메뉴 건너뛰기




Volumn 75, Issue 6, 2004, Pages 751-759

Binding and Transport of [3H](2S,4R)-4-Methylglutamate, a New Ligand for Glutamate Transporters, Demonstrate Labeling of EAAT1 in Cultured Murine Astrocytes

Author keywords

Brain; D aspartate; Excitatory amino acid; Glia, uptake

Indexed keywords

2 (CARBOXYCYLOPROPYL)GLYCINE; 3 METHYLGLUTAMATE; 4 METHYLGLUTAMIC ACID; ASPARTIC ACID; CARBOXYLIC ACID DERIVATIVE; DIHYDROKAINIC ACID; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; GLYCINE DERIVATIVE; KAINIC ACID; LIGAND; POTASSIUM ION; PYRROLIDINE 2,4 DICARBOXYLATE; SERINE DERIVATIVE; SERINE SULFATE; SODIUM ION; UNCLASSIFIED DRUG; (ALPHA CARBOXYCYCLOPROPYL)GLYCINE; (ALPHA-CARBOXYCYCLOPROPYL)GLYCINE; 4-METHYLGLUTAMIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; DEXTRO ASPARTIC ACID; DICARBOXYLIC AMINO ACID; DRUG DERIVATIVE; EXCITATORY AMINO ACID TRANSPORTER 1; POTASSIUM; SERINE; SERINE O-SULFATE; SODIUM; TRITIUM;

EID: 1542304461     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20013     Document Type: Article
Times cited : (31)

