-
1
-
-
0025769798
-
Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics
-
Feldman PL, James MK, Brackeen MF, et al. Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics. J Med Chem 1991; 34: 2202-8
-
(1991)
J. Med. Chem.
, vol.34
, pp. 2202-2208
-
-
Feldman, P.L.1
James, M.K.2
Brackeen, M.F.3
-
2
-
-
0029867110
-
Pharmacokinetics and pharmacodynamics of remifentanil in volunteer subjects with severe liver disease
-
Dershwitz M, Hoke JF, Rosow CE, et al. Pharmacokinetics and pharmacodynamics of remifentanil in volunteer subjects with severe liver disease. Anesthesiology 1996; 84: 812-20
-
(1996)
Anesthesiology
, vol.84
, pp. 812-820
-
-
Dershwitz, M.1
Hoke, J.F.2
Rosow, C.E.3
-
3
-
-
0027375940
-
Pharmacokinetics of remifentanil (G187084B) and its major metabolite (G190291) in patients undergoing elective inpatient surgery
-
Westmoreland CL, Hoke JF, Sebel PS, Hug CC jr, Muir KT. Pharmacokinetics of remifentanil (G187084B) and its major metabolite (G190291) in patients undergoing elective inpatient surgery. Anesthesiology 1993; 79: 893-903
-
(1993)
Anesthesiology
, vol.79
, pp. 893-903
-
-
Westmoreland, C.L.1
Hoke, J.F.2
Sebel, P.S.3
Hug Jr., C.C.4
Muir, K.T.5
-
4
-
-
0030067891
-
The pharmacokinetics and extra-hepatic clearance of remifentanil, a short acting opioid agonist, in male beagle dogs during constant rate infusions
-
Chism JP, Rickert DE. The pharmacokinetics and extra-hepatic clearance of remifentanil, a short acting opioid agonist, in male beagle dogs during constant rate infusions. Drug Metab Dispos 1996; 24 34-40
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 34-40
-
-
Chism, J.P.1
Rickert, D.E.2
-
5
-
-
0024442139
-
The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part 1)
-
Chiou WL. The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part 1). Clin Pharmacokinet 1989; 17: 175-99
-
(1989)
Clin. Pharmacokinet.
, vol.17
, pp. 175-199
-
-
Chiou, W.L.1
-
6
-
-
0024461323
-
The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part II)
-
Chiou WL. The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (Part II). Clin Pharmacokinet 1989; 17: 275-90
-
(1989)
Clin. Pharmacokinet.
, vol.17
, pp. 275-290
-
-
Chiou, W.L.1
-
7
-
-
0021263542
-
Simultaneous modeling of pharmacokinetics and pharmacodynamics with a nonparametric pharmacodynamic model
-
Fuseau E, Sheiner LB. Simultaneous modeling of pharmacokinetics and pharmacodynamics with a nonparametric pharmacodynamic model. Clin Pharmacol Ther 1984; 35: 733-41
-
(1984)
Clin. Pharmacol. Ther.
, vol.35
, pp. 733-741
-
-
Fuseau, E.1
Sheiner, L.B.2
-
8
-
-
0014341045
-
Kinetics of interaction between drugs and biological systems
-
Segre G. Kinetics of interaction between drugs and biological systems. Farmaco (Sci) 1968; 23: 907-18
-
(1968)
Farmaco (Sci)
, vol.23
, pp. 907-918
-
-
Segre, G.1
-
9
-
-
0018394195
-
Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine
-
Sheiner LB, Stanski DR, Vozeh S, Miller RD, Ham J. Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 1979; 25: 358-71
-
(1979)
Clin. Pharmacol. Ther.
, vol.25
, pp. 358-371
-
-
Sheiner, L.B.1
Stanski, D.R.2
Vozeh, S.3
Miller, R.D.4
Ham, J.5
-
10
-
-
0022889587
-
Single pass mean residence time in peripheral tissues: A distribution parameter intrinsic to the tissue affinity of a drug
-
Veng-Pedersen P, Gillespie WR. Single pass mean residence time in peripheral tissues: a distribution parameter intrinsic to the tissue affinity of a drug. J Pharm Sci 1986; 75: 1119-26
-
(1986)
J. Pharm. Sci.
, vol.75
, pp. 1119-1126
-
-
Veng-Pedersen, P.1
Gillespie, W.R.2
-
11
-
-
0024518838
-
Semiparametric approach to pharmacokinetic-pharmacodynamic data
-
Verotta D, Beal SL, Sheiner LB. Semiparametric approach to pharmacokinetic-pharmacodynamic data. Am J Physiol 1989; 256: R1005-10
-
(1989)
Am. J. Physiol.
