Mechanisms of the natural reactivity of lymphocytes from noninfected individuals to membrane-associated Leishmania infantum antigens

Journal of Immunology

Volumn 174, Issue 6, 2005, Pages 3598-3607

  Sassi, Atfa ^a   Larguèche Darwaz, Beya ^a   Collette, Alexis ^b   Six, Adrien ^b   Laouini, Dhafer ^a   Cazenave, Pierre André ^b   Dellagi, Koussay ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PARASITE ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEISHMANIA INFANTUM; LEISHMANIASIS; LYMPHOCYTE PROLIFERATION; MONONUCLEAR CELL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 14844348774     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.6.3598     Document Type: Article

References (48)

1. Badaro, R., T. C. Jones, E. M. Carvalho, D. Sampaio, S. G. Reed, A. Barral, R. Teixeira, and W. D. Johnson, Jr. 1986. New perspectives on a subclinical form of visceral leishmaniasis. J. Infect. Dis. 154:1003.
2. Ben Salah, A. B., R. Ben Ismail, F. Amri, S. Chlif, F. Ben Rzig, H. Kharrat, H. Hadhri, M. Hassouna, and K. Dellagi. 2000. Investigation of the spread of human visceral leishmaniasis in central Tunisia. Trans. R. Soc. Trop. Med. Hyg. 94:382.
3. + T cells in leishmaniasis. Immunol. Today 10:40.
4. Kharazmi, A., K. Kemp, A. Ismail, S. Gasim, A. Gaafar, J. A. Kurtzhals, A. M. El Hassan, T. G. Theander, and M. Kemp. 1999. T-cell response in human leishmaniasis. Immunol. Lett. 65:105.
5. Carvalho, E. M., R. Badaro, S. G. Reed, T. C. Jones, and W. D. Johnson, Jr. 1985. Absence of γ interferon and interleukin 2 production during active visceral leishmaniasis. J. Clin. Invest. 76:2066.
6. Ghalib, H. W., J. A. Whittle, M. Kubin, F. A. Hashim, A. M. el-Hassan, K. H. Grabstein, G. Trinchieri, and S. G. Reed. 1995. IL-12 enhances Th1-type responses in human Leishmania donovani infections. J. Immunol. 154:4623.
7. Holaday, B. J., M. M. Pompeu, S. Jeronimo, M. J. Texeira, A. Sousa Ade, A. W. Vasconcelos, R. D. Pearson, J. S. Abrams, and R. M. Locksley. 1993. Potential role for interleukin-10 in the immunosuppression associated with kala azar. J. Clin. Invest. 92:2626.
8. Trinchieri, G. 1995. Interleukin-12: a proinfiammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
9. Akuffo, H., K. Maasho, and R. Howe. 1993. Natural and acquired resistance to Leishmania: cellular activation by Leishmania aethiopica of mononuclear cells from unexposed individuals is through the stimulation of natural killer (NK) cells. Clin. Exp. Immunol. 94:516.
10. Kemp, M., M. B. Hansen, and T. G. Theander. 1992. Recognition of Leishmania antigens by T lymphocytes from nonexposed individuals. Infect. Immun. 60:2246.
11. Kurtzhals, J. A., M. Kemp, L. K. Poulsen, M. B. Hansen, A. Kharazmi, and T. G. Theander. 1995. Interleukin-4 and interferon-γ production by Leishmania stimulated peripheral blood mononuclear cells from nonexposed individuals. Scand. J. Immunol. 41:343.
12. + T cells generated in response to LACK in naive subjects never exposed to Leishmania. Eur. J. Immunol. 32:510.
13. Jensen, A. T., K. Kemp, T. G. Theander, and E. Handman. 2001. Cloning, expression and antigenicity of the L. donovani reductase. APMIS 109:461.
14. Sassi, A., H. Louzir, A. Ben Salah, M. Mokni, A. Ben Osman, and K. Dellagi. 1999. Leishmanin skin test lymphoproliferative responses and cytokine production after symptomatic or asymptomatic Leishmania major infection in Tunisia. Clin. Exp. Immunol. 116:127.
15. Dwyer, D. M. 1980. Isolation and partial characterization of surface membranes from Leishmania donovani promastigotes. J. Protozool. 27:176.
16. Scott, P., E. Pearce, P. Natovitz, and A. Sher. 1987. Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes. J. Immunol. 139:221.
17. Mendonca, S. C., D. G. Russell, and S. G. Coutinho. 1991. Analysis of the human T cell responsiveness to purified antigens of Leishmania: lipophosphoglycan (LPG) and glycoprotein 63 (gp 63). Clin. Exp. Immunol. 83:472.
18. Roska, A. K., and P. E. Lipsky. 1985. Dissection of the functions of antigen-presenting cells in the induction of T cell activation. J. Immunol. 135:2953.
19. Ohmen, J. D., P. F. Barnes, C. L. Grisso, B. R. Bloom, and R. L. Modlin. 1994. Evidence for a superantigen in human tuberculosis. Immunity 1:35.
20. Pannetier, C., J. Even, and P. Kourilsky. 1995. T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol. Today 16:176.
