Peroxisomes and PPARs in cultured neural cells

Advances in Experimental Medicine and Biology

Volumn 544, Issue , 2003, Pages 271-280

  Cimini, Annamaria ^a   Cristiano, Loredana ^a   Bernardo, Antonietta ^b   Benedetti, Elisabetta ^a   Loreto, Silvia D I ^c   Cerù, Maria Paola ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c Ospedale S Maria di Collemaggio   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOIC ACID RECEPTOR;

CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CENTRAL NERVOUS SYSTEM; CONFERENCE PAPER; FATTY ACID TRANSPORT; HUMAN; INFLAMMATION; NERVE CELL; NONHUMAN; OLIGODENDROGLIA; PEROXISOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; GENE EXPRESSION; HUMANS; NEURONS; PEROXISOMES; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 1542343817     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (45)

1. Basu-Modak S., Braissant O., Escher P., Desvergne B., Honegger P., Wahli W.,1999, Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cultures. J. Biol. Chem. 274: 35881-35888.
2. Benani A., Krèmarik-Bouillaud P., Bianchi A., Netter P., Minn A., Dauça M., 2003, Evidence for the presence of both peroxisome proliferato-activated receptors alpha and beta in the rat spinal cord. J. Chem. Neuroanat. 25: 29-38
3. Blazquez C., Sanchez C., Velasco G. and Guzman M., 1998, Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes. J. Neurochem. 71: 1597-1606.
4. Boyles J.K., Pitas R.E., Wilson E., Mahley R.W. and Taylor J.M., 1985, Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J. Clin. Invest. 76: 1501-1503.
5. Braissant O., Foufelle F., Scotto O., Dauca M. and Wahli W., 1996, Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR α, β and γ in the adult rat. Endocrinology 137: 354-366.
6. Braissant O. and Wahli W., 1998, Differential expression of peroxime proliferator-activated receptor-α, -β and -γ during rat embryonic development Endocrinology 139: 2748-2754.
7. Campagnoni AT. and Macklin WB., 1988, Cellular and molecular aspects of posttrascriptional events in the myelin protein gene expression. Mol Neurol 21: 41-89.
8. Carmignoto G., 2000, Reciprocal communication systems between astrocytes and neurones. Progress in Neurobiology 62: 561-581.
9. Chattopadhyay N., Singh D., Heese O., Godbole M.M., Sinohara T., Balck T.M., Brown E., 2000, Expression of peroxisome proliferator-activated receptors (PPARs) in human astrocytic cells; PPARγ agonists as inducers of apoptosis. J. Neurosci. 61: 67-74.
10. Cimini A., Benedetti E., Cristiano L., Di Loreto S., 2003, Peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) expression during in vitro neuronal differentiation. submitted J. Neurochem.
11. Cimini A., Moreno S., Giorgi M., Serafini B., Cerù M.P., 1993, Purification of peroxisomal fractions from rat brain. Neurochem. Int. 23: 249-260.
12. Cimini A., Singh I., Farioli-Vecchioli S., Cristiano L., Cerù M.P., 1998, Presence of heterogeneous peroxisomal populations in the rat nervous tissue. Biochim. Biophys. Acta 1425: 13-26.
13. Cimini A., Bernardo A., Cifone M.G., Di Marzio L., Di Loreto S., 2003, TNFα downregulates PPARδ expression in oligodendrocyte progenitor cells: Implications for demyelinating diseases. Glia 41: 3-14.
14. Cristiano L., Bernardo A., Cerù M.P., 2001, Peroxisome proliferator-receptors (PPARs) and peroxisomes in rat cortical and cerebellar astyrocytes. J. Neurocytol. 30: 671-683.
15. Cullingford T.E., Bhakoo K., Peuchen S., Dolphin C.T., Patel R., Clark J.B., 1998, Distribution of mRNAs encoding the peroxisome proliferator- activated receptor alpha, beta, and gamma and the retinoid X receptor alpha, beta, and gamma in rat central nervous system. J. Neurochem. 70: 1366-1375.
16. Edmond J., 1992, Energy metabolism in developing brain cells. Cancer J. Physiol. Pharmacol. 70: S118-S129.
17. Fagan A.M. and Holtzman D.M., 2000, Astrocyte lipoproteins, effect of apoE on neuonal function and role of apoE in amyloid-beta deposition in vivo. Microscopy Res. Tech. 50: 297-304.
18. Farioli-Vecchioli S., Moreno S., Cerù M.P., 2001, Immunocytochemical localization of acyl-CoA oxidase in the rat central nervous system. J. Neurocytol. 30: 21-33.
19. Fouquet F., Zhou J.M., Raison E., Murray K., Troalen F., Magal E., Robain O., Dubois-Dalcq M., Aubourg P., 1997, Expression of the adrenoleukodystrophy protein in the human and mouse central nervous system. Neurobiol. Dis. 3: 271-285.
20. Granneman J., Skoff R., Yang X., 1998, Member of peroxisome proliferator-activated receptor family of transcription factors is differentially expressed by oligodendrocytes. J. Neurosci. Res. 51: 563-573.