, vol.256
-
-
Verotta, D.1
Beal, S.L.2
Sheiner, L.B.3
-
12
-
-
0025782251
-
Pharmacokinetics and pharmacodynamics of atracurium obtained with arterial and venous blood samples
-
Donati F, Varin F, Ducharme J, Gill SS, Theoret Y, Bevan DR. Pharmacokinetics and pharmacodynamics of atracurium obtained with arterial and venous blood samples. Clin Pharmacol Ther 1991; 49 515-22
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 515-522
-
-
Donati, F.1
Varin, F.2
Ducharme, J.3
Gill, S.S.4
Theoret, Y.5
Bevan, D.R.6
-
13
-
-
0032964039
-
Influence of arteriovenous sampling on remifentanil pharmacokinetics and pharmacodynamics
-
Hermann DJ, Egan TD, Muir KT. Influence of arteriovenous sampling on remifentanil pharmacokinetics and pharmacodynamics. Clin Pharmocal Ther 1999; 65: 511-8
-
(1999)
Clin. Pharmocal. Ther.
, vol.65
, pp. 511-518
-
-
Hermann, D.J.1
Egan, T.D.2
Muir, K.T.3
-
14
-
-
0037419483
-
Simultaneous solid-phase extraction with liquid chromatography with ultraviolet absorbance for the determination of remifentanil and its metabolite in dog plasma
-
Kabbaj M, Varin F. Simultaneous solid-phase extraction with liquid chromatography with ultraviolet absorbance for the determination of remifentanil and its metabolite in dog plasma. J Chromatogr B Biomed Sci Appl 2003; 783: 103-9
-
(2003)
J. Chromatogr. B. Biomed. Sci. Appl.
, vol.783
, pp. 103-109
-
-
Kabbaj, M.1
Varin, F.2
-
15
-
-
0020402126
-
Pethidine binding to blood cells and plasma proteins in old and young subjects
-
Holmberg L, Odar-Cederlof I, Nilsson JL, Ehrnebo M, Boreus LO. Pethidine binding to blood cells and plasma proteins in old and young subjects. Eur J Clin Pharmacol 1982; 23: 457-61
-
(1982)
Eur. J. Clin. Pharmacol.
, vol.23
, pp. 457-461
-
-
Holmberg, L.1
Odar-Cederlof, I.2
Nilsson, J.L.3
Ehrnebo, M.4
Boreus, L.O.5
-
16
-
-
0028346218
-
Determination of remifentanil in human blood by liquid-liquid extraction and capillary GC-HRMS-SIM using a deuterated internal standard
-
Grosse CM, Davis IM, Arrendale RF, Jersey J, Amin J. Determination of remifentanil in human blood by liquid-liquid extraction and capillary GC-HRMS-SIM using a deuterated internal standard. J Pharm Biomed Anal 1994; 12: 195-203
-
(1994)
J. Pharm. Biomed. Anal.
, vol.12
, pp. 195-203
-
-
Grosse, C.M.1
Davis, I.M.2
Arrendale, R.F.3
Jersey, J.4
Amin, J.5
-
17
-
-
0019785890
-
Understanding the dose-effect relationship: Clinical application of pharmacokinetic-pharmacodynamic models
-
Holford NH, Sheiner LB. Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models. Clin Pharmacokinet 1981; 6: 429-53
-
(1981)
Clin. Pharmacokinet.
, vol.6
, pp. 429-453
-
-
Holford, N.H.1
Sheiner, L.B.2
-
18
-
-
0019825066
-
Simultaneous pharmacokinetic and pharmacodynamic modeling
-
Colburn WA. Simultaneous pharmacokinetic and pharmacodynamic modeling. J Pharmacokinet Biopharm 1981; 9: 367-88
-
(1981)
J. Pharmacokinet. Biopharm.
, vol.9
, pp. 367-388
-
-
Colburn, W.A.1
-
19
-
-
0019726137
-
Effects of morphine, fentanyl, sufentanil, and the short-acting morphine-like analgesic alfentanil on the EEG in dogs
-
Wauquier A, Van den Broeck WAE, Niemgeers CJE, Janssen PAJ. Effects of morphine, fentanyl, sufentanil, and the short-acting morphine-like analgesic alfentanil on the EEG in dogs. Drug Dev Res 1981; 1: 167-79
-
(1981)
Drug Dev. Res.
