Mathematical analysis demonstrates that interferons-β and -γ Interact in a multiplicative manner to disrupt herpes simplex virus replication

Journal of Theoretical Biology

Volumn 234, Issue 3, 2005, Pages 439-454

  Halford, William P ^a,c   Halford, Keith J ^b   Pierce, Amy T ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b U S GEOLOGICAL SURVEY   (United States)

^c MONTANA STATE UNIVERSITY   (United States)

Author keywords

Herpesvirus; Interferon; Latent infection; Multiplicative interaction; Synergy

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON;

MATHEMATICAL ANALYSIS; THEORETICAL STUDY;

ACCURACY; ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; HERPES SIMPLEX VIRUS; HERPES SIMPLEX VIRUS 1; HOST; LATENT PERIOD; LEUKOCYTE; LIFESPAN; MATHEMATICAL ANALYSIS; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INFECTION; VIRUS INHIBITION; VIRUS REPLICATION;

CYTOMEGALOVIRUS; HERPES; HERPESVIRIDAE; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 15244352102     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtbi.2004.12.007     Document Type: Article

References (55)

1. D.S. Aaronson, and C.M. Horvath A road map for those who don't know JAK-STAT Science 296 5573 2002 1653 1655
2. C. Anstey A new model for the oxyhaemoglobin dissociation curve Anaesth. Intensive Care 31 4 2003 376 387
3. M.J. Balish, M.E. Abrams, A.M. Pumfery, and C.R. Brandt Enhanced inhibition of herpes simplex virus type 1 growth in human corneal fibroblasts by combinations of interferon-alpha and-gamma J. Infect. Dis. 166 6 1992 1401 1403
4. M.C. Berenbaum What is synergy? Pharmacol. Rev. 41 2 1989 93 141
5. E. Cantin, B. Tanamachi, and H. Openshaw Role for gamma interferon in control of herpes simplex virus type 1 reactivation J. Virol. 73 4 1999 3418 3423
6. E. Cantin, B. Tanamachi, H. Openshaw, J. Mann, and K. Clarke Gamma interferon (IFN-gamma) receptor null-mutant mice are more susceptible to herpes simplex virus type 1 infection than IFN-gamma ligand null-mutant mice J. Virol. 73 6 1999 5196 5200
7. A.V. Chee, P. Lopez, P.P. Pandolfi, and B. Roizman Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects J. Virol. 77 12 2003 7101 7105
8. J. Chehimi, and G. Trinchieri Interleukin-12 a bridge between innate resistance and adaptive immunity with a role in infection and acquired immunodeficiency J. Clin. Immunol. 14 3 1994 149 161
9. S.H. Chen, J.E. Oakes, and R.N. Lausch Synergistic anti-HSV effect of tumor necrosis factor alpha and interferon gamma in human corneal fibroblasts is associated with interferon beta induction Antiviral Res. 22 1 1993 15 29
10. C.W. Czarniecki, C.W. Fennie, D.B. Powers, and D.A. Estell Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons J. Virol. 49 2 1984 490 496
11. V. Dressler, G. Muller, and J. Suhnel CombiTool - a new computer program for analyzing combination experiments with biologically active agents Comput. Biomed. Res. 32 2 1999 145 160
12. M.A. Farrar, and R.D. Schreiber The molecular cell biology of interferon-gamma and its receptor Annu. Rev. Immunol. 11 1993 571 611
13. G.F. Gebhart Comments on the isobole method for analysis of drug interactions Pain 51 3 1992 381 author reply 383-388
14. W.R. Greco, G. Bravo, and J.C. Parsons The search for synergy a critical review from a response surface perspective Pharmacol. Rev. 47 2 1995 331 385