21. Pannetier, C., S. Delassus, S. Darche, C. Saucier, and P. Kourilsky. 1993. Quantitative titration of nucleic acids by enzymatic amplification reactions run to saturation. Nucleic Acids Res. 21:577.
22. Collette, A., and A. Six. 2002. ISEApeaks: an Excel platform for GeneScan and Immunoscope data retrieval, management and analysis. Bioinformaiics 18:329.
23. + repertoire during antiviral therapy. Nat. Med. 4:215.
24. Kappler, J., B. Kotzin, L. Herron, E. W. Gelfand, R. D. Bigler, A. Boylston, S. Carrel, D. N. Posnett, Y. Choi, and P. Marrack. 1989. Vβ-spedfic Stimulation of human T cells by staphylococcal toxins. Science 244:811.
25. Choi, Y. W., B. Kotzin, L. Herron, J. Callahan, P. Marrack, and J. Kappler. 1989. Interaction of Staphylococcus aureus toxin " superantigens" with human T cells. Proc. Natl. Acad. Sci. USA 86:8941.
26. Caramalho, I., T. Lopes-Carvalho, D. Ostler, S. Zelenay, M. Haury, and J. Demengeot. 2003. Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J. Exp. Med. 197:403.
27. + T cell survival. J. Immunol. 172:6065.
28. Hornung, V., S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdorfer, T. Giese, S. Endres, and G. Hartmann. 2002. Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol. 168:4531.
29. Piuvezam, M. R., D. M. Russo, J. M. Burns, Jr., Y. A. Skeiky, K. H. Grabstein, and S. G. Reed. 1993. Characterization of responses of normal human T cells to Trypanosoma cruzi antigens. J. Immunol. 150:916.
30. Subauste, C. S., F. Fuh, R. de Waal Malefyt, and J. S. Remington. 1998. αβ T cell response to Toxoplasma gondii in previously unexposed individuals. J. Immunol. 160:3403.
31. + T cell responses common to Plasmodium falciparum and recall antigens. Int. Immunol. 9:1857.
32. + lymphocytes. J. Exp. Med. 180:985.
33. Pied, S., D. Voegtle, M. Marussig, L. Renia, F. Miltgen, D. Mazier, and P. A. Cazenave. 1997. Evidence for superantigenic activity during murine malaria infection. Int. Immunol. 9:17.
34. Nylen, S., K. Maasho, K. Soderstrom, T. Ilg, and H. Akuffo. 2003. Live Leishmania promastigotes can directly activate primary human natural killer cells to produce interferon-γ. Clin. Exp. Immunol. 131:457.
35. McMahon-Pratt, D., and J. Alexander. 2004. Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease? Immunol. Rev. 201:206.
36. + human T cells in vitro. J. Immunol. 160:351.
37. Wilson, C. B. 1991. The ontogeny of T lymphocyte maturation and function. J. Pediatr. 118:54.
38. Ulrichs, T., and S. A. Porcelli. 2000. CD1 proteins: targets of T cell recognition in innate and adaptive immunity. Rev. Immunogenet. 2:416.
39. Sugita, M., P. J. Peters, and M. B. Brenner. 2000. Pathways for lipid antigen presentation by CD1 molecules: nowhere for intracellular pathogens to hide. Traffic 1:295.
40. Beutler, B., K. Hoebe, X. Du, and R. J. Ulevitch. 2003. How we detect microbes and respond to them: the Toll-like receptors and their transducers. J. Leukocyte Biol. 74:479.
41. van Kooyk, Y., and T. B. Geijtenbeek. 2003. DC-SIGN: escape mechanism for pathogens. Nat. Rev. Immunol. 3:697.
42. Colmenares, M., A. L. Corbi, S. J. Turco, and L. Rivas. 2004. The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania. J. Immunol. 172:1186.
43. Becker, I., N. Salaiza, M. Aguirre, J. Delgado, N. Carrillo-Carrasco, L. G. Kobeh, A. Ruiz, R. Cervantes, A. P. Torres, N. Cabrera, et al. 2003. Leishmania lipophosphoglycan (LPG) activates NK cells through Toll-like receptor-2. Mol. Biochem. Parasitol. 130:65.
44. Bacellar, O., C. Brodskyn, J. Guerreiro, M. Barral-Netto, C. H. Costa, R. L. Coffman, W. D. Johnson, and E. M. Carvalho. 1996. Interleukin-12 restores interferon-γ production and cytotosic responses in visceral leishmaniasis. J. Infect. Dis. 173:1515.
45. De Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdor, and J. E. de Vries. 1991. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of 1L-10 produced by monocytes. J. Exp. Med. 174:1209.
46. Murphy, M. L., U. Wille, E. N. Villegas, C. A. Hunter, and J. P. Farrell. 2001. IL-10 mediates susceptibility to Leishmania donovani infection. Eur. J. Immunol. 31:2848.
47. Ghalib, H. W., M. R. Piuvezam, Y. A. Skeiky, M. Siddig, F. A. Hashim, A. M. el-Hassan, D. M. Russo, and S. G. Reed. 1993. Interleukin 10 production correlates with pathology in human Leishmania donovani infections. J. Clin. Invest. 92:324.
48. + regulatory T cells control Leishmania major persistence and immunity. Nature 420:502.