Agonist-activated glucocorticoid receptor inhibits binding of heat shock factor 1 to the heat shock protein 70 promoter in vivo

Molecular Endocrinology

Volumn 18, Issue 3, 2004, Pages 500-508

  Wadekar, Subhagya A ^a   Li, Dapei ^a   Sánchez, Edwin R ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENITE SODIUM; CHLORAMPHENICOL ACETYLTRANSFERASE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN; HORMONE; ISOPROTEIN; MIFEPRISTONE; MUTANT PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL NUCLEUS; CHROMATIN; CONTROLLED STUDY; FRACTIONATION; GENE EXPRESSION; HEAT; HUMAN; IMMUNOPRECIPITATION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRESS; TIME;

ANIMALS; CELLS, CULTURED; DEXAMETHASONE; DNA-BINDING PROTEINS; GLUCOCORTICOIDS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MICE; PROMOTER REGIONS (GENETICS); RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; TIME FACTORS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 1542267687     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2003-0215     Document Type: Article

References (28)

1. Evans RM 1988 The steroid and thyroid hormone receptor superfamily. Science 240:889-895
2. Munck A, Guyre PM, Holbrook NJ 1984 Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr Rev 5:25-44
3. Sapolsky RM, Romero LM, Munck AU 2000 How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev 21:55-89
4. Wadekar SA, Li D, Periyasamy S, Sanchez ER 2001 Inhibition of heat shock transcription factor by glucocorticoid receptor. Mol Endocrinol 15:1396-1410
5. Chandran UR, Attardi B, Friedman R, Zheng Z, Roberts JL, DeFranco DB 1996 Glucocorticoid repression of the mouse gonadotropin-releasing hormone gene is mediated by promoter elements that are recognized by heteromeric complexes containing glucocorticoid receptor. J Biol Chem 271:20412-20420
6. Sakai DD, Helms S, Carlstedt-Duke J, Gustafsson J-A, Rottman FM, Yamamoto KR 1988 Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. Genes Dev 2:1144-1154
7. Subramaniam N, Cairns W, Okret S 1997 Studies on the mechanism of glucocorticoid-mediated repression from a negative glucocorticoid response element from the bovine prolactin gene. DNA Cell Biol 16:153-163
8. Malkoski SP, Dorin RI 1999 Composite glucocorticoid regulation at a functionally defined negative glucocorticoid response element of the human corticotropin-releasing hormone gene. Mol Endocrinol 13:1629-1644
9. Schiller P, Amin J, Ananthan J, Brown ME, Scott WA, Voellmy R 1988 Cis-acting elements involved in the regulated expression of a human HSP70 gene. J Mol Biol 203:97-105
10. Kuo MH, Allis CD 1999 In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment. Methods 19: 425-433
11. Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M 2000 Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103:843-852
12. Nissen RM, Yamamoto KR 2000 The glucocortlcoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev 14:2314-229
13. Orlando V 2000 Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation. Trends Biochem Sci 25:99-104
14. Lambert JR, Nordeen SK 2001 Analysis of steroid hormone-induced histone acetylation by chromatin immunoprecipitation assay. Methods Mol Biol 176:273-281
15. Freeman BC, Yamamoto KR 2002 Disassembly of transcriptional regulatory complexes by molecular chaperones. Science 296:2232-2235
16. Sanchez ER, Meshinchi S, Tienrungroj W, Schlesinger MJ, Toft DO, Pratt WB 1987 Relationship of the 90-kDa murlne heat shock protein to the untransformed and transformed states of the L cell glucocorticoid receptor. J Biol Chem 262:6986-6991
17. Sanchez ER, Hirst M, Scherrer LC, Tang HY, Welsh MJ, Harmon JM, Simons SSJ, Ringold GM, Pratt WB 1990 Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90. J Biol Chem 265:20123-20130
18. Morimoto RI 1993 Cells in stress: transcriptional activation of heat shock genes. Science 259:1409-1410
19. Guo Y, Guettouche T, Fenna M, Boellmann F, Pratt WB, Toft DO, Smith DF, Voellmy R 2001 Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex. J Biol Chem 276: 45791-45799
20. Bodwell JE, Orti E, Coull JM, Pappin DJ, Smith LI, Swift F 1991 Identification of phosphorylated sites in the mouse glucocorticoid receptor. J Biol Chem 266:7549-7555
21. Dreano M, Brochot J, Myers A, Cheng-Meyer C, Rungger C, Voellmy R, Bromley P 1986 High-level, heat-regulated synthesis of proteins in eukaryotic cells. Gene 49:1-8
22. Cato AC, Miksicek R, Schutz G, Arnemann J, Beato M 1986 The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction. EMBO J 5:2237-2240
23. Gossen M, Freundlieb S, Bender G, Muller G, Hillen W, Bujard H 1995 Transcriptional activation by tetracyclines in mammalian cells. Science 268:1766-1769
24. Zuo J, Rungger D, Voellmy R 1995 Multiple layers of regulation of human heat shock transcription factor 1. Mol Cell Biol 15:4319-4330
25. Sanchez ER, Hu JL, Zhong S, Shen P, Greene MJ, Housley PR 1994 Potentiation of glucocorticoid receptor-mediated gene expression by heat and chemical shock. Mol Endocrinol 8:408-421
26. Li DP, Li Calzi S, Sanchez ER 1999 Inhibition of heat shock factor activity prevents heat shock potentiation of glucocorticoid receptor-mediated gene expression. Cell Stress Chaperones 4:223-234
27. Nordeen SK, Green III PP, Fowlkes DM 1987 A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferase. DNA 6:173-178
28. Tienrungroj W, Sanchez ER, Housley PR, Harrison RW, Pratt WB 1987 Glucocorticoid receptor phosphorylation, transformation, and DNA binding. J Biol Chem 262: 17342-17349