, vol.1
, pp. 167-179
-
-
Wauquier, A.1
Van den Broeck, W.A.E.2
Niemgeers, C.J.E.3
Janssen, P.A.J.4
-
20
-
-
0030911456
-
Comparative pharmacokinetics and pharmacodynamics of remifentanil, its principle metabolite (GR90291) and alfentanil in dogs
-
Hoke JF, Cunningham F, James MK, Muir KT, Hoffman WE. Comparative pharmacokinetics and pharmacodynamics of remifentanil, its principle metabolite (GR90291) and alfentanil in dogs. J Pharmacol Exp Ther 1997; 281: 226-32
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 226-232
-
-
Hoke, J.F.1
Cunningham, F.2
James, M.K.3
Muir, K.T.4
Hoffman, W.E.5
-
21
-
-
0032912419
-
The comparative pharmacodynamics of remifentanil and its metabolite, GR90291, in a rat electroencephalographic model
-
Cox EH, Langemeijer MW, Gubbens-Stibbe JM, Muir KT, Danhof M. The comparative pharmacodynamics of remifentanil and its metabolite, GR90291, in a rat electroencephalographic model. Anesthesiology 1999; 90: 535-44
-
(1999)
Anesthesiology
, vol.90
, pp. 535-544
-
-
Cox, E.H.1
Langemeijer, M.W.2
Gubbens-Stibbe, J.M.3
Muir, K.T.4
Danhof, M.5
-
22
-
-
0031422405
-
The pharmacokinetics and electroencephalogram response of remifentanil alone and in combination with esmolol in the rat
-
Haidar SH, Moreton JE, Liang Z, Hokef, Muir KT, Eddington ND. The pharmacokinetics and electroencephalogram response of remifentanil alone and in combination with esmolol in the rat. Pharm Res 1997; 14: 1817-23
-
(1997)
Pharm. Res.
, vol.14
, pp. 1817-1823
-
-
Haidar, S.H.1
Moreton, J.E.2
Liang, Z.3
Hokef, A.4
Muir, K.T.5
Eddington, N.D.6
-
23
-
-
0029983237
-
Remifentanil versus alfentanil: Comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers
-
Egan TD, Minto CF, Hermann DJ, Barr J, Muir KT, Shafer SL. Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers. Anesthesiology 1996; 84: 821-33
-
(1996)
Anesthesiology
, vol.84
, pp. 821-833
-
-
Egan, T.D.1
Minto, C.F.2
Hermann, D.J.3
Barr, J.4
Muir, K.T.5
Shafer, S.L.6
-
24
-
-
0031030419
-
Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development
-
Minto CF, Schnider TW, Egan TD, et al. Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development. Anesthesiology 1997; 86: 10-23
-
(1997)
Anesthesiology
, vol.86
, pp. 10-23
-
-
Minto, C.F.1
Schnider, T.W.2
Egan, T.D.3
-
25
-
-
0026737667
-
Electroencephalogram effect measures and relationships between pharmacokinetics and pharmacodynamics of centrally acting drugs
-
Mandema JW, Danhof M. Electroencephalogram effect measures and relationships between pharmacokinetics and pharmacodynamics of centrally acting drugs. Clin Pharmacokinet 1992; 23: 191-215
-
(1992)
Clin. Pharmacokinet.
, vol.23
, pp. 191-215
-
-
Mandema, J.W.1
Danhof, M.2
-
26
-
-
0033794545
-
Pharmacokinetic studies of neuromuscular blocking agents: Good clinical research practice (GCRP)
-
Viby-Mogensen J, Ostergaard D, Donati F, et al. Pharmacokinetic studies of neuromuscular blocking agents: good clinical research practice (GCRP). Acta Anaesthesiol Scand 2000; 44: 1169-90
-
(2000)
Acta Anaesthesiol. Scand.
, vol.44
, pp. 1169-1190
-
-
Viby-Mogensen, J.1
Ostergaard, D.2
Donati, F.3
-
27
-
-
0034991417
-
Peripheral link model as an alternative for pharmacokinetic-pharmacodynamic modeling of drugs having a very short elimination half-life
-
Laurin J, Donati F, Nekka F, Varin F. Peripheral link model as an alternative for pharmacokinetic-pharmacodynamic modeling of drugs having a very short elimination half-life. J Pharmacokinet Biopharm 2001; 28: 7-25
-
(2001)
J. Pharmacokinet. Biopharm.
, vol.28
, pp. 7-25
-
-
Laurin, J.1
Donati, F.2
Nekka, F.3
Varin, F.4
-
28
-
-
0034753867
-
Anatomical-physiological approaches in pharmacokinetics and pharmacodynamics
-
Mather LE. Anatomical-physiological approaches in pharmacokinetics and pharmacodynamics. Clin Pharmacokinet 2001; 40: 707-22
-
(2001)
Clin. Pharmacokinet.
, vol.40
, pp. 707-722
-
-
Mather, L.E.1
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