References (45)
  • 4
    • 0015426691 scopus 로고
    • The structural specificity of the high affinity uptake of L-glutamate and L-aspartate by rat brain slices
    • Balcar VJ, Johnston GA. 1972. The structural specificity of the high affinity uptake of L-glutamate and L-aspartate by rat brain slices. J Neurochem 19:2657-2666.
    • (1972) J Neurochem , vol.19 , pp. 2657-2666
    • Balcar, V.J.1    Johnston, G.A.2
  • 5
    • 0026705561 scopus 로고
    • Heterogeneity of high affinity uptake of L-glutamate and L-aspartate in the mammalian central nervous system
    • Balcar VJ, Li Y. 1992. Heterogeneity of high affinity uptake of L-glutamate and L-aspartate in the mammalian central nervous system. Life Sci 51: 1467-1478.
    • (1992) Life Sci , vol.51 , pp. 1467-1478
    • Balcar, V.J.1    Li, Y.2
  • 7
    • 0032192550 scopus 로고    scopus 로고
    • Neuropharmacology of AMPA and kainate receptors
    • Bleakman D, Lodge D. 1998. Neuropharmacology of AMPA and kainate receptors. Neuropharmacology 37:1187-1204.
    • (1998) Neuropharmacology , vol.37 , pp. 1187-1204
    • Bleakman, D.1    Lodge, D.2
  • 8
    • 0032937403 scopus 로고    scopus 로고
    • A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system
    • Bridges RJ, Kavanaugh MP, Chamberlin AR. 1999. A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system. Curr Pharm Des 5:363-379.
    • (1999) Curr Pharm Des , vol.5 , pp. 363-379
    • Bridges, R.J.1    Kavanaugh, M.P.2    Chamberlin, A.R.3
  • 11
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC. 2001. Glutamate uptake. Prog Neurobiol 65:1-105.
    • (2001) Prog Neurobiol , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 12
    • 49749211426 scopus 로고
    • Plaque production by the Polyoma virus
    • Dulbecco R, Freeman G. 1959. Plaque production by the Polyoma virus. Virology 8:396-397.
    • (1959) Virology , vol.8 , pp. 396-397
    • Dulbecco, R.1    Freeman, G.2
  • 13
    • 0000974147 scopus 로고    scopus 로고
    • Excitatory amino acid transporters as emerging targets for central nervous system therapeutics
    • Dunlop J, Zaleska MM, Eliasof S, Moyer JA. 1999. Excitatory amino acid transporters as emerging targets for central nervous system therapeutics. Emerg Ther Targets 3:543-570.
    • (1999) Emerg Ther Targets , vol.3 , pp. 543-570
    • Dunlop, J.1    Zaleska, M.M.2    Eliasof, S.3    Moyer, J.A.4
  • 14
    • 0029943301 scopus 로고    scopus 로고
    • Tumor necrosis factor α inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia
    • Fine SM, Angel RA, Perry SW, Epstein LG, Rothstein JD, Dewhurst S, Gelbard HA. 1996. Tumor necrosis factor α inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. J Biol Chem 271:15303-15306.
    • (1996) J Biol Chem , vol.271 , pp. 15303-15306
    • Fine, S.M.1    Angel, R.A.2    Perry, S.W.3    Epstein, L.G.4    Rothstein, J.D.5    Dewhurst, S.6    Gelbard, H.A.7
  • 15
    • 0030657941 scopus 로고    scopus 로고
    • Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia
    • Gegelashvili G, Danbolt NC, Schousboe A. 1997. Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. J Neurochem 69:2612-2615.
    • (1997) J Neurochem , vol.69 , pp. 2612-2615
    • Gegelashvili, G.1    Danbolt, N.C.2    Schousboe, A.3
  • 16
    • 0024314299 scopus 로고
    • Inhibition by excitatory sulphur amino acids of the high-affinity L-glutamate transporter in synaptosomes and in primary cultures of cortical astrocytes and cerebellar neurons
    • Griffiths R, Grieve A, Dunlop J, Damgaard I, Fosmark H, Schousboe A. 1989. Inhibition by excitatory sulphur amino acids of the high-affinity L-glutamate transporter in synaptosomes and in primary cultures of cortical astrocytes and cerebellar neurons. Neurochem Res 14:333-343.
    • (1989) Neurochem Res , vol.14 , pp. 333-343
    • Griffiths, R.1    Grieve, A.2    Dunlop, J.3    Damgaard, I.4    Fosmark, H.5    Schousboe, A.6
  • 18
    • 0017839638 scopus 로고
    • Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures
    • Hertz L, Schousboe A, Boechler N, Mukerji S, Fedoroff S. 1978. Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures. Neurochem Res 3:1-14.
    • (1978) Neurochem Res , vol.3 , pp. 1-14
    • Hertz, L.1    Schousboe, A.2    Boechler, N.3    Mukerji, S.4    Fedoroff, S.5
  • 20
    • 0028958939 scopus 로고
    • Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations
    • Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, Danbolt NC. 1995. Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J Neurosci 15:1835-1853.
    • (1995) J Neurosci , vol.15 , pp. 1835-1853
    • Lehre, K.P.1    Levy, L.M.2    Ottersen, O.P.3    Storm-Mathisen, J.4    Danbolt, N.C.5
  • 21
    • 0028347852 scopus 로고
    • 3H]L-aspartate in thaw-mounted sections of rat forebrain
    • 3H]L-aspartate in thaw-mounted sections of rat forebrain. Exp Brain Res 97:415-422.
    • (1994) Exp Brain Res , vol.97 , pp. 415-422
    • Li, Y.1    Balcar, V.J.2
  • 22
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy KD, de Vellis J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85:890-902.
    • (1980) J Cell Biol , vol.85 , pp. 890-902
    • McCarthy, K.D.1    De Vellis, J.2
  • 23
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN. 1996. Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 19:331-338.
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 24
    • 0036400305 scopus 로고    scopus 로고
    • Roles and regulation of glutamate transporters in the central nervous system