15. L.G. Guidotti, K. Ando, M.V. Hobbs, T. Ishikawa, L. Runkel, R.D. Schreiber, and F.V. Chisari Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice Proc. Natl Acad. Sci. USA 91 9 1994 3764 3768
16. L.G. Guidotti, T. Ishikawa, M.V. Hobbs, B. Matzke, R. Schreiber, and F.V. Chisari Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes Immunity 4 1 1996 25 36
17. L.G. Guidotti, R. Rochford, J. Chung, M. Shapiro, R. Purcell, and F.V. Chisari Viral clearance without destruction of infected cells during acute HBV infection Science 284 5415 1999 825 829
18. W.P. Halford, B.M. Gebhardt, and D.J. Carr Persistent cytokine expression in trigeminal ganglion latently infected with herpes simplex virus type 1 J. Immunol. 157 8 1996 3542 3549
19. M. Karaghiosoff, R. Steinborn, P. Kovarik, G. Kriegshauser, M. Baccarini, B. Donabauer, U. Reichart, T. Kolbe, C. Bogdan, T. Leanderson, D. Levy, T. Decker, and M. Muller Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock Nat. Immunol. 4 5 2003 471 477
20. K. Khanna, R. Bonneau, P. Kinchington, and R. Hendricks Herpes simplex virus-specific memory CD8(+) T cells are selectively activated and retained in latently infected sensory ganglia Immunity 18 5 2003 593 603
21. D.M. Koelle, C.M. Posavad, G.R. Barnum, M.L. Johnson, J.M. Frank, and L. Corey Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes J. Clin. Invest. 101 7 1998 1500 1508
22. D.E. Levy, and J.E. Darnell Jr. Stats transcriptional control and biological impact Nat. Rev. Mol. Cell Biol. 3 9 2002 651 662
23. L.A. Lieberman, and C.A. Hunter Regulatory pathways involved in the infection-induced production of IFN-gamma by NK cells Microbes Infect. 4 15 2002 1531 1538
24. T. Liu, Q. Tang, and R.L. Hendricks Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection J. Virol. 70 1 1996 264 271
25. T. Liu, K.M. Khanna, X. Chen, D.J. Fink, and R.L. Hendricks CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons J. Exp. Med. 191 9 2000 1459 1466
26. T. Liu, K.M. Khanna, B.N. Carriere, and R.L. Hendricks Gamma interferon can prevent herpes simplex virus type 1 reactivation from latency in sensory neurons J. Virol. 75 22 2001 11178 11184
27. P. Lucin, S. Jonjic, M. Messerle, B. Polic, H. Hengel, and U.H. Koszinowski Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor J. Gen. Virol. 75 Part 1 1994 101 110
28. G.D. Luker, J.L. Prior, J. Song, C.M. Pica, and D.A. Leib Bioluminescence imaging reveals systemic dissemination of herpes simplex virus type 1 in the absence of interferon receptors J. Virol. 77 20 2003 11082 11093
29. I. MacLennan, and C. Vinuesa Dendritic cells, BAFF, and APRIL innate players in adaptive antibody responses Immunity 17 3 2002 235 238
30. M. Matsumoto, N. Tanaka, H. Harada, T. Kimura, T. Yokochi, M. Kitagawa, C. Schindler, and T. Taniguchi Activation of the transcription factor ISGF3 by interferon-gamma Biol. Chem. 380 6 1999 699 703
31. L.H. Monteiro, M.A. Bussab, and J.G. Chaui Berlink Analytical results on a Wilson-Cowan neuronal network modified model J. Theor. Biol. 219 1 2002 83 91
32. D. Neumann-Haefelin, R. Sundmacher, H. Frey, and W. Merk Recombinant HuIFN-gamma prevents herpes simplex keratitis in African green monkeys demonstration of synergism with recombinant HuIFN-alpha 2 Med. Microbiol. Immunol. (Berl) 174 2 1985 81 86
33. Y. Ohmori, R.D. Schreiber, and T.A. Hamilton Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB J. Biol. Chem. 272 23 1997 14899 14907
