Wu C.Y., Suzuki A., Washida H., Takaiwa F. The GCN4 motif in a rice glutin gene is essential for endosperm-specific gene expression and is activated by Opaque-2 in transgenic rice plants. Plant J. 14:1998;673-683.
    • (1998) Plant J , vol.14 , pp. 673-683
    • Wu, C.Y.1    Suzuki, A.2    Washida, H.3    Takaiwa, F.4
  • 42
    • 1542307862 scopus 로고    scopus 로고
    • Compositions containing glycopolypeptide multimers and methods of making same in plants. 17 June, 1997; US Patent 5,639,947. Epicyte
    • Hiatt AC, Hein MB: Compositions containing glycopolypeptide multimers and methods of making same in plants. 17 June, 1997; US Patent 5,639,947. Epicyte ( www.epicyte.com ).
    • Hiatt, A.C.1    Hein, M.B.2
  • 43
    • 1542367670 scopus 로고    scopus 로고
    • Production of polyhydroxy alkanoate in plants. 26 March, 1996; US Patent 5,502,273. Syngenta
    • Bright SWJ, Byrom D, Fentem PA: Production of polyhydroxy alkanoate in plants. 26 March, 1996; US Patent 5,502,273. Syngenta ( www.syngenta.com ).
    • Bright, S.W.J.1    Byrom, D.2    Fentem, P.A.3
  • 44
    • 1542367671 scopus 로고    scopus 로고
    • Oral immunization by transgenic plants. 5 August, 1997; US Patent 5,654,184. Dow
    • Curtiss R, Cardineau GA: Oral immunization by transgenic plants. 5 August, 1997; US Patent 5,654,184. Dow ( www.dow.com ).
    • Curtiss, R.1    Cardineau, G.A.2
  • 45
    • 1542307864 scopus 로고    scopus 로고
    • Vaccines expressed in plants. 24 October, 2000; US Patent 6,136,320. Prodigene
    • Arntzen CJ, Lam DM: Vaccines expressed in plants. 24 October, 2000; US Patent 6,136,320. Prodigene ( www.prodigene.com ).
    • Arntzen, C.J.1    Lam, D.M.2
  • 46
    • 1542307861 scopus 로고    scopus 로고
    • Accumulation of fructans in plants by targeted expression of bacterial levansucrase. 1999; US Patent 5,908,975. DuPont
    • Caimi PG, Hershey HP, Kerr PS: Accumulation of fructans in plants by targeted expression of bacterial levansucrase. 1999; US Patent 5,908,975. DuPont ( www.dupont.com ).
    • Caimi, P.G.1    Hershey, H.P.2    Kerr, P.S.3
  • 47
    • 1542307865 scopus 로고    scopus 로고
    • Process for producing transgenic inulin-generating plants. 2001; US Patent 6,255,562. KWS SAAT AG
    • Heyer AG, Wendenburg R: Process for producing transgenic inulin-generating plants. 2001; US Patent 6,255,562. KWS SAAT AG ( www.kws.de ).
    • Heyer, A.G.1    Wendenburg, R.2
  • 49
    • 1542277693 scopus 로고    scopus 로고
    • Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes. 31 May, 1994; US patent 5,316,931. Large Scale Biology
    • Donson J, Dawson WO, Granthan GL, Turpen TH, Turpen AM, Garger SJ, Grill LK: Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes. 31 May, 1994; US patent 5,316,931. Large Scale Biology ( www.lsbc.com ).
    • Donson, J.1    Dawson, W.O.2    Granthan, G.L.3    Turpen, T.H.4    Turpen, A.M.5    Garger, S.J.6    Grill, L.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.