    • O'Shea RD. 2002. Roles and regulation of glutamate transporters in the central nervous system. Clin Exp Pharmacol Physiol 29:1018-1023.
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , pp. 1018-1023
    • O'Shea, R.D.1
  • 26
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes-cellular and molecular cues to biological function
    • Ridet JL, Malhotra SK, Privat A, Gage FH. 1997. Reactive astrocytes-cellular and molecular cues to biological function. Trends Neurosci 20:570-577.
    • (1997) Trends Neurosci , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 27
    • 0034688312 scopus 로고    scopus 로고
    • Glutamate release in severe brain ischaemia is mainly by reversed uptake
    • Rossi DJ, Oshima T, Attwell D. 2000. Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403:316-321.
    • (2000) Nature , vol.403 , pp. 316-321
    • Rossi, D.J.1    Oshima, T.2    Attwell, D.3
  • 29
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW. 1995. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38:73-84.
    • (1995) Ann Neurol , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 31
    • 0017718021 scopus 로고
    • Uptake and metabolism of glutamate in astrocytes cultured from dissociated mouse brain hemispheres
    • Schousboe A, Svenneby G, Hertz L. 1977. Uptake and metabolism of glutamate in astrocytes cultured from dissociated mouse brain hemispheres. J Neurochem 29:999-1005.
    • (1977) J Neurochem , vol.29 , pp. 999-1005
    • Schousboe, A.1    Svenneby, G.2    Hertz, L.3
  • 32
    • 0028168346 scopus 로고
    • 3H]D-aspartate binding sites in the normal human spinal cord and changes in motor neuron disease: A quantitative autoradiographic study
    • 3H]D-aspartate binding sites in the normal human spinal cord and changes in motor neuron disease: a quantitative autoradiographic study. Brain Res 655:195-201.
    • (1994) Brain Res , vol.655 , pp. 195-201
    • Shaw, P.J.1    Chinnery, R.M.2    Ince, P.G.3
  • 33
    • 0031081439 scopus 로고    scopus 로고
    • Stimulation of glutamate uptake and Na,K-ATPase activity in rat astrocytes exposed to ischemia-like insults
    • Stanimirovic DB, Ball R, Durkin JP. 1997. Stimulation of glutamate uptake and Na,K-ATPase activity in rat astrocytes exposed to ischemia-like insults. Glia 19:123-134.
    • (1997) Glia , vol.19 , pp. 123-134
    • Stanimirovic, D.B.1    Ball, R.2    Durkin, J.P.3
  • 34
    • 0033053566 scopus 로고    scopus 로고
    • Developmental regulation of glutamate transporters and glutamine synthetase activity in astrocyte cultures differentiated in vitro
    • Stanimirovic DB, Ball R, Small DL, Muruganandam A. 1999. Developmental regulation of glutamate transporters and glutamine synthetase activity in astrocyte cultures differentiated in vitro. Int J Dev Neurosci 17:173-184.
    • (1999) Int J Dev Neurosci , vol.17 , pp. 173-184
    • Stanimirovic, D.B.1    Ball, R.2    Small, D.L.3    Muruganandam, A.4
  • 37
    • 0030946093 scopus 로고    scopus 로고
    • Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2
    • Vandenberg RJ, Mitrovic AD, Chebib M, Balcar VJ, Johnston GA. 1997. Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2. Mol Pharmacol 51:809-815.
    • (1997) Mol Pharmacol , vol.51 , pp. 809-815
    • Vandenberg, R.J.1    Mitrovic, A.D.2    Chebib, M.3    Balcar, V.J.4    Johnston, G.A.5
  • 38
    • 0031953098 scopus 로고    scopus 로고
    • Serine-O-sulphate transport by the human glutamate transporter, EAAT2
    • Vandenberg RJ, Mitrovic AD, Johnston GA. 1998. Serine-O-sulphate transport by the human glutamate transporter, EAAT2. Br J Pharmacol 123:1593-1600.
    • (1998) Br J Pharmacol , vol.123 , pp. 1593-1600
    • Vandenberg, R.J.1    Mitrovic, A.D.2    Johnston, G.A.3
  • 39
  • 42
    • 0028357664 scopus 로고
    • Willardiines differentiate agonist binding sites for kainate-versus AMPA-preferring glutamate receptors in DRG and hippocampal neurons
    • Wong LA, Mayer ML, Jane DE, Watkins JC. 1994. Willardiines differentiate agonist binding sites for kainate-versus AMPA-preferring glutamate receptors in DRG and hippocampal neurons. J Neurosci 14:3881-3897.
    • (1994) J Neurosci , vol.14 , pp. 3881-3897
    • Wong, L.A.1    Mayer, M.L.2    Jane, D.E.3    Watkins, J.C.4
  • 43
    • 0031753291 scopus 로고    scopus 로고
    • A culture model of reactive astrocytes: Increased nerve growth factor synthesis and reexpression of cytokine responsiveness
    • Wu VW, Nishiyama N, Schwartz JP. 1998. A culture model of reactive astrocytes: increased nerve growth factor synthesis and reexpression of cytokine responsiveness. J Neurochem 71:749-756.
    • (1998) J Neurochem , vol.71 , pp. 749-756
    • Wu, V.W.1    Nishiyama, N.2    Schwartz, J.P.3
  • 44
    • 0032520893 scopus 로고    scopus 로고
    • Cell culture models for reactive gliosis: New perspectives
    • Wu VW, Schwartz JP. 1998. Cell culture models for reactive gliosis: new perspectives. J Neurosci Res 51:675-681.
    • (1998) J Neurosci Res , vol.51 , pp. 675-681
    • Wu, V.W.1    Schwartz, J.P.2
  • 45
    • 0029804572 scopus 로고    scopus 로고
    • Cytokine modulation of glial glutamate uptake: A possible involvement of nitric oxide
    • Ye ZC, Sontheimer H. 1996. Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide. Neuroreport 7:2181-2185.
    • (1996) Neuroreport , vol.7 , pp. 2181-2185
    • Ye, Z.C.1    Sontheimer, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.