21. Hamprecht B. and Dringen R., 1995, Energy Metabolism. In Neuroglia (H.H. Ketteman and B.R. Ransom eds.) Oxford University Press, New York, pp. 437-487.
22. Heneka M.T., Feinstein D., Galea E., Gleichmann M., Wullner U., Klockgether T., 1999, Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apopotic cell death by inhibition of inducible nitric oxide synthase. J. Neuroimmunol. 100: 156-168.
23. Heneka M.T., Klockgether T., Feinstein D.L., 2000, Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthetase expression and cell death in vivo. J. Neurosci. 20: 6882-6887
24. Kainu T., Wilkstrom A.C., Gustafsson J.A., Pelto-Huikko M., 1994, Localization of the peroxisome proliferator-activated receptor in the brain. Neuroreport 5: 2481-2485.
25. Kirino T. and Sano K., 1984, Selectively vulnerability in the gerbil hippocampus following transient ischemia. Acta Neuropathol. 62: 209-214.
26. Kliewer S.A., Forman B.M., Blumberg B., Ong E.S., Borgmeyer U., Mangelsdorf D.J., Umesono K., Evans R.M., 1994, Differential expresion and activation of a family of murine peroxisome proliferator-activated receptors Proc. Natl. Acad. Sci. USA 91: 7355-7359.
27. Krèmarik-Bouillaud P., Schohn H., Dauça M., 2000, Regional distribution of PPARβ in the cerebellum of the rat. J. Chem. Neuroanat. 19: 222-232.
28. Krey G., Braissant O., Kalkhoven L.H.F.E., Perroud M., Parker M.G., Wahli W., 1997, Fatty acids, eicosanoids and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 11: 779-791.
29. Lageweg W., Sykes J.E.C., Lopes-Cardozo M., Wanders R.J.A., 1991, Oxidation of very-long chain fatty acids in rat brain: cerotic acid is β-oxidized exclusively in rat brain peroxisomes. Biochim. Biophys. Acta 1085: 381-384.
30. Lopez-Cardozo M., Larsson O.M., Schonboe A., 1986, Acetoacetate and glucose as lipid precursors and energy substrates in primary cultures of astrocytes and neurons from mouse cerebral cortex. J. Neurochem. 46: 773-778.
31. Mangelsdorf D.J., Borgmeyer U., Heyman R.A., Zhou J.Y., Ong E.S., Oro A.E., KakizuKa A., Evans R.M., 1992, Characterization of three RXRgenes that mediate the action of 9-cis-retinoic acid. Genes Dev. 6: 329-344.
32. Medina J. and Tabernero A., 2002, Astrocyte-synthesized oleic acid behaves as neurotrofic factor for neurons. J. Physiol. 96: 265-271.
33. Moreno S., Mugnaini E., Cerù M.P., 1995, Immunocytochemical localization of catalase in the central nervous system of the rat. J. Histochem. Cytochem. 43: 1253-1267.
34. Moreno S., Nardacci E., Cerù M.P., 1997, Regional and ultrastructural immunolocalization of copper-zinc superoxide dismutase in rat central nervous system. J. Histochem. Cytochem. 45: 1611-1622.
35. Moreno S., Nardacci R., Cimini A., Cerù M.P., 2000, Immunocytochemical localization of D-aminoacid oxidase in rat brain. J. Neurocytol. 28: 169-185.
36. Moreno S., Farioli-Vecchioli S., Cerù M.P., Immunolocalization of peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) in the rat central nervous system, submitted
37. Pellerin L., Stolz M., Sorg O., Martin J.L., Deschepper C.F., Magistretti P.J., 1997, Regulation of energy metabolism by neurotransmitters in astrocytes in primary culture and in immortalized cell line. Glia 21: 74-83.
38. Peuchen S., Bolanos J.P., Heales S.J.R., Almeida A., Duchen M.R., Clark J.B., 1997, Interrelationship between astrocyte function, oxidative stress and anti-oxidant status within the central nervous system. Progress Neurobiol. 52: 261-281.
39. Rohn T.T., Wong S.M., Cotman C.W., Cribbo D.H., 2001, 15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptotis. Neuroreport 12: 839-843.
40. Saluja I., Grannemann J.G., Skoff R., 2001, PPAR delta agonists stimulate oligodendrocytes differentiation in tissue culture. Glia 33: 191-204.
41. Siesjo B.K., 1981, Cell damage in the brain: a speculative synthesis. J. Cerebr. Blood Flow Metab. 1: 155-160.
42. Tabernero A., Lavado E.M., Granda B., Velasco A., Medina J., 2001, Neuronal differentiation is triggered by oleic acid synthetisized and released by astrocytes. J. Neurochem. 79: 606-616.
43. Travis J., 1994, Glia: the brain's other cells. Science 266: 970-972.
44. Vanden Heuvel J.P., 1999, Peroxisome proliferator-activated receptors: a critical link among fatty acids, gene expression and carcinogenesis. J. Nutr. 129: 575S-580S.
45. Wilson J.X., 1997, Antioxidant defence of the brain: A role for astrocytes. Cancer J. Physiol. Pharmacol. 75: 261-281.