34. S.R. Paludan Synergistic action of pro-inflammatory agents cellular and molecular aspects J. Leukoc. Biol. 67 1 2000 18 25
35. M.N. Prichard, and C. Shipman Jr. A three-dimensional model to analyze drug-drug interactions Antiviral Res. 14 4-5 1990 181 205
36. M.N. Prichard, and C. Shipman Jr. Antiviral Res. 17 1 1990 91 98
37. C.V. Ramana, M.P. Gil, R.D. Schreiber, and G.R. Stark Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling Trends Immunol. 23 2 2002 96 101
38. B. Sainz Jr., and W.P. Halford Alpha/Beta interferon and gamma interferon synergize to inhibit the replication of herpes simplex virus type 1 J. Virol. 76 22 2002 11541 11550
39. E.F. Schisterman, K.B. Moysich, L.J. England, and M. Rao Estimation of the correlation coefficient using the Bayesian approach and its applications for epidemiologic research BMC Med. Res. Methodol. 3 1 2003 5
40. A. Simmons, and D.C. Tscharke Anti-CD8 impairs clearance of herpes simplex virus from the nervous system implications for the fate of virally infected neurons J. Exp. Med. 175 5 1992 1337 1344
41. B.K. Slinker The statistics of synergism J. Mol. Cell Cardiol. 30 4 1998 723 731
42. K.O. Smith Relationship between the envelope and the infectivity of herpes simplex virus Proc. Soc. Exp. Biol. Med. 115 1964 814 816
43. P. Speck, and A. Simmons Precipitous clearance of herpes simplex virus antigens from the peripheral nervous systems of experimentally infected C57BL/10 mice J. Gen. Virol. 79 Part 3 1998 561 564
44. J. Suhnel Evaluation of synergism or antagonism for the combined action of antiviral agents Antiviral Res. 13 1 1990 23 39
45. J. Suhnel Comment on the paper a three-dimensional model to analyze drug-drug interactions Antiviral Res. 14 1992 181 206
46. K. Suzue, T. Asai, T. Takeuchi, and S. Koyasu In vivo role of IFN-gamma produced by antigen-presenting cells in early host defense against intracellular pathogens Eur. J. Immunol. 33 10 2003 2666 2675
47. A. Takaoka, Y. Mitani, H. Suemori, M. Sato, T. Yokochi, S. Noguchi, N. Tanaka, and T. Taniguchi Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains Science 288 5475 2000 2357 2360
48. R.J. Tallarida Drug Synergism and Dose-effect Analysis 2000 Chapman & Hall/CRC New York
49. R.J. Tallarida Drug synergism its detection and applications J. Pharmacol. Exp. Ther. 298 3 2001 865 872
50. R.J. Tallarida, D.J. Stone Jr., and R.B. Raffa Efficient designs for studying synergistic drug combinations Life Sci. 61 26 1997 L417 L425
51. L. Varinou, K. Ramsauer, M. Karaghiosoff, T. Kolbe, K. Pfeffer, M. Muller, and T. Decker Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity Immunity 19 6 2003 793 802
52. J. Vilcek, and J. Sen Interferons and other cytokines B.N. Fields D.M. Knipe P.M. Howley Virology 1996 Raven Publishers Philadelphia 375 400
53. S. Vollstedt, S. Arnold, C. Schwerdel, M. Franchini, G. Alber, J.P. Di Santo, M. Ackermann, and M. Suter Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1 J. Virol. 78 8 2004 3846 3850
54. J.D. Wolchok, and J. Vilcek Induction of HLA class I mRNA by cytokines in human fibroblasts comparison of TNF, IL-1 and IFN-beta Cytokine 4 6 1992 520 527
55. A. Zerial, A.G. Hovanessian, S. Stefanos, K. Huygen, G.H. Werner, and E. Falcoff Synergistic activities of type I (alpha, beta) and type II (gamma) murine interferons Antiviral Res. 2 4 1982 227 239