Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1411-1416

  Wissner, Allan ^a   Hamann, Philip R ^a   Nilakantan, Ramaswamy ^a   Greenberger, Lee M ^a   Ye, Fei ^a   Rapuano, Timothy A ^a   Loganzo, Frank ^a  

^a WYETH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANIDE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR MODEL; STRUCTURE ANALYSIS; SYNTHESIS;

CELL LINE, TUMOR; ENZYME INHIBITORS; HUMANS; NAPHTHYRIDINES; NITRILES; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 1542345405     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.034     Document Type: Article

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